Test 3 hematology Flashcards

1
Q

blood cell production

A

hematopoiesis

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2
Q

development of red blood cells

A

erythropoiesis

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3
Q

hormone secreted by the kidney that helps the process of erythropoiesis

A

erythropoietin

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4
Q

has mitochondria and ribosome and capable of producing hem

Do not carry as much oxygen

A

reticulocyte

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5
Q

what happens to Hgb during RBC lysis

A

goes back into circulation

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6
Q

what happens to globulin during RBC lysis

A

reused for amino acid

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7
Q

what happens to iron during RBC lysis

A

goes to liver/spleen for reuse

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8
Q

what happens to bilirubin during RBC lysis

A

goes to liver to be conjugated and then to urine and stool for excretion

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9
Q

control of bleeding

A

hemostasis

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10
Q

make platelets sticky

A

ADP

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11
Q

produced by platelets and attracts more platelets to site

A

Thromboxane A

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12
Q

adds stability to plug

A

fibrinogen

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13
Q

attach to proteins

A

von williebrand factors

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14
Q

undamaged neighbor cells releases what for vasodilation

A

Prostaglandin PGI2

Nitric oxide

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15
Q

formed as plug traps circulating RBCs and macrophages

Stabilized by fibrinogen

A

Blood clot

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16
Q

the inactive precursor of plasmin

Produced in the liver

A

Plasminogen

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17
Q

is a seine protease that degrades fibrin polymers in clots

A

plasmin

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18
Q

decrease number of circulating RBCs and or abnormal Hgb

A

anemia

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19
Q

normcytic and normchromic anemias

A

Hemolytic
posthemorrhagic
anemia of chronic disease

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20
Q

macrocytic and normochromic

A

pernicious anemia

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21
Q

microcytic and hypochromic

A

iron deficiency

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22
Q

congenital or autoimmune deficiency of intrinsic factor that impaired absorption of vitamin B12
Increases abnormal RBC production

A

pernicious anemia

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23
Q

depleted iron stores

24
Q

decrease transport to bone marrow causing iron-deficient erythopoiesis

25
begins when the small hemoglobin-deficent cells enter the circulation to replace normal aged erythrocytes that have been romped form the circulation
stage 3
26
caused by acute blood loss
posthemorragic anemia
27
is premature accelerated destruction of erythrocytes, wither episodically or continuously
hemolytic anemias
28
is a mild to moderate anemia resulting from decreased erythropoiesis in individuals with conditions of chronic systemic diseases or inflammation
anemia of chronic disease
29
enlarged spleen
splenomegaly
30
enlarged liver
hepatomegaly
31
excessive red blood cell production
polycythemia
32
is a physiological response resulting from increase erythropoietin secretion in response to chronic hypoxia
secondary polycythemia
33
results from abnormal regulation of multi potent hematopoietic stem cells
polycythemia vera (primary) polycythemia
34
treatment for polycythemia
phelbotomy Low dose ASA hydroxyurea
35
increased WBC
leukocytosis
36
decrease in WBC
leukopenia
37
left shift
increased immature neutrophils
38
too few platelets
thrombocytopenia
39
WNL number of platelets
140,000-340,000
40
platelet count for thrombocytopenia
less than 100,000
41
platelet count for spontaneous bleeding
less than 20,000
42
small, sq bleeding
petechiae
43
large, sq bleeds
purpura
44
bruising or contusion | Hemorrhage in mucous membrane or skin
ecchymosis
45
nodular enlargement
lymphadenopathy
46
cancer of one WBC type in the bone marrow
leukemia
47
is characterized by undifferentiated or immature cells, and the onset of the disease is abrupt and rapid
acute leukemia
48
the predominant cell is more differentiated but does not function normally, with a relatively slow progression
chronic leukemia
49
involves immature lymphocytes
lymphocytic
50
involves pluripotent myeloid stem cells
myelocytic
51
cancer of single group of lymphoid tissue Clonal disorder of B cell, T cell, or monocyte Reed-Sternberg cells
hodgkin lymphoma
52
what will you see in a lymph node biopsies with someone who has hodgkin lymphoma
reed-sternberg cells
53
Diffuse cancer of lymph tissue | Primarily B cell lymphocyte
Non-hodgkin lymphoma
54
Clonal disorder with proliferation of B lymphocyte and plasma cells Disperse throughout the circulation and deposit and bones causing bone pain
Multiple myeloma
55
congenital coagulation and platelet disorder
hemophilias
56
plasma clotting factor deficiency deals with which factors
VIII IX XI
57
ia an acquired clinical syndrome characterized by widespread activation of coagulation, resulting in the formation of fibrin clots in medium and small vessels throughout the body
Disseminated intravascular coagulation DIC