THE IMPORTANT HORMONES OF THE ADRENAL GLANDS(ALDOSTERONE) Flashcards
What are the hormones of the adrenal glands
ALDOSTERONE
CORTISOL
ADRENAL SEX HORMONES
What causes the kidneys to conserve Na+ and H20, and to excrete K+?
ALDOSTERONE
What do Aldosterone conserve?
Na+ and H20, and to excrete K+.
The release of Aldosterone is stimulated by?
a decreased in serum SODIUM levels
What do Aldosterone promotes?
tubular reabsorption of sodium in the kidneys
Promotes excretion of potassium and hydrogen
The production of Aldosterone is controlled by?
RAAS
For the reference ranges, complete the following.
A. Adult supine: ___________
B. Adult upright: ____________
3-16mg/dL
7-30mg/dL
Aldosterone is higher in the morning or evening?
Morning
Under RAAS, dehydration will cause?
decreased blood volume that will later on cause hypotension
What organ produces RENIN?
Kidneys
This enzyme converts angiotensin I to II?
Angiotensin-converting enzyme (ACE)
RAAS, starts with a decrease in BP, therefore what will detect this?
Juxtamedullary apparatus
What are the functions of Angiotensin II?
- Potent vasoconstrictor
- Stimulate adrenal cortex to release aldosterone
- Potent vasoconstrictor = _________________
Increases blood pressure
- Stimulate adrenal cortex to release aldosterone = ______________?
increases Na+ and H2O resorption
What are the clinical significance of aldosterone
HYPERALDOSTERONISM
HYPOALDOSTERONISM
What are the types of Hyperaldosteronism?
Primary hyperaldosteronism
Secondary hyperaldosteronism
What causes primary hyperaldosteronism?
aldosterone-secreting adrenal carcinoma
hyperplasia
It is the abnormal increase of the number of cells causing enlargement of the organ
hyperplasia
increased in the size of the cell
Hypertrophy
This type of hyperaldosteronism refers to the adrenal glands are functioning properly however the problem in here is how the other organ systems respond to it.
Secondary hyperaldosteronism
What causes Renin-angiotensin system disorder?
excess production of renin
malignant hypertension
renin-secreting renal tumor
What causes hypoaldosteronism?
- Atrophy of adrenal gland
- Symptoms of Addison disease
- Congenital deficiency of 21 – hydroxylase enzyme
This refers to the Reduction is cell size or number of cells that causes decrease in the total mass/ size of the organ
Atrophy of adrenal gland
What is the symptoms of Addison disease?
Atrophy of adrenal glands with depressed production of aldosterone and glucocorticoids
If a patient has an Addison’s disease, what could the patient experience?
Hypoadrenalism
Decrease secretion of both aldosterone and cortisol but with a high ACTH and MSH
hypoadrenalism
What stimulates the secretion of Cortisol?
Adrenocorticotropic Hormone (ACTH)
This enzyme converts steroid precursors to aldosterone and cortisol.
Congenital deficiency of 21 – hydroxylase enzyme
What do Congenital deficiency of 21 – hydroxylase enzyme converts?
steroids precursors to aldosterone and cortisol.
In aldosterone assay, what specimens does it use?
Plasma (fasting)
Urine
Levels in pregnant patients are ____________ higher
three to four times
Collect 24hr specimen in _______________ to maintain ___________?
10g boric acid
pH <7.5