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Pharma > The Alcohols & Etc > Flashcards

The Alcohols & Etc Flashcards

0
Q

Naltrexone

A

Drug used in chronic alcoholism

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1
Q

Drugs used in chronic alcoholism

A

Naltrexone
Acamprosate
Disulfiram

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2
Q

Acamprosate

A

Drug used in chronic alcoholism

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3
Q

Disulfiram

A

Drug used in chronic alcoholism

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4
Q

Naltrexone

Mechanism of action

A

Nonselective competitive anatgonist of opioid receptors

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5
Q

Nonselective competitive anatgonist of opioid receptors

A

Naltrexone

Mechanism of action

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6
Q

Acamprosate

Mechanism of action

A

Poorly understood NMDA receptor antagonist and GABA(A) agonist effects

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7
Q

Poorly understood NMDA receptor antagonist and GABA(A) agonist effects

A

Acamprosate

Mechanism of action

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8
Q

Naltrexone
Acamprosate

Clinical applications

A

Reduced risk of relapse in individuals with alcoholism

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9
Q

Reduced risk of relapse in individuals with alcoholism

A

Naltrexone
Acamprosate

Clinical applications

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10
Q

Naltrexone

Toxicity

A

GI effects and liver toxicity
Will precipitate a withdrawal reaction in individuals physically dependent on opioids and will prevent the analgesic effect of opioids

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11
Q

GI effects and liver toxicity
Will precipitate a withdrawal reaction in individuals physically dependent on opioids and will prevent the analgesic effect of opioids

A

Naltrexone

Toxicity

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12
Q

Acamprosate
Naltrexone

Clinical application

A

Reduced risk of relapse in individuals with alcoholism

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13
Q

Disulfiram

Mechanism of action

A

Inhibits aldehyde dehydrogenase, resulting in aldehyde accumulation during ethanol ingestion

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14
Q

Inhibits aldehyde dehydrogenase, resulting in aldehyde accumulation during ethanol ingestion

A

Disulfiram

Mechanism of action

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15
Q

Disulfiram

Clinical application

A

Deterrent to drinking in individuals with alcohol dependence

16
Q

Deterrent to drinking in individuals with alcohol dependence

A

Disulfiram

Clinical application

17
Q

Disulfiram

Toxicity

A

Little effect alone but severe and potentialy dangerous flushing, headache, nausea, vometing, and hypotension when combined with ethanol

18
Q

Little effect alone but severe and potentialy dangerous flushing, headache, nausea, vometing, and hypotension when combined with ethanol

A

Disulfiram

Toxicity

Pharma (29 decks)

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