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Drugs Used In Asthma Flashcards

0
Q

Albuterol

A

Selective Beta2 agonist

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1
Q

Beta agonists

A 
Albuterol
Salmeterol
Metaproterenol
Terbutaline
Formoterol
Epinephrine
Isoproterenol
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2
Q

Salmeterol

A

Selective Beta2 agonist

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3
Q

Metaproterenol

A

Selective Beta2 agonist

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4
Q

Terbutaline

A

Selective Beta2 agonist

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5
Q

Formoterol

A

Selective Beta2 agonist

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6
Q

Albuterol

Mechanism of action

A

Selective Beta2 agonist

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7
Q

Salmeterol

Mechanism of action

A

Selective Beta2 agonist

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8
Q

Albuterol

Effect

A

Prompt, efficacious bronchodilation

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9
Q

Prompt, efficacious bronchodilation

A

Albuterol

Effect

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10
Q

Salmeterol

Effects

A

Slow onset, primarily preventive action; potentiates corticosteroid effects

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11
Q

Slow onset, primarily preventive action; potentiates corticosteroid effects

A

Salmeterol

Effects

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12
Q

Albuterol

Clinical applications

A

Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm

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13
Q

Asthma
Chronic obstructive pulmonary disease (COPD)
Drug of choice in acute asthmatic bronchospasm

A

Albuterol

Clinical applications

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14
Q

Salmeterol

Clinical applications

A

Asthma prophylaxis

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15
Q

Asthma prophylaxis

A

Salmeterol

Clinical applications

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16
Q

Albuterol

Toxicity

A

Tremor
Tachycardia
Overdose: arrhythmias

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17
Q

Tremor
Tachycardia
Overdose: arrhythmias

A

Albuterol
Salmeterol

Toxicity

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18
Q

Salmeterol

Toxicity

A

Tremor
Tachycardia
Overdose: arrhythmias

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19
Q

Epinephrine

A

Nonselective Alpha and Beta agonist

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20
Q

Nonselective Alpha and Beta agonist

A

Epinephrine

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21
Q

Epinephrine

Mechanism of action

A

Nonselective Alpha and Beta agonist

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22
Q

Epinephrine

Effects

A

Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems

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23
Q

Bronchodilation plus all other sympathomimetic effects on cardiovascular and other organ systems

A

Epinephrine

Effects

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24
Epinephrine | Clinical applications
Anaphylaxis Asthma (Others) Rarely used for asthma (Beta2-selective agents preferred)
25
Anaphylaxis Asthma (Others) Rarely used for asthma (Beta2-selective agents preferred)
Epinephrine | Clinical applications
26
Isoproterenol
Beta1 and Beta2 agonist
27
Beta1 and Beta2 agonist
Isoproterenol
28
Isoproterenol | Mechanism of action
Beta1 and Beta2 agonist
29
Isoproterenol | Effects
Bronchodilation plus powerful cardiovascular effects
30
Bronchodilation plus powerful cardiovascular effects
Isoproterenol | Effects
31
Isoproterenol | Clinical applications
Asthma (but Beta2-selective agents preferred)
32
Asthma (but Beta2-selective agents preferred)
Isoproterenol | Clinical applications
33
Corticosteroids, inhaled
Fluticasone Beclomethasone Budesonide Flunisolide
34
Fluticasone
Corticosteroid, inhaled
35
Beclomethasone
Corticosteroid, inhaled
36
Budesonide
Corticosteroid, inhaled
37
Flunisolide
Corticosteroid, inhaled
38
Corticosteroids, inhaled | Mechanism of action
Alters gene expression
39
Corticosteroids, inhaled | Mechanism of action
Alters gene expression
40
Alters gene expression
Corticosteroids, inhaled Corticosteriods, systemic Mechanism of action
41
Corticosteroids, systemic | Mechanism of action
Alters gene expression
42
Fluticasone | Mechanism of action
Alters gene expression
43
Budesonide | Mechanism of action
Alters gene expression
44
Beclomethasone | Mechanism of action
Alters gene expression
45
Corticosteriods, inhaled | Effects
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
46
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
Corticosteriods, systemic Effects
47
Corticosteriods, systemic | Effects
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
48
Prednisone | Effects
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
49
Methylprednisolone | Effects
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
50
Betclomethasone | Effects
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
51
Budesonide | Effects
Reduces mediators of inflammation | Powerful prophylaxis of exacerbations
52
Corticosteroids, inhaled | Clinical applications
Asthma Adjunct in COPD Hay fever (nasal)
53
Asthma Adjunct in COPD Hay fever (nasal)
Corticosteroids, inhaled | Clinical applications
54
Corticosteroids, systemic | Clinical applications
Asthma | Adjunct in COPD
55
Asthma | Adjunct in COPD
Corticosteroids, systemic | Clinical applications
56
Corticosteroids
``` Fluticasone Beclomethasone Budesonide Flunisolide Prednisone Methylprednisolone ```
57
``` Fluticasone Beclomethasone Budesonide Flunisolide Prednisone Methylprednisolone ```
Corticosteroids
58
Stabilizers of mast and other cells
Cromolyn | Nedocromil
59
Cromolyn
Stabilizers of mast and other cells
60
Nedocromil
Stabilizers of mast and other cells
61
Nedocromil Cromolyn Mechanism of action
Alter function of delayed chloride channels | Inhibits inflammatory cell activation
62
Alter function of delayed chloride channels | Inhibits inflammatory cell activation
Nedocromil Cromolyn Mechanism of action
63
Nedocromil Cromolyn Effects
Prevents acute bronchospasm
64
Prevents acute bronchospasm
Nedocromil Cromolyn Effects
65
Nedocromil Cromolyn Clinical applications
Asthma | other routes used for ocular, nasal ang GI allergy
66
Asthma | other routes used for ocular, nasal ang GI allergy
Nedocromil Cromolyn Clinical applications
67
Methylxanthine
Theophylline
68
Theophylline
Methylxanthine
69
Theophylline | Mechanism of action
Uncertain Phosphodiesterase inhibition Adenosine receptor antagonist
70
Uncertain Phosphodiesterase inhibition Adenosine receptor antagonist
Theophylline | Mechanism of action
71
Theophylline | Effects
Bronchodilation Cardiac stimulation Increased skeletal muscle strength (diaphragm)
72
Bronchodilation Cardiac stimulation Increased skeletal muscle strength (diaphragm)
Theophylline | Effects
73
Theophylline | Clinical applications
Asthma | COPD
74
Asthma | COPD
Theophylline | Clinical applications
75
Leukotriene antagonists
Montelukast | Zafirlukast
76
Montelukast
Leukotriene antagonist
77
Zafirlukast
Leukotriene antagonist
78
Montelukast | Mechanism of action
Block leukotriene D4 receptors
79
Block leukotriene D4 receptors
Montelukast Zafirlukast Mechanism of action
80
Montelukast | Effects
Block airway response to exercise and antigen challange
81
Block airway response to exercise and antigen challange
Montelukast Zafirlukast Effects
82
Montelukast | Clinical applications
Prophylaxis of asthma especially in children and in aspirine-induced asthma
83
Prophylaxis of asthma especially in children and in aspirine-induced asthma
Montelukast Zafirlukast Clinical applications
84
IgE antibody
Omalizumab
85
Omalizumab
IgE antibody
86
Omalizumab | Mechanism of action
Humanized IgE antibody reduces circulating IgE
87
Humanized IgE antibody reduces circulating IgE
Omalizumab | Mechanism of action
88
Omalizumab | Effects
Reduces frequency of asthma exacerbaration
89
Omalizumab | Clinical application
Severe asthma inadequatly controlled by other agents

Pharma (29 decks)

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