Drugs Used In Disorders Of Coagulation

Question 0

Unfractionated heparin (UFH)

Answer 0

Indirect thrombin inhibitor

Question 1

Indirect thrombin inhibitors

Answer 1

Unfractionated heparin (UFH)
Low-molecular-weight heparin (LMWH)
Fondaparinux

Question 2

Low-molecular-weight heparin (LMWH)

Answer 2

Indirect thrombin inhibitor

Question 3

Fondaparinux

Answer 3

Indirect thrombin inhibitor

Question 4

Antithrombin lll

Answer 4

Endogenous anticoagulant

Question 5

Antithrombin lll

Actions

Answer 5

Antithrombin inhibits clotting factor proteases, especially thrombin (lla), lXa, and Xa, by forming equimolar stable complexes with them. In the absence of heparin, these reactions are slow; in presence of heparin, they are accelerated 1000-fold.

Question 6

inhibits clotting factor proteases, especially thrombin (lla), lXa, and Xa, by forming equimolar stable complexes with them. In the absence of heparin, these reactions are slow; in presence of heparin, they are accelerated 1000-fold.

Answer 6

Antithrombin lll

Actions

Question 7

LMW heparins

Answer 7

Enoxaparin
Dalteparin
Tinzaparin

Question 8

Enoxaparin

Answer 8

LMW heparin

Question 9

Dalteparin

Answer 9

LMW heparin

Question 10

Tinzaparin

Answer 10

LMW heparin

Question 11

Protamine sulfate

Usage

Answer 11

Antagonist of heparin

Question 12

Antagonist of heparin

Answer 12

Protamine sulfate

Usage

Question 13

Oral direct factor Xa inhibitors

Answer 13

Rivaroxaban

Apixaban

Question 14

Apixaban

Answer 14

Oral direct factor Xa inhibitor

Question 15

Rivaroxaban

Answer 15

Oral direct factor Xa inhibitor

Question 16

Rivaroxaban
Apixaban

Actions

Answer 16

Inhibit factor Xa, in the final common pathway of clotting

Question 17

Inhibit factor Xa, in the final common pathway of clotting

Answer 17

Rivaroxaban
Apixaban

Actions

Question 18

Direct thrombin inhibitors (DTIs)

Answer 18

Hirudin
Bivalirudin
Argatroban
Melagatran
Dabigatran etexilate mesylate

Question 19

Parenteral direct thrombin inhibitors (DTIs)

Answer 19

Hirudin
Lepirudin
Bivalirudin
Argatronan

Question 20

Hirudin

Answer 20

Parenteral direct thrombin inhibitor (DTI)

Question 21

Lepirudin

Answer 21

Parenteral direct thrombin inhibitor (DTI)

Question 22

Bivalirudin

Answer 22

Parenteral direct thrombin inhibitor (DTI)

Question 23

Argatronan

Answer 23

Parenteral direct thrombin inhibitor (DTI)

Question 24

Oral direct thrombin inhibitor (DTI

Answer 24

Dabigatran etexilate mesylate

Question 25

Dabigatran etexilate mesylate

Answer 25

Oral direct thrombin inhibitor (DTI

Question 26

Fibrinolytic drugs

Answer 26

``` Streptokinase Urokinase Alteplase Reteplase Tenecteplace ```

Question 27

Streptokinase

Answer 27

Fibrinolytic drug

Question 28

Urokinase

Answer 28

Fibrinolytic drug

Question 29

Alteplase

Answer 29

Fibrinolytic drug (Manufactured human t-PA)

Question 30

Tenecteplace

Answer 30

Fibrinolytic drug (Manufactured human t-PA)

Question 31

Reteplase

Answer 31

Fibrinolytic drug (Manufactured human t-PA)

Question 32

Manufactured human t-PA

Answer 32

Alteplase Reteplase Tenecteplace

Question 33

Fibrolytic drugs Indications

Answer 33

Pulmonary embolism with hemodynamic instability Severe deep venous thrombus Ascending thrombophlebitis (Acute myocardial infarction, depends on circumstances)

Question 34

Pulmonary embolism with hemodynamic instability Severe deep venous thrombus Ascending thrombophlebitis (Acute myocardial infarction, depends on circumstances)

Answer 34

Fibrolytic drugs Indications

Question 35

Antiplatelet agents

Answer 35

``` Aspirin Ticlopidine Clopidogrel Prasugrel Abciximab Eptifibatide Tirofiban Dipyridamole Cilostazol ```

Question 36

Aspirin

Answer 36

Antiplatelet agent (cyclooxygenase inhibitor)

Question 37

Ticlopidine

Answer 37

Antiplatelet agent (ADP pathway inhibitor)

Question 38

Clopidogrel

Answer 38

Antiplatelet agent (ADP pathway inhibitor)

Question 39

Prasugrel

Answer 39

Antiplatelet agent (ADP pathway inhibitor)

Question 40

Abciximab

Answer 40

Antiplatelet agent (glycoprotein llb/llla inhibitor)

Question 41

Eptifibatide

Answer 41

Antiplatelet agent (glycoprotein llb/llla inhibitor)

Question 42

Tirofiban

Answer 42

Antiplatelet agent (glycoprotein llb/llla inhibitor)

Question 43

Antiplatelet agents (glycoprotein llb/llla inhibitors)

Answer 43

Abciximab Eptifibatide Tirofiban

Question 44

Antiplatelet agents (ADP pathway inhibitors)

Answer 44

Ticlopidine Clopidogrel Prasugrel

Question 45

Aminocaproic acid

Answer 45

Clinically useful inhibitor of fibrinolysis

Question 46

Clinically useful inhibitor of fibrinolysis

Answer 46

Aminocaproic acid