Drugs Used In Asthma Flashcards
Albuterol
Selective Beta2 agonist
Beta agonists
Albuterol Salmeterol Metaproterenol Terbutaline Formoterol Epinephrine Isoproterenol
Salmeterol
Selective Beta2 agonist
Metaproterenol
Selective Beta2 agonist
Terbutaline
Selective Beta2 agonist
Formoterol
Selective Beta2 agonist
Albuterol
Mechanism of action
Selective Beta2 agonist
Salmeterol
Mechanism of action
Selective Beta2 agonist
Albuterol
Effect
Prompt, efficacious bronchodilation
Prompt, efficacious bronchodilation
Albuterol
Effect
Salmeterol
Effects
Slow onset, primarily preventive action; potentiates corticosteroid effects
Slow onset, primarily preventive action; potentiates corticosteroid effects
Salmeterol
Effects
Albuterol
Clinical applications
Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm
Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm
Albuterol
Clinical applications
Salmeterol
Clinical applications
Asthma prophylaxis
Asthma prophylaxis
Salmeterol
Clinical applications
Albuterol
Toxicity
Tremor
Tachycardia
Overdose: arrhythmias
Tremor
Tachycardia
Overdose: arrhythmias
Albuterol
Salmeterol
Toxicity
Salmeterol
Toxicity
Tremor
Tachycardia
Overdose: arrhythmias
Epinephrine
Nonselective Alpha and Beta agonist
Nonselective Alpha and Beta agonist
Epinephrine
Epinephrine
Mechanism of action
Nonselective Alpha and Beta agonist
Epinephrine
Effects
Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems
Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems
Epinephrine
Effects
Epinephrine
Clinical applications
Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)
Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)
Epinephrine
Clinical applications
Isoproterenol
Beta1 and Beta2 agonist
Beta1 and Beta2 agonist
Isoproterenol
Isoproterenol
Mechanism of action
Beta1 and Beta2 agonist
Isoproterenol
Effects
Bronchodilation plus powerful cardiovascular effects
Bronchodilation plus powerful cardiovascular effects
Isoproterenol
Effects
Isoproterenol
Clinical applications
Asthma (but Beta2-selective agents preferred)
Asthma (but Beta2-selective agents preferred)
Isoproterenol
Clinical applications
Corticosteroids, inhaled
Fluticasone
Beclomethasone
Budesonide
Flunisolide
Fluticasone
Corticosteroid, inhaled
Beclomethasone
Corticosteroid, inhaled
Budesonide
Corticosteroid, inhaled
Flunisolide
Corticosteroid, inhaled
Corticosteroids, inhaled
Mechanism of action
Alters gene expression
Corticosteroids, inhaled
Mechanism of action
Alters gene expression
Alters gene expression
Corticosteroids, inhaled
Corticosteriods, systemic
Mechanism of action
Corticosteroids, systemic
Mechanism of action
Alters gene expression
Fluticasone
Mechanism of action
Alters gene expression
Budesonide
Mechanism of action
Alters gene expression
Beclomethasone
Mechanism of action
Alters gene expression
Corticosteriods, inhaled
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Corticosteriods, systemic
Effects
Corticosteriods, systemic
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Prednisone
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Methylprednisolone
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Betclomethasone
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Budesonide
Effects
Reduces mediators of inflammation
Powerful prophylaxis of exacerbations
Corticosteroids, inhaled
Clinical applications
Asthma
Adjunct in COPD
Hay fever (nasal)
Asthma
Adjunct in COPD
Hay fever (nasal)
Corticosteroids, inhaled
Clinical applications
Corticosteroids, systemic
Clinical applications
Asthma
Adjunct in COPD
Asthma
Adjunct in COPD
Corticosteroids, systemic
Clinical applications
Corticosteroids
Fluticasone Beclomethasone Budesonide Flunisolide Prednisone Methylprednisolone
Fluticasone Beclomethasone Budesonide Flunisolide Prednisone Methylprednisolone
Corticosteroids
Stabilizers of mast and other cells
Cromolyn
Nedocromil
Cromolyn
Stabilizers of mast and other cells
Nedocromil
Stabilizers of mast and other cells
Nedocromil
Cromolyn
Mechanism of action
Alter function of delayed chloride channels
Inhibits inflammatory cell activation
Alter function of delayed chloride channels
Inhibits inflammatory cell activation
Nedocromil
Cromolyn
Mechanism of action
Nedocromil
Cromolyn
Effects
Prevents acute bronchospasm
Prevents acute bronchospasm
Nedocromil
Cromolyn
Effects
Nedocromil
Cromolyn
Clinical applications
Asthma
other routes used for ocular, nasal ang GI allergy
Asthma
other routes used for ocular, nasal ang GI allergy
Nedocromil
Cromolyn
Clinical applications
Methylxanthine
Theophylline
Theophylline
Methylxanthine
Theophylline
Mechanism of action
Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist
Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist
Theophylline
Mechanism of action
Theophylline
Effects
Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)
Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)
Theophylline
Effects
Theophylline
Clinical applications
Asthma
COPD
Asthma
COPD
Theophylline
Clinical applications
Leukotriene antagonists
Montelukast
Zafirlukast
Montelukast
Leukotriene antagonist
Zafirlukast
Leukotriene antagonist
Montelukast
Mechanism of action
Block leukotriene D4 receptors
Block leukotriene D4 receptors
Montelukast
Zafirlukast
Mechanism of action
Montelukast
Effects
Block airway response to exercise and antigen challange
Block airway response to exercise and antigen challange
Montelukast
Zafirlukast
Effects
Montelukast
Clinical applications
Prophylaxis of asthma especially in children and in aspirine-induced asthma
Prophylaxis of asthma especially in children and in aspirine-induced asthma
Montelukast
Zafirlukast
Clinical applications
IgE antibody
Omalizumab
Omalizumab
IgE antibody
Omalizumab
Mechanism of action
Humanized IgE antibody reduces circulating IgE
Humanized IgE antibody reduces circulating IgE
Omalizumab
Mechanism of action
Omalizumab
Effects
Reduces frequency of asthma exacerbaration
Omalizumab
Clinical application
Severe asthma inadequatly controlled by other agents