Exam Flashcards
0
Q
A: antiviral
B: blocks DNA synthesis in virus infected cells
C: HSV-1, HSV-2
A
Acyclovir
1
Q
Acyclovir
A
A: antiviral
B: blocks DNA synthesis in virus infected cells
C: HSV-1, HSV-2
2
Q
Alendronate
A
A: bisphosphonate
B:suppress the activity of osteoclast in part via inhibithion of farnesyl pyrophosphate synthesis, inhibit bone resorbtion
C: osteoporosis, bone metastases, hypercalcemia
3
Q
A: bisphosphonate
B:suppress the activity of osteoclast in part via inhibithion of farnesyl pyrophosphate synthesis, inhibit bone resorbtion
C: osteoporosis, bone metastases, hypercalcemia
A
Alendronate
4
Q
Aminophylline
A
A: methylxanthine
B: phosphodiesterase inhibition, adenosin receptor antagonist, leads to bronchodialation, cardiac stimulation and increased skeletal muscle strength(diaphragm)
C: asthma, COPD
5
Q
A: methylxanthine
B: phosphodiesterase inhibition, adenosin receptor antagonist, leads to bronchodialation, cardiac stimulation and increased skeletal muscle strength(diaphragm)
C: asthma, COPD
A
Aminophylline
6
Q
Amitriptyline
A
A: tricyclic antidepessant (TCA)
B: mixed and variable blockade of NET and SERT
C: major depression not responsive to other drugs
7
Q
A: tricyclic antidepessant (TCA)
B: mixed and variable blockade of NET and SERT
C: major depression not responsive to other drugs
A
Amitriptyline
8
Q
Amlodipine
A
A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina
9
Q
A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina
A
Amlodipine
Nifedipine
10
Q
Nifedipine
A
A: vasodialator (dihydropyridine)
B: block vascular calcium channels > cardiac calcium channels
C: hypertension, angina
11
Q
Amoxicillin/Clavulanic acid
A
A: Beta-lactam antibiotics(penicillin) + Beta- lactamase inhibitor
B: synergistic activity against beta-lactamase-producing bacteria
C: gram-positive and gram-negative bacteria
12
Q
A: Beta-lactam antibiotics(penicillin) + Beta- lactamase inhibitor
B: synergistic activity against beta-lactamase-producing bacteria
C: gram-positive and gram-negative bacteria
A
Amoxicillin/Clavulanic acid
13
Q
Aripiprazole
A
A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in major depression)
14
Q
A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in major depression)
A
Aripiprazole
15
Q
Quetiapine
A
A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms
16
Q
Risperidone
A
A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms (also in bipolar disorder)
17
Q
A: atypical antipsychotic
B: blockade of 5-HT2A receptors > blockade of D2 receptors
C: schizophrenia-improve both posetive and negative symtoms
A
Aripiprazole
Quetiapine
Risperidone
18
Q
Atorvastatin
A
A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome
19
Q
A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome
A
Atorvastatin
Rosuvastatin
20
Q
Rosuvastatin
A
A: Statin (HMG-CoA inhibitor)
B: inhibit HMG-CoA reductase, reduces cholesterol synthesis and up-regulate LDL receptors on hepatocytes
C: Atherosclerotic vascular disease, acute coronary syndrome
21
Q
Atovaquone-proguanil (Malarone)
A
A: antimalarial drug (quinone-folate antagonist combination)
B: blood schizonticides
C: treatment and chemoprophylaxis of P falciparum infection
22
Q
A: antimalarial drug (quinone-folate antagonist combination)
B: blood schizonticides
C: treatment and chemoprophylaxis of P falciparum infection
A
Atovaquone-proguanil (Malarone)
23
Q
Atropine
A
A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning
24
A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning
Atropine
| Tropicamide
25
Benzylpenicillin
A: long acting, intramuscular penicillin
B: inhibit transpetidase
C: gram-positive cocci
26
A: long acting, intramuscular penicillin
B: inhibit transpetidase
C: gram-positive cocci
Benzylpenicillin
27
Bevacizumab
A: anticancer drug
B: inhibits VEGF signaling, inhibit tumor vascular permability
C: colerectal cancer
28
A: anticancer drug
B: inhibits VEGF signaling, inhibit tumor vascular permability
C: colerectal cancer
Bevacizumab
29
Bisoprolol
A: antihypertensive drug
B: Beta-1 selective blocker
C: hypertension
30
A: antihypertensive drug
B: Beta-1 selective blocker
C: hypertension
Bisoprolol
31
Bupivacaine
A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic
32
A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic
Bupivacaine
| Lidocaine
33
Carbamazepine
A: antiseizure drug (tricyclic)
B: blockes high-frequency firing of neuron through action of VG Na+ channels, decreases synaptic relese of glutemate
C: generalized tonic-clonic seizures
34
A: antiseizure drug (tricyclic)
B: blockes high-frequency firing of neuron through action of VG Na+ channels, decreases synaptic relese of glutemate
C: generalized tonic-clonic seizures
Carbamazepine
35
Ceftriaxone
A: third-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: many uses including pneumonia, meningitis, pyelonephritis, and gonorrhea
36
A: third-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: many uses including pneumonia, meningitis, pyelonephritis, and gonorrhea
Ceftriaxone
37
Cephalexin
A: first-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: skin and soft tissue infection and urinary tract infections
38
A: first-generation cephalosporin
B: prevent bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases
C: skin and soft tissue infection and urinary tract infections
Cephalexin
39
Ciprofloxacin
A: fluoroquinolone
B: inhibits DNA replication by binding to DNA gyrase and topoisomerase IV
C: urinary tract infections, gastroenteritis, osteomyelitis, antrax
40
A: fluoroquinolone
B: inhibits DNA replication by binding to DNA gyrase and topoisomerase IV
C: urinary tract infections, gastroenteritis, osteomyelitis, antrax
Ciprofloxacin
41
Lidocaine
A: local anesthesia
B: blockade of sodium channels
C: spinal anesthetic
42
Clarithromycin
A: macrolide
B: prevents bacterial protein synthesis by binding to the 50s ribosomal subunit
C: M avium complex
43
A: macrolide
B: prevents bacterial protein synthesis by binding to the 50s ribosomal subunit
C: M avium complex
Clarithromycin
44
Clomiphene
A: ovulation-inducing agent
B: partial agonist at estrogen receptors, causing a surge og gonadotropins which leads to ovulation
C: treatment for women with ovulation disorders who wish to become pregnant
45
A: ovulation-inducing agent
B: partial agonist at estrogen receptors, causing a surge og gonadotropins which leads to ovulation
C: treatment for women with ovulation disorders who wish to become pregnant
Clomiphene
46
Clondine
A: sympathoplegics, centrally acting drug
B: activate Alpha-2 adrenoceptors
C: hypertension
47
A: sympathoplegics, centrally acting drug
B: activate Alpha-2 adrenoceptors
C: hypertension
Clondine
48
Clopidogrel
A: antiplatelet agent
B: irreversible block the ADO receptor on platelets
C: prevents thrombosis after placement of coronary stent
49
A: antiplatelet agent
B: irreversible block the ADO receptor on platelets
C: prevents thrombosis after placement of coronary stent
Clopidogrel
50
Clotrimazole
A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: topical treatment of Candida
51
A: antifungal agent (imidazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: topical treatment of Candida
Clotrimazole
52
Fluconazole
A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: excellent CNS penetration, used in fungal meningitis
53
A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: excellent CNS penetration, used in fungal meningitis
Fluconazole
54
Itraconazole
A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: broad spectrum: Candida, Cryptococcus, blastomycosis, etc
55
A: antifungal agent (triazole)
B: inhibit ergosterol synthesis, by inhibition of fungal cytochrome P450 enzymes
C: broad spectrum: Candida, Cryptococcus, blastomycosis, etc
Itraconazole
56
Dabigatran
A: anticoagulant agent
B: oral direct thrombin inhibitor
C: prevention of venous thromboembolism, after hipnreplacement surgery
57
A: anticoagulant agent
B: oral direct thrombin inhibitor
C: prevention of venous thromboembolism, after hipnreplacement surgery
Dabigatran
58
Desmopressin
A: vasopressin receptor agonist
B: relatively selective vasopressin V-2 receptor agonist, decrease the excretion of water in kidney, also acts on extra renal V-2 receptors to increase factor Vlll and von Willebrand factor
C: hemophilia A and von Willebrand factor
59
A: vasopressin receptor agonist
B: relatively selective vasopressin V-2 receptor agonist, decrease the excretion of water in kidney, also acts on extra renal V-2 receptors to increase factor Vlll and von Willebrand factor
C: hemophilia A and von Willebrand factor
Desmopressin
60
Dextromethorphan
A: antitussive
B: strong and partial u-agonist, reduces cough reflex
C: acute debilitating cough
61
A: antitussive
B: strong and partial u-agonist, reduces cough reflex
C: acute debilitating cough
Dextromethorphan
62
Diazepam
A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states
63
A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states
Diazepam
| Midazolam
64
Midazolam
A: benzodiazepne
B: Bind to specific GABA(A) receptor subunits at central nervous system (CNS) neuronal synapses facilitating frequency of GABA-mediated chloride ion channel opening- enhance membrane hyperpolarization
C: acute anxiety states
65
Diclofenac
A: NSAID
B: nonselective cox inhibitor
C: prevntion of inflamation
66
A: NSAID
B: nonselective cox inhibitor
C: prevntion of inflamation
Diclofenac
67
Digoxin
A: cardiac glycoside
B: Na+\K+ ATPase inhibition result in reduced Ca2+ expulsion and increased Ca2+ stored in SR, increases contractility, slowes sinus HR, slowed atrioventricular conduction
C:chronic symptomatic heart failure
68
A: cardiac glycoside
B: Na+\K+ ATPase inhibition result in reduced Ca2+ expulsion and increased Ca2+ stored in SR, increases contractility, slowes sinus HR, slowed atrioventricular conduction
C:chronic symptomatic heart failure
Digoxin
69
Diltazem
A: calcium channel blockers
B: nonselective block of L-type calcium channels in vessels and heart, reduces vascular resistance, cardiac rate, and cardiac force result in decreased oxygen demand
C: prophylaxis of angina, hypertension, others
70
A: calcium channel blockers
B: nonselective block of L-type calcium channels in vessels and heart, reduces vascular resistance, cardiac rate, and cardiac force result in decreased oxygen demand
C: prophylaxis of angina, hypertension, others
Diltazem
71
Dinoprostone
A: synthetic PGE2
B: stimulates contraction of the uterus
C: softening of the cervix at term
72
A: synthetic PGE2
B: stimulates contraction of the uterus
C: softening of the cervix at term
Dinoprostone
73
Latanoprost
A: long acting PGF2a derivative
B: acts at FP receptor
C: glaucoma
74
A: long acting PGF2a derivative
B: acts at FP receptor
C: glaucoma
Latanoprost
75
Dobutamine
A: Beta 1 agonist
B: positive inotropic effect
C: cardiogenic shock,macute heart failure
76
A: Beta 1 agonist
B: positive inotropic effect
C: cardiogenic shock,macute heart failure
Dobutamine
77
Doxazosin
A: Alpha-adrenoceptor antagonist
B: blocks Alpha-1, but not Alpha-2, lower BP
C: hypertension, benign prostatic hyperplasia
78
A: Alpha-adrenoceptor antagonist
B: blocks Alpha-1, but not Alpha-2, lower BP
C: hypertension, benign prostatic hyperplasia
Doxazosin
79
Doxorubicin
A: Anthracycline, Cytotoxic antcancer drug
B: Inhibits topoisomerase II, bind DNA, free radical production, bind cellular membranes
C: used as single agent or in combination
80
A: Anthracycline, Cytotoxic antcancer drug
B: Inhibits topoisomerase II, bind DNA, free radical production, bind cellular membranes
C: used as single agent or in combination
Doxorubicin
81
Doxycycline
A: Tetracycline
B: Prevents bacterial protein synthesis by binding to the 30S ribosomal subunit, bacteriostatic activity
C: chlamydia, mycoplasma, spirochetes, etc
82
A: Tetracycline
B: Prevents bacterial protein synthesis by binding to the 30S ribosomal subunit, bacteriostatic activity
C: chlamydia, mycoplasma, spirochetes, etc
Doxycycline
83
Enoxaparine
A: LMW heparin
B: accelerates the action of antithrombin 1000-fold
C: prevention of venous trombosis
84
A: LMW heparin
B: accelerates the action of antithrombin 1000-fold
C: prevention of venous trombosis
Enoxaparine
85
Escitalopram
A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression
86
A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression
Escitalopram
| Paroxetine
87
Ezetimibe
A: sterol absorption inhibitor
B: blockes sterol transporter NPC1L1 in intestine bruch border, inhibits reabsorption of cholesterol excreted in bile, decreases LDL and phytosterols
C: elevated LDL, phytosterolemia
88
A: sterol absorption inhibitor
B: blockes sterol transporter NPC1L1 in intestine bruch border, inhibits reabsorption of cholesterol excreted in bile, decreases LDL and phytosterols
C: elevated LDL, phytosterolemia
Ezetimibe
89
Finasteride
A: 5a- reductase inhibitor
B: Blocks conversion of dihydrotestosteron
C: benign prostatic hyperplasia
90
A: 5a- reductase inhibitor
B: Blocks conversion of dihydrotestosteron
C: benign prostatic hyperplasia
Finasteride
91
Fluorouracil
A: Fluoropyrimidine
B: Anti-metabolite, interferes with DNA and RNA syntesis
C: Most widely used agent in the treatment of colorectal cancer
92
A: Fluoropyrimidine
B: Anti-metabolite, interferes with DNA and RNA syntesis
C: Most widely used agent in the treatment of colorectal cancer
Fluorouracil
93
Furosemide
A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc
94
A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc
Furosemide
| Torasemide
95
Haloperidol
A: typical antipsychotic (butyrophenone)
B: blockade of D2 receptors >> 5-HT2a receptors
C: schizophrenia (positive symptoms)
96
A: typical antipsychotic (butyrophenone)
B: blockade of D2 receptors >> 5-HT2a receptors
C: schizophrenia (positive symptoms)
Haloperidol
97
Hydrochlorothiazide
A: thiazide diuretic
B: Inhibition of the Na/Cl transporter in the distal convoluted tubule, modest increase in NaCl excretion
C: hypertension, mild heart failure
98
A: thiazide diuretic
B: Inhibition of the Na/Cl transporter in the distal convoluted tubule, modest increase in NaCl excretion
C: hypertension, mild heart failure
Hydrochlorothiazide
99
Infliximab
A: Human-mouse chineric IgG1 monoclonial antibody
B:Bind TNF-a, ( a proinflamatory cytokine importent in inflammatory diseases)
C: rheumatoid arthritis
100
A: Human-mouse chineric IgG1 monoclonial antibody
B:Bind TNF-a, ( a proinflamatory cytokine importent in inflammatory diseases)
C: rheumatoid arthritis
Infliximab
101
Insulin lispro
A: rapid-acting insuline
B: activate insulin receptor
C: type 1 and type 2 diabetes
102
A: rapid-acting insuline
B: activate insulin receptor
C: type 1 and type 2 diabetes
Insulin lispro
103
Irbesartan
A: antihypertensive agent (ARB)
B: block AT-1 angiotensin receptors
C: hypertension, heart failure
104
A: antihypertensive agent (ARB)
B: block AT-1 angiotensin receptors
C: hypertension, heart failure
Irbesartan
105
Isoniazid
A: antimycobacterial drug
B: inhibit synthesis of mycolic acid, an essential component of mycobacterial cell walls, bactericidal against susceptible strains of M tuberculosis
C: first-line treatment against tuberculosis
106
A: antimycobacterial drug
B: inhibit synthesis of mycolic acid, an essential component of mycobacterial cell walls, bactericidal against susceptible strains of M tuberculosis
C: first-line treatment against tuberculosis
Isoniazid
107
Rifampin
A: antimycobacterial drug
B: inhibits DNA- dependent RNA polymerase, thereby blocking production of RNA
C: tuberculosis, atypical mycobacterial infections
108
A: antimycobacterial drug
B: inhibits DNA- dependent RNA polymerase, thereby blocking production of RNA
C: tuberculosis, atypical mycobacterial infections
Rifampin
109
Isotretinoin
A: synthetic retinoid
B: inhibit sebaceous gland size and function
C: severe cystic acne
110
A: synthetic retinoid
B: inhibit sebaceous gland size and function
C: severe cystic acne
Isotretinoin
111
Isosorbide mononitrate
A: nitrate
B: Releases nitric oxide in smooth muscle, whitch activates guanylyl cyclase and increases cGMP, leads to smooth muscle relaxation especially in vessels
C: angina, acute coronary syndrome
112
A: nitrate
B: Releases nitric oxide in smooth muscle, whitch activates guanylyl cyclase and increases cGMP, leads to smooth muscle relaxation especially in vessels
C: angina, acute coronary syndrome
Isosorbide mononitrate
113
Levodopa/benserazide
A: antiparkinsom drug
B: transported into CNS and coverted to dopamine, ameliorates all symptoms of parkinson's disease
C: parkingsons disease
114
A: antiparkinsom drug
B: transported into CNS and coverted to dopamine, ameliorates all symptoms of parkinson's disease
C: parkingsons disease
Levodopa/benserazide
115
Levonorgestrel
A:
116
Mebendazole
A: antihelminthic drug
B: inhibiting microtubule synthesis
C: ascariasis, trichuriasis, hookworm and pinworm infection
117
A: antihelminthic drug
B: inhibiting microtubule synthesis
C: ascariasis, trichuriasis, hookworm and pinworm infection
Mebendazole
118
Memantine
A: cognetive enhancer
B: NMDA receptor channel blocker
C: alzheimer's disease
119
A: cognetive enhancer
B: NMDA receptor channel blocker
C: alzheimer's disease
Memantine
120
Metformin
A: biguanides
B: reduced hepatic and renal gluconeogenesis, decreases endogenous glucose production
C: type 2 diabetes
121
A: biguanides
B: reduced hepatic and renal gluconeogenesis, decreases endogenous glucose production
C: type 2 diabetes
Metformin
122
Methotrexate
A: Disease-modifying antirheumatic drug
B: synthetic antimetabolite, acumulates intracellularly, inhibits AMP deaminase, acumulates AMP, leads to less inflamaton
C: rheumatoid arthritis
123
A: Disease-modifying antirheumatic drug
B: synthetic antimetabolite, acumulates intracellularly, inhibits AMP deaminase, acumulates AMP, leads to less inflamaton
C: rheumatoid arthritis
Methotrexate
124
Metronidazole
A: miscellaneous antimicrobial
B: disruption of electron transport chain, bactericidal against anaerobic bacteria and protozoa
C: C difficile colitis
125
A: miscellaneous antimicrobial
B: disruption of electron transport chain, bactericidal against anaerobic bacteria and protozoa
C: C difficile colitis
Metronidazole
126
Metoprolol
A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension
127
A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension
Metoprolol
| Nebivolol
128
Montelukast
A: Leukotriene antagonist
B: blocks leukotriene D4 receptor, block airway responce to exercise and antigen challenge
C: prophylaxis of asthma
129
A: Leukotriene antagonist
B: blocks leukotriene D4 receptor, block airway responce to exercise and antigen challenge
C: prophylaxis of asthma
Montelukast
130
Methylprednisolone
A: corticosteroid, systemic
B: alters gene expression, reduces mediators of inflammation
C: asthma
131
A: corticosteroid, systemic
B: alters gene expression, reduces mediators of inflammation
C: asthma
Methylprednisolone
132
Morphine
A: strong opioid agonist
B: strong u-receptor agonist, analgesia, relif of anxiety, sedation, slowes gastrointestinal transit
C: severe pain, adjunct in anesthesia, pulmonary edema
133
A: strong opioid agonist
B: strong u-receptor agonist, analgesia, relif of anxiety, sedation, slowes gastrointestinal transit
C: severe pain, adjunct in anesthesia, pulmonary edema
Morphine
134
Nebivolol
A: sympathetic antagonist
B: block Beta1 > Beta2, lower HR and BP
C: hypertension
135
Omeprazole
A: proton pump inhibitor
B: Irreversible blockade of H+/K+ATPase pump in active parietal cells of stomach, long-lasting reduction of stimulated and nocturnal acid secration
C: peptic ulcer disease
136
A: proton pump inhibitor
B: Irreversible blockade of H+/K+ATPase pump in active parietal cells of stomach, long-lasting reduction of stimulated and nocturnal acid secration
C: peptic ulcer disease
Omeprazole
137
Ondansetron
A: antiemetic drug
B: 5-HT3 blockade in gut and CNS, Extremely effective in preventing chemotheraphy induced and postoperative nausea and vomiting
C: postoperative emesis
138
A: antiemetic drug
B: 5-HT3 blockade in gut and CNS, Extremely effective in preventing chemotheraphy induced and postoperative nausea and vomiting
C: postoperative emesis
Ondansetron
139
Oseltamivir
A: antiviral agent
B: neuramidase inhibitor, interfere with the release of progeny influenca virus from infected host cell, halting spread of infection
C: influenza
140
A: antiviral agent
B: neuramidase inhibitor, interfere with the release of progeny influenca virus from infected host cell, halting spread of infection
C: influenza
Oseltamivir
141
Oxytocin
A: pituitary hormone
B: activates oxytocin receptor, increases uterine contractions
C: induction of labor
142
A: pituitary hormone
B: activates oxytocin receptor, increases uterine contractions
C: induction of labor
Oxytocin
143
Pancreatin
A: pancreatic supplement
B: replaces enzymes from animal extracts, improves digestion of diatary fat, protein, and carbohydrates
C: pancreatetomy
144
A: pancreatic supplement
B: replaces enzymes from animal extracts, improves digestion of diatary fat, protein, and carbohydrates
C: pancreatetomy
Pancreatin
145
Paroxetine
A: selective serotonin reuptake inhibitor (SSRI)
B: Highly selective blockade of serotonin transporter (SERT), little effect on norepinephrine transporter (NET)
C: major depression
146
Perindopril
A: angiotensin-coverting enzyme inhibitor
B: inhibit angiotensin converting enzyme, reduces vasoconstriction and aldosteron secretion
C: heart failure
147
A: angiotensin-coverting enzyme inhibitor
B: inhibit angiotensin converting enzyme, reduces vasoconstriction and aldosteron secretion
C: heart failure
Perindopril
148
Permethrin
A: dermatologic application
B: ectoparasiticide
C: scabis
149
A: dermatologic application
B: ectoparasiticide
C: scabis
Permethrin
150
Povidone iodine
A: halogen
B: kill bacteria, fungi and lipid viruses
C: antiseptic
151
A: halogen
B: kill bacteria, fungi and lipid viruses
C: antiseptic
Povidone iodine
152
Procainamide
A: class 1A antiarrhythmic
B: slowes conduction velocity and pacemaker rate
C: atrial arrhytmias
153
A: class 1A antiarrhythmic
B: slowes conduction velocity and pacemaker rate
C: atrial arrhytmias
Procainamide
154
Propranolol
```
A: class 2 antiarrhythmic
B: Beta-adrenoceptor blockade slows AV node automatisity and AV nodal conduction velocity
C: prevention of sudden death
```
155
```
A: class 2 antiarrhythmic
B: Beta-adrenoceptor blockade slows AV node automatisity and AV nodal conduction velocity
C: prevention of sudden death
```
Propranolol
156
Ranitidine
A: H2 blocker
B: blocks H2, reduces nocturnal acid secration
C: acid reflux
157
A: H2 blocker
B: blocks H2, reduces nocturnal acid secration
C: acid reflux
Ranitidine
158
Rivaroxaban
A: anticoagulant
B: direct factor Xa inhibitor
C:prevebtion of venous thrombolism
159
A: anticoagulant
B: direct factor Xa inhibitor
C:prevebtion of venous thrombolism
Rivaroxaban
160
Sildenafil
A: phosphodiesterase inhibitor
B: incrases cGMP, leads to relaxation of smooth muscles
C: erectile dysfunction
161
A: phosphodiesterase inhibitor
B: incrases cGMP, leads to relaxation of smooth muscles
C: erectile dysfunction
Sildenafil
162
Spironolactone
A: potassium-sparing diuretic
B: Pharmacologic antagonist of aldosteron in collecting tubules, Weak antagonism of androgen receptor, reduces Na retension
C: postmyocardial infection
163
A: potassium-sparing diuretic
B: Pharmacologic antagonist of aldosteron in collecting tubules, Weak antagonism of androgen receptor, reduces Na retension
C: postmyocardial infection
Spironolactone
164
Tamsulosin
A: sympathetic antagonists
B: slightly selective for Alpha-1A, blockade of prostaic smooth muscle more the vascular smooth muscle
C: benign prostatic hyperplasia
165
A: sympathetic antagonists
B: slightly selective for Alpha-1A, blockade of prostaic smooth muscle more the vascular smooth muscle
C: benign prostatic hyperplasia
Tamsulosin
166
Terbinafine
A: antifungal
B: inhibits epoxidation of squalene in fungi, increased levels are toxic to them, reduces ergosterol
C: mucocutaneoys fungsl infection
167
A: antifungal
B: inhibits epoxidation of squalene in fungi, increased levels are toxic to them, reduces ergosterol
C: mucocutaneoys fungsl infection
Terbinafine
168
Tolterodine
A: antimuscarinic agent
B: M-3 selective block
C: urinary incontinence
169
A: antimuscarinic agent
B: M-3 selective block
C: urinary incontinence
Tolterodine
170
Torasemide
A: loop diuretic
B:Inhibition of the Na/K/2Cl in the ascending limb of Henle's loop, marked increase in NaCl excretion
C: pulmonary edema, hypertension, etc
171
Trihexyphenidyl
A: antimuscarinic agent
B: antagonist at M receptors in basal ganglia, reduces tremor and rgidity
C: parkingson's disease
172
A: antimuscarinic agent
B: antagonist at M receptors in basal ganglia, reduces tremor and rgidity
C: parkingson's disease
Trihexyphenidyl
173
Tropicamide
A: anticholinergic drug
B: competative antagonism at all muscarinic receptors
C: in ophthalmology to cause mydriasis and cycloplegia, and as antidote for severe cholinesterase inhibitor poisoning
174
Valproate acid
A: antiseizure drug
B: blocks high-frequency firing of neuron, modifies amino acid metabolism
C: myoclonic seizures
175
A: antiseizure drug
B: blocks high-frequency firing of neuron, modifies amino acid metabolism
C: myoclonic seizures
Valproate acid
176
Warfarin
A: anticoagulant
B: cause blockad of y-carboxylation of several endogenous produced coagulation factors, making the biological inactive
C: DVT profylaxis
177
A: anticoagulant
B: cause blockad of y-carboxylation of several endogenous produced coagulation factors, making the biological inactive
C: DVT profylaxis
Warfarin
178
Zolmitriptan
A: anti migrane drug (triptan)
B: 5-HT(1D/1B) agonist
C: migrane
179
A: anti migrane drug (triptan)
B: 5-HT(1D/1B) agonist
C: migrane
Zolmitriptan
180
Zolpidem
A: newer hypnotic
B: bind selectivly to a subunit og GABA(A) acting like benzodiasapines, rapid onset of hypnosis
C: sleep disorders
181
A: newer hypnotic
B: bind selectivly to a subunit og GABA(A) acting like benzodiasapines, rapid onset of hypnosis
C: sleep disorders
Zolpidem
182
Salbutamol
A: selective Beta2 agonist
B: prompt, efficacious broncodialation
C: acute asthmatic broncospasm
183
A: selective Beta2 agonist
B: prompt, efficacious broncodialation
C: acute asthmatic broncospasm
Salbutamol
184
Physostigmine
A: intermediate-acting cholinesterase inhibitor
B: blocks AChE
C: myastavia gravis
185
A: intermediate-acting cholinesterase inhibitor
B: blocks AChE
C: myastavia gravis
Physostigmine
186
Ursodeoxycholic acid
A: bile acid theraphy drug
B: reduces cholesterol secration into bile, dissolve gallstones,
C: gallstone
187
A: bile acid theraphy drug
B: reduces cholesterol secration into bile, dissolve gallstones,
C: gallstone
Ursodeoxycholic acid
188
Loratadine
A: second-generation H1 blocker
B: blocks H1 receptors, prevents releace of histamine
C: hey fever
189
A: second-generation H1 blocker
B: blocks H1 receptors, prevents releace of histamine
C: hey fever
Loratadine
190
Etoricoxib
A: NSAID
B: cox-2 selective inhibitor
C: block peripheral inflamation
191
A: NSAID
B: cox-2 selective inhibitor
C: block peripheral inflamation
Etoricoxib
192
Ephedrine
A: agonist of alpha and beta
B: same as A
C: not used
193
A: agonist of alpha and beta
B: same as A
C: not used
Ephedrine
194
Levonorgestrel
A: synthetic progrestin
B: inhibit ovulation
C: morning after pil
195
A: synthetic progrestin
B: inhibit ovulation
C: morning after pil
Levonorgestrel
196
Mesalazine
A: antiinflamatory
B: inhibit eicosanoid inflamatory mediators
C: inflamatory bowel disease
197
A: antiinflamatory
B: inhibit eicosanoid inflamatory mediators
C: inflamatory bowel disease
Mesalazine
198
Piracetam
A: nootropic
B: increases cognitive function
C: dementia
199
A: nootropic
B: increases cognitive function
C: dementia
Piracetam
200
Adrenalin
A: catochlomamine
B: adrengenic agonist
C: hypotension
201
A: catochlomamine
B: adrengenic agonist
C: hypotension
Adrenalin
202
Acetylsalcylic acid
A: NSAID
B: cox inhibition
C: prevention of heart attack
203
A: NSAID
B: cox inhibition
C: prevention of heart attack
Acetylsalcylic acid
204
Amiodarone
```
A: class 3 antiarrhytmic
B: bloks I(kr), I(Na), I(Ca-L), prolongs action potential an QT interval
C: serious ventricular arrhytmias
```
205
```
A: class 3 antiarrhytmic
B: bloks I(kr), I(Na), I(Ca-L), prolongs action potential an QT interval
C: serious ventricular arrhytmias
```
Amiodarone
206
Co-triamaxazole
A: folate antagonist
B: Synergistic combination of folate antagonists blocks purine production and nucleic acid synthesis, bactericidal activity against susceptible bacteria
C: UTI
207
A: folate antagonist
B: Synergistic combination of folate antagonists blocks purine production and nucleic acid synthesis, bactericidal activity against susceptible bacteria
C: UTI
Co-triamaxazole
