THE IMPORTANT HORMONES OF THE ADRENAL GLANDS(ALDOSTERONE) Flashcards

1
Q

What are the hormones of the adrenal glands

A

ALDOSTERONE
CORTISOL
ADRENAL SEX HORMONES

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2
Q

What causes the kidneys to conserve Na+ and H20, and to excrete K+?

A

ALDOSTERONE

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3
Q

What do Aldosterone conserve?

A

Na+ and H20, and to excrete K+.

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4
Q

The release of Aldosterone is stimulated by?

A

a decreased in serum SODIUM levels

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5
Q

What do Aldosterone promotes?

A

tubular reabsorption of sodium in the kidneys
Promotes excretion of potassium and hydrogen

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6
Q

The production of Aldosterone is controlled by?

A

RAAS

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7
Q

For the reference ranges, complete the following.
A. Adult supine: ___________
B. Adult upright: ____________

A

3-16mg/dL
7-30mg/dL

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8
Q

Aldosterone is higher in the morning or evening?

A

Morning

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9
Q

Under RAAS, dehydration will cause?

A

decreased blood volume that will later on cause hypotension

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10
Q

What organ produces RENIN?

A

Kidneys

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11
Q

This enzyme converts angiotensin I to II?

A

Angiotensin-converting enzyme (ACE)

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12
Q

RAAS, starts with a decrease in BP, therefore what will detect this?

A

Juxtamedullary apparatus

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13
Q

What are the functions of Angiotensin II?

A
  1. Potent vasoconstrictor
  2. Stimulate adrenal cortex to release aldosterone
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14
Q
  1. Potent vasoconstrictor = _________________
A

Increases blood pressure

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15
Q
  1. Stimulate adrenal cortex to release aldosterone = ______________?
A

increases Na+ and H2O resorption

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16
Q

What are the clinical significance of aldosterone

A

HYPERALDOSTERONISM
HYPOALDOSTERONISM

17
Q

What are the types of Hyperaldosteronism?

A

Primary hyperaldosteronism
Secondary hyperaldosteronism

18
Q

What causes primary hyperaldosteronism?

A

aldosterone-secreting adrenal carcinoma
hyperplasia

19
Q

It is the abnormal increase of the number of cells causing enlargement of the organ

A

hyperplasia

20
Q

increased in the size of the cell

A

Hypertrophy

21
Q

This type of hyperaldosteronism refers to the adrenal glands are functioning properly however the problem in here is how the other organ systems respond to it.

A

Secondary hyperaldosteronism

22
Q

What causes Renin-angiotensin system disorder?

A

excess production of renin
malignant hypertension
renin-secreting renal tumor

23
Q

What causes hypoaldosteronism?

A
  1. Atrophy of adrenal gland
  2. Symptoms of Addison disease
  3. Congenital deficiency of 21 – hydroxylase enzyme
24
Q

This refers to the Reduction is cell size or number of cells that causes decrease in the total mass/ size of the organ

A

Atrophy of adrenal gland

25
Q

What is the symptoms of Addison disease?

A

Atrophy of adrenal glands with depressed production of aldosterone and glucocorticoids

26
Q

If a patient has an Addison’s disease, what could the patient experience?

A

Hypoadrenalism

27
Q

Decrease secretion of both aldosterone and cortisol but with a high ACTH and MSH

A

hypoadrenalism

28
Q

What stimulates the secretion of Cortisol?

A

Adrenocorticotropic Hormone (ACTH)

29
Q

This enzyme converts steroid precursors to aldosterone and cortisol.

A

Congenital deficiency of 21 – hydroxylase enzyme

30
Q

What do Congenital deficiency of 21 – hydroxylase enzyme converts?

A

steroids precursors to aldosterone and cortisol.

31
Q

In aldosterone assay, what specimens does it use?

A

Plasma (fasting)
Urine

32
Q

Levels in pregnant patients are ____________ higher

A

three to four times

33
Q

Collect 24hr specimen in _______________ to maintain ___________?

A

10g boric acid
pH <7.5