Test 1 chapter 2 Flashcards
part of the life cycle
physiological
injury or illness
pathological
Are reversible changes in the cell
cellular adaptations
is a decrease or shrinkage in cellular size
atrophy
occurs with early develpoment
Ex. the thymus undergoes atrophy during childhood
physiological atrophy
occurs as a result of decrease in workload, use, pressure, blood supply, nutrition, hormonal stimulation, and nervous stimulation
pathological atrophy
is an increase in the size of cells and consequently in the size of the affected organ
hypertrophy
is an increase in the number of cells resulting from an increased rate of cellular division
In response to injury it occurs when the injury has been sever and prolonged
hyperplasia
refers to abnormal changes in the size, shape, and organization of mature cells
Closest to neoplasia
Dysplasia
is the reversible replacement of one mature cell by another, sometimes less differentiated, cell type
metaplasia
lack of sufficient oxygen
hypoxia
an inadequate supply of blood to an organ or part of the body
ischemia
is an electorally uncharged atom or group of atoms having an unpaired electron
free radical
Two things that cause direct toxicity to a cell membrane chemically
free radicals
lipid peroxidation
when free radicals steal electrons from in lipids in the cell membrane causing cell damage
lipid peroxidation
causes of chemical cell injury
air pollutants insecticides social drugs acetaminophen dry cleaning
a decreased volume of circulating blood in the body
hypovolemia
rapid loss of the plasma membrane structure, organelle swelling, and mitochondrial dysfunction
necrosis
a regulated or programmed cell process
apoptosis
necrosis that occurs primarily in the kidneys, heart, and adrenal glands
dry: coagulative
necrosis caused by protein denaturation or irruption of aerial blood flow
dry: coagulative
necrosis that occurs in internal organs including the brain
wet: liquefactive
necrosis that involves hydrolase
wet: liquefactive
necrosis that can be caused by problems in venous blood flow
wet: liquefactive