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Pharma > Exam > Flashcards

Exam Flashcards

0
Q

A: antiviral
B: blocks DNA synthesis in virus infected cells
C: HSV-1, HSV-2

A

Acyclovir

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1
Q

Acyclovir

A

A: antiviral
B: blocks DNA synthesis in virus infected cells
C: HSV-1, HSV-2

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2
Q

Alendronate

A

A: bisphosphonate
B:suppress the activity of osteoclast in part via inhibithion of farnesyl pyrophosphate synthesis, inhibit bone resorbtion
C: osteoporosis, bone metastases, hypercalcemia

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3
Q

A: bisphosphonate
B:suppress the activity of osteoclast in part via inhibithion of farnesyl pyrophosphate synthesis, inhibit bone resorbtion
C: osteoporosis, bone metastases, hypercalcemia

A

Alendronate

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4
Q

Aminophylline

A

A: methylxanthine
B: phosphodiesterase inhibition, adenosin receptor antagonist, leads to bronchodialation, cardiac stimulation and increased skeletal muscle strength(diaphragm)
C: asthma, COPD

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5
Q

A: methylxanthine
B: phosphodiesterase inhibition, adenosin receptor antagonist, leads to bronchodialation, cardiac stimulation and increased skeletal muscle strength(diaphragm)
C: asthma, COPD

A

Aminophylline

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6
Q

Amitriptyline

A

A: tricyclic antidepessant (TCA)
B: mixed and variable blockade of NET and SERT
C: major depression not responsive to other drugs

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7
Q

A: tricyclic antidepessant (TCA)
B: mixed and variable blockade of NET and SERT
C: major depression not responsive to other drugs

A

Amitriptyline

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8
Q

Amlodipine

A

A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina

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9
Q

A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina

A

Amlodipine

Nifedipine

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10
Q

Nifedipine

A

A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina

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11
Q

Amoxicillin/Clavulanic acid

A

A: Beta-lactam antibiotics(penicillin) + Beta- lactamase inhibitor
B: synergistic activity against beta-lactamase-producing bacteria
C: gram-positive and gram-negative bacteria

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12
Q

A: Beta-lactam antibiotics(penicillin) + Beta- lactamase inhibitor
B: synergistic activity against beta-lactamase-producing bacteria
C: gram-positive and gram-negative bacteria

A

Amoxicillin/Clavulanic acid

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13
Q

Aripiprazole

A

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in major depression)

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14
Q

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in major depression)

A

Aripiprazole

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15
Q

Quetiapine

A

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms

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16
Q

Risperidone

A

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in bipolar disorder)

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17
Q

A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms

A

Aripiprazole
Quetiapine
Risperidone

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18
Q

Atorvastatin

A

A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome

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19
Q

A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome

A

Atorvastatin

Rosuvastatin

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20
Q

Rosuvastatin

A

A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome

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21
Q

Atovaquone-proguanil (Malarone)

A

A: antimalarial drug (quinone-folate antagonist combination)
B: blood schizonticides
C: treatment and chemoprophylaxis of P falciparum infection

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22
Q

A: antimalarial drug (quinone-folate antagonist combination)
B: blood schizonticides
C: treatment and chemoprophylaxis of P falciparum infection

A

Atovaquone-proguanil (Malarone)

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23
Q

Atropine

A

A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning

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24
Q

A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning

A

Atropine

Tropicamide

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25
Q

Benzylpenicillin

A

A: long acting, intramuscular penicillin
B: inhibit transpetidase
C: gram-positive cocci

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26
Q

A: long acting, intramuscular penicillin
B: inhibit transpetidase
C: gram-positive cocci

A

Benzylpenicillin

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27
Q

Bevacizumab

A

A: anticancer drug
B: inhibits VEGF signaling, inhibit tumor vascular permability
C: colerectal cancer

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28
Q

A: anticancer drug
B: inhibits VEGF signaling, inhibit tumor vascular permability
C: colerectal cancer

A

Bevacizumab

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29
Q

Bisoprolol

A

A: antihypertensive drug
B: Beta-1 selective blocker
C: hypertension

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30
Q

A: antihypertensive drug
B: Beta-1 selective blocker
C: hypertension

A

Bisoprolol

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31
Q

Bupivacaine

A

A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic

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32
Q

A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic

A

Bupivacaine

Lidocaine

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33
Q

Carbamazepine

A

A: antiseizure drug (tricyclic)
B: blockes high-frequency firing of neuron through action of VG Na+ channels, decreases synaptic relese of glutemate
C: generalized tonic-clonic seizures

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34
Q

A: antiseizure drug (tricyclic)
B: blockes high-frequency firing of neuron through action of VG Na+ channels, decreases synaptic relese of glutemate
C: generalized tonic-clonic seizures

A

Carbamazepine

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35
Q

Ceftriaxone

A

A: third-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: many uses including pneumonia, meningitis, pyelonephritis, and gonorrhea

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36
Q

A: third-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: many uses including pneumonia, meningitis, pyelonephritis, and gonorrhea

A

Ceftriaxone

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37
Q

Cephalexin

A

A: first-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: skin and soft tissue infection and urinary tract infections

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38
Q

A: first-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: skin and soft tissue infection and urinary tract infections

A

Cephalexin

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39
Q

Ciprofloxacin

A

A: fluoroquinolone
B: inhibits DNA replication by binding to DNA gyrase and topoisomerase IV
C: urinary tract infections, gastroenteritis, osteomyelitis, antrax

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40
Q

A: fluoroquinolone
B: inhibits DNA replication by binding to DNA gyrase and topoisomerase IV
C: urinary tract infections, gastroenteritis, osteomyelitis, antrax

A

Ciprofloxacin

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41
Q

Lidocaine

A

A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic

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42
Q

Clarithromycin

A

A: macrolide
B: prevents bacterial protein synthesis by binding to the 50s ribosomal subunit
C: M avium complex

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43
Q

A: macrolide
B: prevents bacterial protein synthesis by binding to the 50s ribosomal subunit
C: M avium complex

A

Clarithromycin

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44
Q

Clomiphene

A

A: ovulation-inducing agent
B: partial agonist at estrogen receptors, causing a surge og gonadotropins which leads to ovulation
C: treatment for women with ovulation disorders who wish to become pregnant

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45
Q

A: ovulation-inducing agent
B: partial agonist at estrogen receptors, causing a surge og gonadotropins which leads to ovulation
C: treatment for women with ovulation disorders who wish to become pregnant

A

Clomiphene

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46
Q

Clondine

A

A: sympathoplegics, centrally acting drug
B: activate Alpha-2 adrenoceptors
C: hypertension

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47
Q

A: sympathoplegics, centrally acting drug
B: activate Alpha-2 adrenoceptors
C: hypertension

A

Clondine

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48
Q

Clopidogrel

A

A: antiplatelet agent
B: irreversible block the ADO receptor on platelets
C: prevents thrombosis after placement of coronary stent

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49
Q

A: antiplatelet agent
B: irreversible block the ADO receptor on platelets
C: prevents thrombosis after placement of coronary stent

A

Clopidogrel

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50
Q

Clotrimazole

A

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: topical treatment of Candida

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51
Q

A: antifungal agent (imidazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: topical treatment of Candida

A

Clotrimazole

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52
Q

Fluconazole

A

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: excellent CNS penetration, used in fungal meningitis

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53
Q

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: excellent CNS penetration, used in fungal meningitis

A

Fluconazole

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54
Q

Itraconazole

A

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: broad spectrum: Candida, Cryptococcus, blastomycosis, etc

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55
Q

A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: broad spectrum: Candida, Cryptococcus, blastomycosis, etc

A

Itraconazole

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56
Q

Dabigatran

A

A: anticoagulant agent
B: oral direct thrombin inhibitor
C: prevention of venous thromboembolism, after hipnreplacement surgery

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57
Q

A: anticoagulant agent
B: oral direct thrombin inhibitor
C: prevention of venous thromboembolism, after hipnreplacement surgery

A

Dabigatran

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58
Q

Desmopressin

A

A: vasopressin receptor agonist
B: relatively selective vasopressin V-2 receptor agonist, decrease the excretion of water in kidney, also acts on extra renal V-2 receptors to increase factor Vlll and von Willebrand factor
C: hemophilia A and von Willebrand factor

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59
Q

A: vasopressin receptor agonist
B: relatively selective vasopressin V-2 receptor agonist, decrease the excretion of water in kidney, also acts on extra renal V-2 receptors to increase factor Vlll and von Willebrand factor
C: hemophilia A and von Willebrand factor

A

Desmopressin

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60
Q

Dextromethorphan

A

A: antitussive
B: strong and partial u-agonist, reduces cough reflex
C: acute debilitating cough

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61
Q

A: antitussive
B: strong and partial u-agonist, reduces cough reflex
C: acute debilitating cough

A

Dextromethorphan

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62
Q

Diazepam

A

A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states

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63
Q

A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states

A

Diazepam

Midazolam

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64
Q

Midazolam

A

A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states

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65
Q

Diclofenac

A

A: NSAID
B: nonselective cox inhibitor
C: prevntion of inflamation

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66
Q

A: NSAID
B: nonselective cox inhibitor
C: prevntion of inflamation

A

Diclofenac

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67
Q

Digoxin

A

A: cardiac glycoside
B: Na+\K+ ATPase inhibition result in reduced Ca2+ expulsion and increased Ca2+ stored in SR, increases contractility, slowes sinus HR, slowed atrioventricular conduction
C:chronic symptomatic heart failure

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68
Q

A: cardiac glycoside
B: Na+\K+ ATPase inhibition result in reduced Ca2+ expulsion and increased Ca2+ stored in SR, increases contractility, slowes sinus HR, slowed atrioventricular conduction
C:chronic symptomatic heart failure

A

Digoxin

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69
Q

Diltazem

A

A: calcium channel blockers
B: nonselective block of L-type calcium channels in vessels and heart, reduces vascular resistance, cardiac rate, and cardiac force result in decreased oxygen demand
C: prophylaxis of angina, hypertension, others

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70
Q

A: calcium channel blockers
B: nonselective block of L-type calcium channels in vessels and heart, reduces vascular resistance, cardiac rate, and cardiac force result in decreased oxygen demand
C: prophylaxis of angina, hypertension, others

A

Diltazem

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71
Q

Dinoprostone

A

A: synthetic PGE2
B: stimulates contraction of the uterus
C: softening of the cervix at term

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72
Q

A: synthetic PGE2
B: stimulates contraction of the uterus
C: softening of the cervix at term

A

Dinoprostone

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73
Q

Latanoprost

A

A: long acting PGF2a derivative
B: acts at FP receptor
C: glaucoma

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74
Q

A: long acting PGF2a derivative
B: acts at FP receptor
C: glaucoma

A

Latanoprost

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75
Q

Dobutamine

A

A: Beta 1 agonist
B: positive inotropic effect
C: cardiogenic shock,macute heart failure

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76
Q

A: Beta 1 agonist
B: positive inotropic effect
C: cardiogenic shock,macute heart failure

A

Dobutamine

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77
Q

Doxazosin

A

A: Alpha-adrenoceptor antagonist
B: blocks Alpha-1, but not Alpha-2, lower BP
C: hypertension, benign prostatic hyperplasia

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78
Q

A: Alpha-adrenoceptor antagonist
B: blocks Alpha-1, but not Alpha-2, lower BP
C: hypertension, benign prostatic hyperplasia

A

Doxazosin

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79
Q

Doxorubicin

A

A: Anthracycline, Cytotoxic antcancer drug
B: Inhibits topoisomerase II, bind DNA, free radical production, bind cellular membranes
C: used as single agent or in combination

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80
Q

A: Anthracycline, Cytotoxic antcancer drug
B: Inhibits topoisomerase II, bind DNA, free radical production, bind cellular membranes
C: used as single agent or in combination

A

Doxorubicin

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81
Q

Doxycycline

A

A: Tetracycline
B: Prevents bacterial protein synthesis by binding to the 30S ribosomal subunit, bacteriostatic activity
C: chlamydia, mycoplasma, spirochetes, etc

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82
Q

A: Tetracycline
B: Prevents bacterial protein synthesis by binding to the 30S ribosomal subunit, bacteriostatic activity
C: chlamydia, mycoplasma, spirochetes, etc

A

Doxycycline

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83
Q

Enoxaparine

A

A: LMW heparin
B: accelerates the action of antithrombin 1000-fold
C: prevention of venous trombosis

84
Q

A: LMW heparin
B: accelerates the action of antithrombin 1000-fold
C: prevention of venous trombosis

A

Enoxaparine

85
Q

Escitalopram

A

A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression

86
Q

A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression

A

Escitalopram

Paroxetine

87
Q

Ezetimibe

A

A: sterol absorption inhibitor
B: blockes sterol transporter NPC1L1 in intestine bruch border, inhibits reabsorption of cholesterol excreted in bile, decreases LDL and phytosterols
C: elevated LDL, phytosterolemia

88
Q

A: sterol absorption inhibitor
B: blockes sterol transporter NPC1L1 in intestine bruch border, inhibits reabsorption of cholesterol excreted in bile, decreases LDL and phytosterols
C: elevated LDL, phytosterolemia

A

Ezetimibe

89
Q

Finasteride

A

A: 5a- reductase inhibitor
B: Blocks conversion of dihydrotestosteron
C: benign prostatic hyperplasia

90
Q

A: 5a- reductase inhibitor
B: Blocks conversion of dihydrotestosteron
C: benign prostatic hyperplasia

A

Finasteride

91
Q

Fluorouracil

A

A: Fluoropyrimidine
B: Anti-metabolite, interferes with DNA and RNA syntesis
C: Most widely used agent in the treatment of colorectal cancer

92
Q

A: Fluoropyrimidine
B: Anti-metabolite, interferes with DNA and RNA syntesis
C: Most widely used agent in the treatment of colorectal cancer

A

Fluorouracil

93
Q

Furosemide

A

A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle’s loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc

94
Q

A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle’s loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc

A

Furosemide

Torasemide

95
Q

Haloperidol

A

A: typical antipsychotic (butyrophenone)
B: blockade of D2 receptors&raquo_space; 5-HT2a receptors
C: schizophrenia (positive symptoms)

96
Q

A: typical antipsychotic (butyrophenone)
B: blockade of D2 receptors&raquo_space; 5-HT2a receptors
C: schizophrenia (positive symptoms)

A

Haloperidol

97
Q

Hydrochlorothiazide

A

A: thiazide diuretic
B: Inhibition of the Na/Cl transporter in the distal convoluted tubule, modest increase in NaCl excretion
C: hypertension, mild heart failure

98
Q

A: thiazide diuretic
B: Inhibition of the Na/Cl transporter in the distal convoluted tubule, modest increase in NaCl excretion
C: hypertension, mild heart failure

A

Hydrochlorothiazide

99
Q

Infliximab

A

A: Human-mouse chineric IgG1 monoclonial antibody
B:Bind TNF-a, ( a proinflamatory cytokine importent in inflammatory diseases)
C: rheumatoid arthritis

100
Q

A: Human-mouse chineric IgG1 monoclonial antibody
B:Bind TNF-a, ( a proinflamatory cytokine importent in inflammatory diseases)
C: rheumatoid arthritis

A

Infliximab

101
Q

Insulin lispro

A

A: rapid-acting insuline
B: activate insulin receptor
C: type 1 and type 2 diabetes

102
Q

A: rapid-acting insuline
B: activate insulin receptor
C: type 1 and type 2 diabetes

A

Insulin lispro

103
Q

Irbesartan

A

A: antihypertensive agent (ARB)
B: block AT-1 angiotensin receptors
C: hypertension, heart failure

104
Q

A: antihypertensive agent (ARB)
B: block AT-1 angiotensin receptors
C: hypertension, heart failure

A

Irbesartan

105
Q

Isoniazid

A

A: antimycobacterial drug
B: inhibit synthesis of mycolic acid, an essential component of mycobacterial cell walls, bactericidal against susceptible strains of M tuberculosis
C: first-line treatment against tuberculosis

106
Q

A: antimycobacterial drug
B: inhibit synthesis of mycolic acid, an essential component of mycobacterial cell walls, bactericidal against susceptible strains of M tuberculosis
C: first-line treatment against tuberculosis

A

Isoniazid

107
Q

Rifampin

A

A: antimycobacterial drug
B: inhibits DNA- dependent RNA polymerase, thereby blocking production of RNA
C: tuberculosis, atypical mycobacterial infections

108
Q

A: antimycobacterial drug
B: inhibits DNA- dependent RNA polymerase, thereby blocking production of RNA
C: tuberculosis, atypical mycobacterial infections

A

Rifampin

109
Q

Isotretinoin

A

A: synthetic retinoid
B: inhibit sebaceous gland size and function
C: severe cystic acne

110
Q

A: synthetic retinoid
B: inhibit sebaceous gland size and function
C: severe cystic acne

A

Isotretinoin

111
Q

Isosorbide mononitrate

A

A: nitrate
B: Releases nitric oxide in smooth muscle, whitch activates guanylyl cyclase and increases cGMP, leads to smooth muscle relaxation especially in vessels
C: angina, acute coronary syndrome

112
Q

A: nitrate
B: Releases nitric oxide in smooth muscle, whitch activates guanylyl cyclase and increases cGMP, leads to smooth muscle relaxation especially in vessels
C: angina, acute coronary syndrome

A

Isosorbide mononitrate

113
Q

Levodopa/benserazide

A

A: antiparkinsom drug
B: transported into CNS and coverted to dopamine, ameliorates all symptoms of parkinson’s disease
C: parkingsons disease

114
Q

A: antiparkinsom drug
B: transported into CNS and coverted to dopamine, ameliorates all symptoms of parkinson’s disease
C: parkingsons disease

A

Levodopa/benserazide

115
Q

Levonorgestrel

A

A:

116
Q

Mebendazole

A

A: antihelminthic drug
B: inhibiting microtubule synthesis
C: ascariasis, trichuriasis, hookworm and pinworm infection

117
Q

A: antihelminthic drug
B: inhibiting microtubule synthesis
C: ascariasis, trichuriasis, hookworm and pinworm infection

A

Mebendazole

118
Q

Memantine

A

A: cognetive enhancer
B: NMDA receptor channel blocker
C: alzheimer’s disease

119
Q

A: cognetive enhancer
B: NMDA receptor channel blocker
C: alzheimer’s disease

A

Memantine

120
Q

Metformin

A

A: biguanides
B: reduced hepatic and renal gluconeogenesis, decreases endogenous glucose production
C: type 2 diabetes

121
Q

A: biguanides
B: reduced hepatic and renal gluconeogenesis, decreases endogenous glucose production
C: type 2 diabetes

A

Metformin

122
Q

Methotrexate

A

A: Disease-modifying antirheumatic drug
B: synthetic antimetabolite, acumulates intracellularly, inhibits AMP deaminase, acumulates AMP, leads to less inflamaton
C: rheumatoid arthritis

123
Q

A: Disease-modifying antirheumatic drug
B: synthetic antimetabolite, acumulates intracellularly, inhibits AMP deaminase, acumulates AMP, leads to less inflamaton
C: rheumatoid arthritis

A

Methotrexate

124
Q

Metronidazole

A

A: miscellaneous antimicrobial
B: disruption of electron transport chain, bactericidal against anaerobic bacteria and protozoa
C: C difficile colitis

125
Q

A: miscellaneous antimicrobial
B: disruption of electron transport chain, bactericidal against anaerobic bacteria and protozoa
C: C difficile colitis

A

Metronidazole

126
Q

Metoprolol

A

A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension

127
Q

A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension

A

Metoprolol

Nebivolol

128
Q

Montelukast

A

A: Leukotriene antagonist
B: blocks leukotriene D4 receptor, block airway responce to exercise and antigen challenge
C: prophylaxis of asthma

129
Q

A: Leukotriene antagonist
B: blocks leukotriene D4 receptor, block airway responce to exercise and antigen challenge
C: prophylaxis of asthma

A

Montelukast

130
Q

Methylprednisolone

A

A: corticosteroid, systemic
B: alters gene expression, reduces mediators of inflammation
C: asthma

131
Q

A: corticosteroid, systemic
B: alters gene expression, reduces mediators of inflammation
C: asthma

A

Methylprednisolone

132
Q

Morphine

A

A: strong opioid agonist
B: strong u-receptor agonist, analgesia, relif of anxiety, sedation, slowes gastrointestinal transit
C: severe pain, adjunct in anesthesia, pulmonary edema

133
Q

A: strong opioid agonist
B: strong u-receptor agonist, analgesia, relif of anxiety, sedation, slowes gastrointestinal transit
C: severe pain, adjunct in anesthesia, pulmonary edema

A

Morphine

134
Q

Nebivolol

A

A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension

135
Q

Omeprazole

A

A: proton pump inhibitor
B: Irreversible blockade of H+/K+ATPase pump in active parietal cells of stomach, long-lasting reduction of stimulated and nocturnal acid secration
C: peptic ulcer disease

136
Q

A: proton pump inhibitor
B: Irreversible blockade of H+/K+ATPase pump in active parietal cells of stomach, long-lasting reduction of stimulated and nocturnal acid secration
C: peptic ulcer disease

A

Omeprazole

137
Q

Ondansetron

A

A: antiemetic drug
B: 5-HT3 blockade in gut and CNS, Extremely effective in preventing chemotheraphy induced and postoperative nausea and vomiting
C: postoperative emesis

138
Q

A: antiemetic drug
B: 5-HT3 blockade in gut and CNS, Extremely effective in preventing chemotheraphy induced and postoperative nausea and vomiting
C: postoperative emesis

A

Ondansetron

139
Q

Oseltamivir

A

A: antiviral agent
B: neuramidase inhibitor, interfere with the release of progeny influenca virus from infected host cell, halting spread of infection
C: influenza

140
Q

A: antiviral agent
B: neuramidase inhibitor, interfere with the release of progeny influenca virus from infected host cell, halting spread of infection
C: influenza

A

Oseltamivir

141
Q

Oxytocin

A

A: pituitary hormone
B: activates oxytocin receptor, increases uterine contractions
C: induction of labor

142
Q

A: pituitary hormone
B: activates oxytocin receptor, increases uterine contractions
C: induction of labor

A

Oxytocin

143
Q

Pancreatin

A

A: pancreatic supplement
B: replaces enzymes from animal extracts, improves digestion of diatary fat, protein, and carbohydrates
C: pancreatetomy

144
Q

A: pancreatic supplement
B: replaces enzymes from animal extracts, improves digestion of diatary fat, protein, and carbohydrates
C: pancreatetomy

A

Pancreatin

145
Q

Paroxetine

A

A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression

146
Q

Perindopril

A

A: angiotensin-coverting enzyme inhibitor
B: inhibit angiotensin converting enzyme, reduces vasoconstriction and aldosteron secretion
C: heart failure

147
Q

A: angiotensin-coverting enzyme inhibitor
B: inhibit angiotensin converting enzyme, reduces vasoconstriction and aldosteron secretion
C: heart failure

A

Perindopril

148
Q

Permethrin

A

A: dermatologic application
B: ectoparasiticide
C: scabis

149
Q

A: dermatologic application
B: ectoparasiticide
C: scabis

A

Permethrin

150
Q

Povidone iodine

A

A: halogen
B: kill bacteria, fungi and lipid viruses
C: antiseptic

151
Q

A: halogen
B: kill bacteria, fungi and lipid viruses
C: antiseptic

A

Povidone iodine

152
Q

Procainamide

A

A: class 1A antiarrhythmic
B: slowes conduction velocity and pacemaker rate
C: atrial arrhytmias

153
Q

A: class 1A antiarrhythmic
B: slowes conduction velocity and pacemaker rate
C: atrial arrhytmias

A

Procainamide

154
Q

Propranolol

A 
A: class 2 antiarrhythmic
B: Beta-adrenoceptor blockade slows AV node automatisity and AV nodal conduction velocity
C: prevention of sudden death
155
Q 
A: class 2 antiarrhythmic
B: Beta-adrenoceptor blockade slows AV node automatisity and AV nodal conduction velocity
C: prevention of sudden death
A

Propranolol

156
Q

Ranitidine

A

A: H2 blocker
B: blocks H2, reduces nocturnal acid secration
C: acid reflux

157
Q

A: H2 blocker
B: blocks H2, reduces nocturnal acid secration
C: acid reflux

A

Ranitidine

158
Q

Rivaroxaban

A

A: anticoagulant
B: direct factor Xa inhibitor
C:prevebtion of venous thrombolism

159
Q

A: anticoagulant
B: direct factor Xa inhibitor
C:prevebtion of venous thrombolism

A

Rivaroxaban

160
Q

Sildenafil

A

A: phosphodiesterase inhibitor
B: incrases cGMP, leads to relaxation of smooth muscles
C: erectile dysfunction

161
Q

A: phosphodiesterase inhibitor
B: incrases cGMP, leads to relaxation of smooth muscles
C: erectile dysfunction

A

Sildenafil

162
Q

Spironolactone

A

A: potassium-sparing diuretic
B: Pharmacologic antagonist of aldosteron in collecting tubules, Weak antagonism of androgen receptor, reduces Na retension
C: postmyocardial infection

163
Q

A: potassium-sparing diuretic
B: Pharmacologic antagonist of aldosteron in collecting tubules, Weak antagonism of androgen receptor, reduces Na retension
C: postmyocardial infection

A

Spironolactone

164
Q

Tamsulosin

A

A: sympathetic antagonists
B: slightly selective for Alpha-1A, blockade of prostaic smooth muscle more the vascular smooth muscle
C: benign prostatic hyperplasia

165
Q

A: sympathetic antagonists
B: slightly selective for Alpha-1A, blockade of prostaic smooth muscle more the vascular smooth muscle
C: benign prostatic hyperplasia

A

Tamsulosin

166
Q

Terbinafine

A

A: antifungal
B: inhibits epoxidation of squalene in fungi, increased levels are toxic to them, reduces ergosterol
C: mucocutaneoys fungsl infection

167
Q

A: antifungal
B: inhibits epoxidation of squalene in fungi, increased levels are toxic to them, reduces ergosterol
C: mucocutaneoys fungsl infection

A

Terbinafine

168
Q

Tolterodine

A

A: antimuscarinic agent
B: M-3 selective block
C: urinary incontinence

169
Q

A: antimuscarinic agent
B: M-3 selective block
C: urinary incontinence

A

Tolterodine

170
Q

Torasemide

A

A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle’s loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc

171
Q

Trihexyphenidyl

A

A: antimuscarinic agent
B: antagonist at M receptors in basal ganglia, reduces tremor and rgidity
C: parkingson’s disease

172
Q

A: antimuscarinic agent
B: antagonist at M receptors in basal ganglia, reduces tremor and rgidity
C: parkingson’s disease

A

Trihexyphenidyl

173
Q

Tropicamide

A

A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning

174
Q

Valproate acid

A

A: antiseizure drug
B: blocks high-frequency firing of neuron, modifies amino acid metabolism
C: myoclonic seizures

175
Q

A: antiseizure drug
B: blocks high-frequency firing of neuron, modifies amino acid metabolism
C: myoclonic seizures

A

Valproate acid

176
Q

Warfarin

A

A: anticoagulant
B: cause blockad of y-carboxylation of several endogenous produced coagulation factors, making the biological inactive
C: DVT profylaxis

177
Q

A: anticoagulant
B: cause blockad of y-carboxylation of several endogenous produced coagulation factors, making the biological inactive
C: DVT profylaxis

A

Warfarin

178
Q

Zolmitriptan

A

A: anti migrane drug (triptan)
B: 5-HT(1D/1B) agonist
C: migrane

179
Q

A: anti migrane drug (triptan)
B: 5-HT(1D/1B) agonist
C: migrane

A

Zolmitriptan

180
Q

Zolpidem

A

A: newer hypnotic
B: bind selectivly to a subunit og GABA(A) acting like benzodiasapines, rapid onset of hypnosis
C: sleep disorders

181
Q

A: newer hypnotic
B: bind selectivly to a subunit og GABA(A) acting like benzodiasapines, rapid onset of hypnosis
C: sleep disorders

A

Zolpidem

182
Q

Salbutamol

A

A: selective Beta2 agonist
B: prompt, efficacious broncodialation
C: acute asthmatic broncospasm

183
Q

A: selective Beta2 agonist
B: prompt, efficacious broncodialation
C: acute asthmatic broncospasm

A

Salbutamol

184
Q

Physostigmine

A

A: intermediate-acting cholinesterase inhibitor
B: blocks AChE
C: myastavia gravis

185
Q

A: intermediate-acting cholinesterase inhibitor
B: blocks AChE
C: myastavia gravis

A

Physostigmine

186
Q

Ursodeoxycholic acid

A

A: bile acid theraphy drug
B: reduces cholesterol secration into bile, dissolve gallstones,
C: gallstone

187
Q

A: bile acid theraphy drug
B: reduces cholesterol secration into bile, dissolve gallstones,
C: gallstone

A

Ursodeoxycholic acid

188
Q

Loratadine

A

A: second-generation H1 blocker
B: blocks H1 receptors, prevents releace of histamine
C: hey fever

189
Q

A: second-generation H1 blocker
B: blocks H1 receptors, prevents releace of histamine
C: hey fever

A

Loratadine

190
Q

Etoricoxib

A

A: NSAID
B: cox-2 selective inhibitor
C: block peripheral inflamation

191
Q

A: NSAID
B: cox-2 selective inhibitor
C: block peripheral inflamation

A

Etoricoxib

192
Q

Ephedrine

A

A: agonist of alpha and beta
B: same as A
C: not used

193
Q

A: agonist of alpha and beta
B: same as A
C: not used

A

Ephedrine

194
Q

Levonorgestrel

A

A: synthetic progrestin
B: inhibit ovulation
C: morning after pil

195
Q

A: synthetic progrestin
B: inhibit ovulation
C: morning after pil

A

Levonorgestrel

196
Q

Mesalazine

A

A: antiinflamatory
B: inhibit eicosanoid inflamatory mediators
C: inflamatory bowel disease

197
Q

A: antiinflamatory
B: inhibit eicosanoid inflamatory mediators
C: inflamatory bowel disease

A

Mesalazine

198
Q

Piracetam

A

A: nootropic
B: increases cognitive function
C: dementia

199
Q

A: nootropic
B: increases cognitive function
C: dementia

A

Piracetam

200
Q

Adrenalin

A

A: catochlomamine
B: adrengenic agonist
C: hypotension

201
Q

A: catochlomamine
B: adrengenic agonist
C: hypotension

A

Adrenalin

202
Q

Acetylsalcylic acid

A

A: NSAID
B: cox inhibition
C: prevention of heart attack

203
Q

A: NSAID
B: cox inhibition
C: prevention of heart attack

A

Acetylsalcylic acid

204
Q

Amiodarone

A 
A: class 3 antiarrhytmic
B: bloks I(kr), I(Na), I(Ca-L), prolongs action potential an QT interval
C: serious ventricular arrhytmias
205
Q 
A: class 3 antiarrhytmic
B: bloks I(kr), I(Na), I(Ca-L), prolongs action potential an QT interval
C: serious ventricular arrhytmias
A

Amiodarone

206
Q

Co-triamaxazole

A

A: folate antagonist
B: Synergistic combination of folate antagonists blocks purine production and nucleic acid synthesis, bactericidal activity against susceptible bacteria
C: UTI

207
Q

A: folate antagonist
B: Synergistic combination of folate antagonists blocks purine production and nucleic acid synthesis, bactericidal activity against susceptible bacteria
C: UTI

A

Co-triamaxazole

Pharma (29 decks)

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