Test 3 Review Flashcards
Which of the following is not a function of blood?
a. Transport immune cells
b. Regulate body temperature
c. Protects against disease
d. Produce white blood cells
d. Produce white blood cells
What are 3 functions of blood?
- Transports gases, nutrients and wastes, hormones, immune cells, clotting factors etc.
- Regulate many things such as pH, body temperature, and water content.
- Protection via white blood cells and also via clotting.
Does blood produce red and white blood cells?
No
Where are red and white blood cells produced?
Red bone marrow
You go to the mountains for a 2 week vacation. During this time your body needs to acclimate to the lower oxygen content. Which of the following will happen?
a. EPO will stimulate the red blood cells to divide and proliferate.
b. Your kidneys will begin to produce erythropoietin (EPO).
c. Thrombompoeitin (TPO) will be produced by the liver.
d. The viscosity of your blood will decrease.
b. Your kidneys will begin to produce erythropoietin (EPO).
What is produced by the kidney to stimulate RBC production?
Erythropoietin
What is produced by the liver to stimulate platelet formation?
Thrombopoietin
What term means how thick or thin blood is?
Viscosity
What can change viscosity?
A change in plasma/plasma proteins or hematocrit.
Increased viscosity which will result in increased resistance and decreased flow can come from?
Increased hematocrit
Amount of dissolved solutes in blood.
Osmolarity
How can osmolarity alter blood pressure?
Water will follow increased ion concentration (increased NaCl =
increased BP)
You go to the doctor to have a routine blood test. They collect your
blood and centrifuge it. Which of the following is accurate?
a. The top layer will be the plasma layer and it makes up 45% of the
total blood
b. The erythrocytes, platelets, leukocytes and plasma proteins make
up the formed elements of the blood
c. The bottom layer is the hematocrit. It contains all of the formed elements
d. In the middle there is a thin layer called the buffy coat made up of
the white blood cells and platelets
d. In the middle there is a thin layer called the buffy coat made up of
the white blood cells and platelets
Plasma is ___% of whole blood
55%
Plasma is ___% water?
92%
Proteins make up __% Plasma?
7%
What proteins make up plasma and at what percentage?
Albumin 58%
Globulins 37%
Fibrinogen 4%
Regulator Proteins <1%
What solutes make up 1% of plasma?
Electrolytes
Nutrients
Respiratory Gasses
Waste Products
What makes up less than 1% of whole blood?
Buffy Coat
What platelets make up the buffy coat and at what percentages.
Neutrophils 50 - 70% Lymphocytes 20 - 40% Leukocytes 4.5 - 11% Monocytes 2 - 8% Eosinophils 1 - 4% Basophils 0.5 - 1%
What makes up 44% of whole blood?
Erythrocytes
What three parts make up a blood sample?
- Plasma - 55%
- Buffy Coat - <1%
- Erythrocytes - 44%
Which of the following plasma proteins functions to attack viruses and bacteria (antibodies) a. Albumin b. Globulins c. Fibrinogen d. Lymphocytes
b. Globulins
What is the most abundant of the plasma proteins?
Albumin
Which plasma protein?
• Functions as a carrier for fatty acids and certain hormones
• Majorly contributes to osmotic pressure (pressure that keeps water in
the bloodstream)
• Regulate blood pressure, blood flow and fluid balance
Albumin
Which plasma protein?
• Carrier proteins for lipids, iron and fat-soluble vitamins
• Gamma globulins function to attack viruses and bacteria (antibodies)
Globulins
Which plasma protein plays an essential role in blood clot formation?
Fibrinogen
Which of the following is TRUE of an erythrocyte?
a. They have a biconcave disc like structures
b. They carry only oxygen
c. They use oxygen to provide energy so they can carry oxygen to
other tissues
d. They have a nucleus but lack other organelles
a. They have a biconcave disc like structure
What are 4 characteristics of red blood cells?
- Carry gasses
- Biconcave disc shape
- Lack a nucleus and organelles (do not live long)
- Use anaerobic respiration (don’t use oxygen they carry)
- Greatly contribute to viscosity.
More red blood cells does what to viscosity?
Increased viscosity
Which of the following is FALSE of hemoglobin?
a. Hemoglobin is composed of 4 globin chains 4 heme molecules
b. Each iron molecule binds 4 oxygen molecules
c. In the tissues oxygen detaches from the hemoglobin causing it to
return to its normal shape and become dark red. This would be
referred to as deoxyhemoglobin
d. In the lungs oxygen diffuses from the alveoli of the lungs, enters the
capillaries and binds to the iron of the hemoglobin causing the
hemoglobin to turn bright red and be called oxyhemoglobin
b. Each iron molecule binds 4 oxygen molecules
What is the oxygen carrying
component of the RBC’s?
Hemoglobin
What is hemoglobin composed of?
• 4 Globin chains that bind the ring-like heme group • 4 Heme molecules. Each has an iron in the center. • Each iron can bind one oxygen so each heme can bind 1 oxygen and each hemoglobin can bind 4 oxygens.
A red pigment that becomes bright red when oxygen is bound to the iron molecule.
Heme
During oxygen loading in the lungs oxygen diffuses from the alveoli
into the capillaries where it binds to the iron of the hemoglobin. This
is __________ and will have a red color.
oxyhemoglobin
In the tissues, the process is reversed, oxygen detaches from the
hemoglobin causing it to return to its normal shape and become dark
red. This is called?
Deoxyhemoglobin
Which of the following is FALSE?
a. Precursor (blast) cells can differentiate into any of the formed
elements
b. The lymphoid line gives rise to T-lymphocytes
c. Megakaryocytes break off pieces to form platelets
d. Basophils, neutrophils and eosinophils are all granulocytes
a. Precursor (blast) cells can differentiate into any of the formed
elements
Hemopoiesis starts from a what?
Hemocytoblast
Your patient needs a blood transfusion. They have A- blood. Which of the following could donate blood. a. His sister with type A+ blood b. His friend who has O- blood c. His brother that has AB- blood d. His husband with type B- blood
b. His friend who has O- blood
Which of the following would most likely represent a viral infection?
a. An increase in neutrophils
b. An increase in neutrophils and eosinophils
c. An increase in lymphocytes and monocytes
d. An increase in basophils and macrophages
c. An increase in lymphocytes and monocytes
What cells ↑ during bacterial and fungal infections, burns, stress and inflammation?
Neutrophils
What cells ↑ during parasitic infections and allergies?
Eosinophils
What cells ↑ in response to allergies, leukemias, cancers?
Basophils
What cells ↑ in viral infections, bacterial infections, cancers?
Lymphocytes
What cells ↑ in viral infections and inflammation?
Monocytes and Macrophages
What cell carries out phagocytosis of entire pathogen?
Neutrophils
What cells carry out phagocytosis of allergens and releases enzymes that destroy parasites/worm?
Eosinophils
What cells secrete histamine and heparin?
Basophils
What does histamine do when secreted?
Increases blood flow
What does heparin do when secreted?
Anti-coagulant promotes mobility of WBCs
What type of cells destroy cancer and viruses and secrete antibodies and provide immune memory?
Lymphocytes
What do monocytes differentiate into when they leave the blood and enter tissue?
Macrophages
Which of the following is TRUE?
a. The heart is located in the mediastinum spanning from the 2nd to
the 5th intercostal space
b. The serous pericardium helps to anchor the heart in the mediastinum
c. The apex is the pointed end formed by the tip of the right ventricle
d. The base is posterior surface formed mostly by the posterior parts of the atria
a. The heart is located in the mediastinum spanning from the 2nd to
the 5th intercostal space
The heart is located in the _________ spanning from the ___ to the
___ intercostal space
mediastinurm, 2nd, 5th
What surrounds the heart?
Pericardium
What makes up the pericardium?
Fibrous Pericardium
Serous Pericardium
What two layers make up serous pericardium?
Parietal Pericardium
Visceral Pericardium
What is between parietal pericardium and visceral pericardium?
A fluid layer in between that helps reduce friction during movement.
What protects the heart and anchors it in the mediastinum?
Fibrous Pericardium
Going from superficial to deep what are the layers of the heart wall.
a. Endocardium, myocardium, epicardium
b. Myocardium, epicardium, endocardium
c. Epicardium, myocardium, endocardium
d. Endocardium, epicardium, myocardium
c. Epicardium, myocardium, endocardium
Which of the following is FALSE?
a. The right atrium receives blood from the systemic circulation and
contains oxygenated blood
b. The left atrium receives blood from the pulmonary circulation and
contains oxygenated blood
c. The left ventricle receives blood from the left atria and contains
oxygenated blood
d. The right ventricle receives blood from the right atria and contains
deoxygenated blood
a. The right atrium receives blood from the systemic circulation and contains oxygenated blood
Which of the following structures is a remnant structure from the embryo where it was used to shunt blood from the right to left atrium
a. Fossa ovalis
b. Foramen ovale
c. Ligamentum arteriosum
d. Ductus arteriosis
a. Fossa ovalis
This shunts blood from right to left atrium in embryo thus bypassing the pulmonary circulation.
Foramen Ovale
The ______ _________ is a group of small vessels found in the embryo to
shunt blood from the pulmonary artery into the aorta thereby bypassing
the non-functioning fetal lungs
Ductus arteriosus
What is the remnant structure of the Ductus Arteriosus?
Ligamentum Arteriosum
Where is ligamentum arteriosum located?
Between aorta and pulmonary artery
Which of the following is TRUE?
a. The right ventricle pumps blood into the pulmonary trunk
b. The left atria receives oxygenated blood from the pulmonary arteries
c. The right atria contains a type of muscle called trabeculae carnae
d. The bicuspid valve is found between the right atria and right ventricle
a. The right ventricle pumps blood into the pulmonary trunk
Which of the following is FALSE?
a. Semilunar valves are open during ventricular relaxation
b. Semilunar valves are closed during atrial contraction
c. Atrioventricular valves are open during atrial contraction
d. Atrioventricular valves are closed during ventricular contraction
a. Semilunar valves are open during ventricular relaxation
Where is pulmonary semilunar valve found?
Between right ventricle and pulmonary trunk
Where is aortic semilunar valve found?
Between left ventricle and aorta.
When ventricles contract, what happens to semilunar valves?
The valves open
When the ventricles rest, what happens to the semilunar valves?
The valves close
Where is the tricuspid valve located?
Between right atrium and right ventricle.
Where is the bicuspid valve located?
Between left atrium and left ventricle
AV valves are attached to fibers called?
Chordae Tendineae
What muscles do the chordae tendineae attach to?
Papillary Muscles
What happens to atrioventricular valves when the ventricles are relaxed?
The valves open
What happens to atrioventricular valves when the ventricles contract?
The valves close
Which of the following is not a function of the fibrous skeleton of the heart?
a. Serves as attachment points for the valves
b. Prevents overstretch of the valves
c. Prevents direct spread of electrical impulses from the atria to the
ventricles
d. Propagates electrical potentials from the SA node to the AV node
d. Propagates electrical potentials from the SA node to the AV node
Which of the following is false of the coronary circulation?
a. The right and left coronary arteries come directly off the aorta
b. The cardiac veins empty deoxygenated blood into the coronary
sinus
c. The coronary sinus empties into the left atria
d. The anterior interventricular artery branches off of the left coronary
artery
c. The coronary sinus empties into the left atria
Which of the following is the correct order for the cardiac conduction
system?
a. SA node, AV node, AV bundle, bundle branches, purkinje fibers
b. AV node, SA node, AV bundle, bundle branches, purkinje fibers
c. SA node, AV node, AV bundle, purkinje fibers, bundle branches,
d. AV node, AV bundle, SA node, bundle branches, purkinje fibers
a. SA node, AV node, AV bundle, bundle branches, purkinje fibers
The SA node acts as the natural pacemaker of the heart and has a rhythm of round 90-100 beats yet the normal heart rate is only 65-80 beats/minute.
Why is this?
a. The sympathetic neurons slow down the heart rate via the vagus nerve
b. The parasympathetic neurons slow down the heart rate via the vagus
nerve
c. The sympathetic neurons slow down the heart rate via the sympathetic
chain
d. The parasympathetic neurons slow down the heart rate via the
sympathetic chain
b. The parasympathetic neurons slow down the heart rate via the vagus
nerve
Chemicals that change the heart rate are known as
a. Chronotropic chemicals
b. Stimulants
c. Depressants
d. Cardioirritants
a. Chronotropic chemicals
Which of the following is NOT TRUE of the veins?
a. Veins have thinner walls than compared to arteries
b. Veins have smaller lumens than arteries
c. The blood pressure in veins is lower than in arteries
d. Veins do not help to regulate blood pressure and flow
b. Veins have smaller lumens than arteries
Where do arteries transport blood?
AWAY from the heart veins
Where do veins transport blood?
TOWARDS the heart
What type of blood do arteries usually transport?
Oxygenated blood
What type of blood do veins carry?
Deoxygenated blood
Do arteries have thicker or thinner walls?
Thicker
Do veins have thicker or thinner walls?
Thinner
Do arteries have smaller or larger lumens?
Smaller lumens