Drugs Used In Asthma Flashcards

0
Q

Albuterol

A

Selective Beta2 agonist

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1
Q

Beta agonists

A
Albuterol
Salmeterol
Metaproterenol
Terbutaline
Formoterol
Epinephrine
Isoproterenol
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2
Q

Salmeterol

A

Selective Beta2 agonist

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3
Q

Metaproterenol

A

Selective Beta2 agonist

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4
Q

Terbutaline

A

Selective Beta2 agonist

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5
Q

Formoterol

A

Selective Beta2 agonist

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6
Q

Albuterol

Mechanism of action

A

Selective Beta2 agonist

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7
Q

Salmeterol

Mechanism of action

A

Selective Beta2 agonist

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8
Q

Albuterol

Effect

A

Prompt, efficacious bronchodilation

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9
Q

Prompt, efficacious bronchodilation

A

Albuterol

Effect

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10
Q

Salmeterol

Effects

A

Slow onset, primarily preventive action; potentiates corticosteroid effects

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11
Q

Slow onset, primarily preventive action; potentiates corticosteroid effects

A

Salmeterol

Effects

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12
Q

Albuterol

Clinical applications

A

Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm

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13
Q

Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm

A

Albuterol

Clinical applications

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14
Q

Salmeterol

Clinical applications

A

Asthma prophylaxis

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15
Q

Asthma prophylaxis

A

Salmeterol

Clinical applications

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16
Q

Albuterol

Toxicity

A

Tremor
Tachycardia
Overdose: arrhythmias

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17
Q

Tremor
Tachycardia
Overdose: arrhythmias

A

Albuterol
Salmeterol

Toxicity

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18
Q

Salmeterol

Toxicity

A

Tremor
Tachycardia
Overdose: arrhythmias

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19
Q

Epinephrine

A

Nonselective Alpha and Beta agonist

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20
Q

Nonselective Alpha and Beta agonist

A

Epinephrine

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21
Q

Epinephrine

Mechanism of action

A

Nonselective Alpha and Beta agonist

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22
Q

Epinephrine

Effects

A

Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems

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23
Q

Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems

A

Epinephrine

Effects

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24
Q

Epinephrine

Clinical applications

A

Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)

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25
Q

Anaphylaxis
Asthma
(Others)
Rarely used for asthma (Beta2-selective agents preferred)

A

Epinephrine

Clinical applications

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26
Q

Isoproterenol

A

Beta1 and Beta2 agonist

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27
Q

Beta1 and Beta2 agonist

A

Isoproterenol

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28
Q

Isoproterenol

Mechanism of action

A

Beta1 and Beta2 agonist

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29
Q

Isoproterenol

Effects

A

Bronchodilation plus powerful cardiovascular effects

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30
Q

Bronchodilation plus powerful cardiovascular effects

A

Isoproterenol

Effects

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31
Q

Isoproterenol

Clinical applications

A

Asthma (but Beta2-selective agents preferred)

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32
Q

Asthma (but Beta2-selective agents preferred)

A

Isoproterenol

Clinical applications

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33
Q

Corticosteroids, inhaled

A

Fluticasone
Beclomethasone
Budesonide
Flunisolide

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34
Q

Fluticasone

A

Corticosteroid, inhaled

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35
Q

Beclomethasone

A

Corticosteroid, inhaled

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36
Q

Budesonide

A

Corticosteroid, inhaled

37
Q

Flunisolide

A

Corticosteroid, inhaled

38
Q

Corticosteroids, inhaled

Mechanism of action

A

Alters gene expression

39
Q

Corticosteroids, inhaled

Mechanism of action

A

Alters gene expression

40
Q

Alters gene expression

A

Corticosteroids, inhaled
Corticosteriods, systemic

Mechanism of action

41
Q

Corticosteroids, systemic

Mechanism of action

A

Alters gene expression

42
Q

Fluticasone

Mechanism of action

A

Alters gene expression

43
Q

Budesonide

Mechanism of action

A

Alters gene expression

44
Q

Beclomethasone

Mechanism of action

A

Alters gene expression

45
Q

Corticosteriods, inhaled

Effects

A

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

46
Q

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

A

Corticosteriods, systemic

Effects

47
Q

Corticosteriods, systemic

Effects

A

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

48
Q

Prednisone

Effects

A

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

49
Q

Methylprednisolone

Effects

A

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

50
Q

Betclomethasone

Effects

A

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

51
Q

Budesonide

Effects

A

Reduces mediators of inflammation

Powerful prophylaxis of exacerbations

52
Q

Corticosteroids, inhaled

Clinical applications

A

Asthma
Adjunct in COPD
Hay fever (nasal)

53
Q

Asthma
Adjunct in COPD
Hay fever (nasal)

A

Corticosteroids, inhaled

Clinical applications

54
Q

Corticosteroids, systemic

Clinical applications

A

Asthma

Adjunct in COPD

55
Q

Asthma

Adjunct in COPD

A

Corticosteroids, systemic

Clinical applications

56
Q

Corticosteroids

A
Fluticasone
Beclomethasone
Budesonide
Flunisolide
Prednisone
Methylprednisolone
57
Q
Fluticasone
Beclomethasone
Budesonide
Flunisolide
Prednisone
Methylprednisolone
A

Corticosteroids

58
Q

Stabilizers of mast and other cells

A

Cromolyn

Nedocromil

59
Q

Cromolyn

A

Stabilizers of mast and other cells

60
Q

Nedocromil

A

Stabilizers of mast and other cells

61
Q

Nedocromil
Cromolyn

Mechanism of action

A

Alter function of delayed chloride channels

Inhibits inflammatory cell activation

62
Q

Alter function of delayed chloride channels

Inhibits inflammatory cell activation

A

Nedocromil
Cromolyn

Mechanism of action

63
Q

Nedocromil
Cromolyn

Effects

A

Prevents acute bronchospasm

64
Q

Prevents acute bronchospasm

A

Nedocromil
Cromolyn

Effects

65
Q

Nedocromil
Cromolyn

Clinical applications

A

Asthma

other routes used for ocular, nasal ang GI allergy

66
Q

Asthma

other routes used for ocular, nasal ang GI allergy

A

Nedocromil
Cromolyn

Clinical applications

67
Q

Methylxanthine

A

Theophylline

68
Q

Theophylline

A

Methylxanthine

69
Q

Theophylline

Mechanism of action

A

Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist

70
Q

Uncertain
Phosphodiesterase inhibition
Adenosine receptor antagonist

A

Theophylline

Mechanism of action

71
Q

Theophylline

Effects

A

Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)

72
Q

Bronchodilation
Cardiac stimulation
Increased skeletal muscle strength (diaphragm)

A

Theophylline

Effects

73
Q

Theophylline

Clinical applications

A

Asthma

COPD

74
Q

Asthma

COPD

A

Theophylline

Clinical applications

75
Q

Leukotriene antagonists

A

Montelukast

Zafirlukast

76
Q

Montelukast

A

Leukotriene antagonist

77
Q

Zafirlukast

A

Leukotriene antagonist

78
Q

Montelukast

Mechanism of action

A

Block leukotriene D4 receptors

79
Q

Block leukotriene D4 receptors

A

Montelukast
Zafirlukast

Mechanism of action

80
Q

Montelukast

Effects

A

Block airway response to exercise and antigen challange

81
Q

Block airway response to exercise and antigen challange

A

Montelukast
Zafirlukast

Effects

82
Q

Montelukast

Clinical applications

A

Prophylaxis of asthma especially in children and in aspirine-induced asthma

83
Q

Prophylaxis of asthma especially in children and in aspirine-induced asthma

A

Montelukast
Zafirlukast

Clinical applications

84
Q

IgE antibody

A

Omalizumab

85
Q

Omalizumab

A

IgE antibody

86
Q

Omalizumab

Mechanism of action

A

Humanized IgE antibody reduces circulating IgE

87
Q

Humanized IgE antibody reduces circulating IgE

A

Omalizumab

Mechanism of action

88
Q

Omalizumab

Effects

A

Reduces frequency of asthma exacerbaration

89
Q

Omalizumab

Clinical application

A

Severe asthma inadequatly controlled by other agents