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Pharma > Random Urinary Drug > Flashcards

Random Urinary Drug Flashcards

0
Q

Tamsulosin

A

Alpha-adrenoceptor antagonist

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1
Q

Alpha-adrenoceptor antagonist

A

Tamsulosin

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2
Q

Tamsulosin

Mechanism of action

A

Tamosulosin is slightly selective for Alpha-1A

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3
Q

Slightly selective for Alpha-1A

A

Tamsulosin

Mechanism of action

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4
Q

Tamsulosin

Effects

A

Alpha-1A blockade may relax prostatic smooth muscles more than vascular smooth muscle

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5
Q

Alpha-1A blockade may relax prostatic smooth muscles more than vascular smooth muscle

A

Tamsulosin

Effects

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6
Q

Tamsulosin

Clinical applications

A

Benign prostatic hyperplasia

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7
Q

Benign prostatic hyperplasia

A

Tamsulosin

Clinical applications

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8
Q

Tamsulosin

Toxicity

A

Orthostatic hypotension may be less common with this subtype

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9
Q

Orthostatic hypotension may be less common with this subtype

A

Tamsulosin

Toxicity

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10
Q

5a- reductase inhibitors

A

Finasteride

Dustasteride

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11
Q

Finasteride

A

5a- reductase inhibitor

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12
Q

Dustasteride

A

5a- reductase inhibitor

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13
Q

Finasteride

Mechanism of action

A

Blocks conversion of dihydrotestosteron

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14
Q

Blocks conversion of dihydrotestosteron

A

Finasteride

Mechanism of action

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15
Q

Finasteride

Clinical application

A

Benign prostatic hyperplasia

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16
Q

Allopurinol

A

Xanthine oxidase inhibitor

17
Q

Xanthine oxidase inhibitor

A

Allopurinol

18
Q

Allopurinol

Indications

A

First-line agent for the treatment of chronic gout

19
Q

First-line agent for the treatment of chronic gout

A

Allopurinol

20
Q

Desmopressin

A

Long-acting synthetic analog of vasopressin with minimal pressor activity and an antidiuretic-to-pressor ratio 4000 times that of vasopressin

21
Q

Long-acting synthetic analog of vasopressin with minimal pressor activity and an antidiuretic-to-pressor ratio 4000 times that of vasopressin

A

Desmopressin

22
Q

Desmopressin

Clinical applications

A

Pituitary diabetes insipidus
Pediatric primary nocturnal enuresis
Hemophilia A and von Willebrand disease

23
Q

Pituitary diabetes insipidus
Pediatric primary nocturnal enuresis
Hemophilia A and von Willebrand disease

A

Desmopressin

Clinical applications

24
Q

Desmopressin

Vasopressin

A

Vasopressin receptor agonists

25
Q

Vasopressin receptor agonists

A

Desmopressin

Vasopressin

26
Q

Desmopressin

A

Vasopressin receptor agonist

27
Q

Desmopressin

Mechanism of action

A

Relatively selective vasopressin V2 receptor agonist

28
Q

Relatively selective vasopressin V2 receptor agonist

A

Desmopressin

Mechanism of action

29
Q

Desmopressin

Effects

A

Acts in the kidney colecting duct cells to decrease the excretion of water

Acts on extra renal V2 receptors to increase factor ( V||| ) and von Willbrand factor

30
Q

Acts in the kidney colecting duct cells to decrease the excretion of water

Acts on extra renal V2 receptors to increase factor ( V||| ) and von Willbrand factor

A

Desmopressin

Effects

31
Q

Desmopressin

Toxicity

A

Gastrointestinal disturbances
Headache
Hyponatremia
Allergic reactions

32
Q

Phosphodiesterase isoform 5 (PDE-5) inhibitors

A

Sildenafil (Viagra)
Tadalafil
Vardenafil

33
Q

Sildenafil (Viagra)

A

Phosphodiesterase isoform 5 (PDE-5) inhibitor

34
Q

Tadalafil

A

Phosphodiesterase isoform 5 (PDE-5) inhibitor

35
Q

Vardenafil

A

Phosphodiesterase isoform 5 (PDE-5) inhibitor

36
Q

Phosphodiesterase isoform 5 (PDE-5) inhibitor

Clinical applications

A

Erectile dysfunction

Possible use: pulmonary arterial hypertension
cystic fibrosis
( BPH )

37
Q

Alprostadil

A

PGE1 anolog

38
Q

PGE1 anolog

A

Alprostadil

39
Q

Alprostadil

Clinical application

A

Erectile dysfunction

Pharma (29 decks)

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