Test 3 hematology Flashcards

1
Q

blood cell production

A

hematopoiesis

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2
Q

development of red blood cells

A

erythropoiesis

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3
Q

hormone secreted by the kidney that helps the process of erythropoiesis

A

erythropoietin

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4
Q

has mitochondria and ribosome and capable of producing hem

Do not carry as much oxygen

A

reticulocyte

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5
Q

what happens to Hgb during RBC lysis

A

goes back into circulation

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6
Q

what happens to globulin during RBC lysis

A

reused for amino acid

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7
Q

what happens to iron during RBC lysis

A

goes to liver/spleen for reuse

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8
Q

what happens to bilirubin during RBC lysis

A

goes to liver to be conjugated and then to urine and stool for excretion

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9
Q

control of bleeding

A

hemostasis

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10
Q

make platelets sticky

A

ADP

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11
Q

produced by platelets and attracts more platelets to site

A

Thromboxane A

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12
Q

adds stability to plug

A

fibrinogen

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13
Q

attach to proteins

A

von williebrand factors

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14
Q

undamaged neighbor cells releases what for vasodilation

A

Prostaglandin PGI2

Nitric oxide

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15
Q

formed as plug traps circulating RBCs and macrophages

Stabilized by fibrinogen

A

Blood clot

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16
Q

the inactive precursor of plasmin

Produced in the liver

A

Plasminogen

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17
Q

is a seine protease that degrades fibrin polymers in clots

A

plasmin

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18
Q

decrease number of circulating RBCs and or abnormal Hgb

A

anemia

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19
Q

normcytic and normchromic anemias

A

Hemolytic
posthemorrhagic
anemia of chronic disease

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20
Q

macrocytic and normochromic

A

pernicious anemia

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21
Q

microcytic and hypochromic

A

iron deficiency

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22
Q

congenital or autoimmune deficiency of intrinsic factor that impaired absorption of vitamin B12
Increases abnormal RBC production

A

pernicious anemia

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23
Q

depleted iron stores

A

stage I

24
Q

decrease transport to bone marrow causing iron-deficient erythopoiesis

A

stage II

25
Q

begins when the small hemoglobin-deficent cells enter the circulation to replace normal aged erythrocytes that have been romped form the circulation

A

stage 3

26
Q

caused by acute blood loss

A

posthemorragic anemia

27
Q

is premature accelerated destruction of erythrocytes, wither episodically or continuously

A

hemolytic anemias

28
Q

is a mild to moderate anemia resulting from decreased erythropoiesis in individuals with conditions of chronic systemic diseases or inflammation

A

anemia of chronic disease

29
Q

enlarged spleen

A

splenomegaly

30
Q

enlarged liver

A

hepatomegaly

31
Q

excessive red blood cell production

A

polycythemia

32
Q

is a physiological response resulting from increase erythropoietin secretion in response to chronic hypoxia

A

secondary polycythemia

33
Q

results from abnormal regulation of multi potent hematopoietic stem cells

A

polycythemia vera (primary) polycythemia

34
Q

treatment for polycythemia

A

phelbotomy
Low dose ASA
hydroxyurea

35
Q

increased WBC

A

leukocytosis

36
Q

decrease in WBC

A

leukopenia

37
Q

left shift

A

increased immature neutrophils

38
Q

too few platelets

A

thrombocytopenia

39
Q

WNL number of platelets

A

140,000-340,000

40
Q

platelet count for thrombocytopenia

A

less than 100,000

41
Q

platelet count for spontaneous bleeding

A

less than 20,000

42
Q

small, sq bleeding

A

petechiae

43
Q

large, sq bleeds

A

purpura

44
Q

bruising or contusion

Hemorrhage in mucous membrane or skin

A

ecchymosis

45
Q

nodular enlargement

A

lymphadenopathy

46
Q

cancer of one WBC type in the bone marrow

A

leukemia

47
Q

is characterized by undifferentiated or immature cells, and the onset of the disease is abrupt and rapid

A

acute leukemia

48
Q

the predominant cell is more differentiated but does not function normally, with a relatively slow progression

A

chronic leukemia

49
Q

involves immature lymphocytes

A

lymphocytic

50
Q

involves pluripotent myeloid stem cells

A

myelocytic

51
Q

cancer of single group of lymphoid tissue
Clonal disorder of B cell, T cell, or monocyte
Reed-Sternberg cells

A

hodgkin lymphoma

52
Q

what will you see in a lymph node biopsies with someone who has hodgkin lymphoma

A

reed-sternberg cells

53
Q

Diffuse cancer of lymph tissue

Primarily B cell lymphocyte

A

Non-hodgkin lymphoma

54
Q

Clonal disorder with proliferation of B lymphocyte and plasma cells
Disperse throughout the circulation and deposit and bones causing bone pain

A

Multiple myeloma

55
Q

congenital coagulation and platelet disorder

A

hemophilias

56
Q

plasma clotting factor deficiency deals with which factors

A

VIII
IX
XI

57
Q

ia an acquired clinical syndrome characterized by widespread activation of coagulation, resulting in the formation of fibrin clots in medium and small vessels throughout the body

A

Disseminated intravascular coagulation DIC