Test 3 hematology Flashcards
blood cell production
hematopoiesis
development of red blood cells
erythropoiesis
hormone secreted by the kidney that helps the process of erythropoiesis
erythropoietin
has mitochondria and ribosome and capable of producing hem
Do not carry as much oxygen
reticulocyte
what happens to Hgb during RBC lysis
goes back into circulation
what happens to globulin during RBC lysis
reused for amino acid
what happens to iron during RBC lysis
goes to liver/spleen for reuse
what happens to bilirubin during RBC lysis
goes to liver to be conjugated and then to urine and stool for excretion
control of bleeding
hemostasis
make platelets sticky
ADP
produced by platelets and attracts more platelets to site
Thromboxane A
adds stability to plug
fibrinogen
attach to proteins
von williebrand factors
undamaged neighbor cells releases what for vasodilation
Prostaglandin PGI2
Nitric oxide
formed as plug traps circulating RBCs and macrophages
Stabilized by fibrinogen
Blood clot
the inactive precursor of plasmin
Produced in the liver
Plasminogen
is a seine protease that degrades fibrin polymers in clots
plasmin
decrease number of circulating RBCs and or abnormal Hgb
anemia
normcytic and normchromic anemias
Hemolytic
posthemorrhagic
anemia of chronic disease
macrocytic and normochromic
pernicious anemia
microcytic and hypochromic
iron deficiency
congenital or autoimmune deficiency of intrinsic factor that impaired absorption of vitamin B12
Increases abnormal RBC production
pernicious anemia