The Alcohols & Etc Flashcards
Naltrexone
Drug used in chronic alcoholism
Drugs used in chronic alcoholism
Naltrexone
Acamprosate
Disulfiram
Acamprosate
Drug used in chronic alcoholism
Disulfiram
Drug used in chronic alcoholism
Naltrexone
Mechanism of action
Nonselective competitive anatgonist of opioid receptors
Nonselective competitive anatgonist of opioid receptors
Naltrexone
Mechanism of action
Acamprosate
Mechanism of action
Poorly understood NMDA receptor antagonist and GABA(A) agonist effects
Poorly understood NMDA receptor antagonist and GABA(A) agonist effects
Acamprosate
Mechanism of action
Naltrexone
Acamprosate
Clinical applications
Reduced risk of relapse in individuals with alcoholism
Reduced risk of relapse in individuals with alcoholism
Naltrexone
Acamprosate
Clinical applications
Naltrexone
Toxicity
GI effects and liver toxicity
Will precipitate a withdrawal reaction in individuals physically dependent on opioids and will prevent the analgesic effect of opioids
GI effects and liver toxicity
Will precipitate a withdrawal reaction in individuals physically dependent on opioids and will prevent the analgesic effect of opioids
Naltrexone
Toxicity
Acamprosate
Naltrexone
Clinical application
Reduced risk of relapse in individuals with alcoholism
Disulfiram
Mechanism of action
Inhibits aldehyde dehydrogenase, resulting in aldehyde accumulation during ethanol ingestion
Inhibits aldehyde dehydrogenase, resulting in aldehyde accumulation during ethanol ingestion
Disulfiram
Mechanism of action
Disulfiram
Clinical application
Deterrent to drinking in individuals with alcohol dependence
Deterrent to drinking in individuals with alcohol dependence
Disulfiram
Clinical application
Disulfiram
Toxicity
Little effect alone but severe and potentialy dangerous flushing, headache, nausea, vometing, and hypotension when combined with ethanol
Little effect alone but severe and potentialy dangerous flushing, headache, nausea, vometing, and hypotension when combined with ethanol
Disulfiram
Toxicity
