Test 1 chapter 9

Question 1

exaggerated immune response against environmental antigens

Ex hey fever

Answer 1

allergy

Question 2

immune response against beneficial foreign tissue

Ex. transfusion, transplant rejection

Answer 2

alloimmunity

Question 3

immune response directed against “self”

Ex. systemic lupus erythematosis

Answer 3

autoimmunity

Question 4

response insufficient to protect host

Ex. AIDS

Answer 4

immune deficiency

Question 5

altered immunologic response to antigen which causes damage to host

Answer 5

hypersensitivity

Question 6

reactions that occur within minutes to a few hours are

Answer 6

immediate hypersensitivity reactions

Question 7

may take several hours to appear and are at maximum severity days after reexposure to the antigen

Answer 7

delayed hypersensitivity reactions

Question 8

most rapid and sever hypersensitivity response

Immediate

Answer 8

anaphylaxis

Question 9

reaction that are mediated by antigen specific IgE and the products of tissue mast cells
Occur against environmental antigens and are therefor allergic

Answer 9

Hypersensitivity type 1

Question 10

side effects of type 1 hypersensitivity

Answer 10

itching 
urticaria 
conjunctivitis
rhinitits
GI cramps or malabsorption 
decrease in BP
bronchospasm

Question 11

Tissue-specific
IgG or IgM binds to specific tissue antigen on cell surface and activates complement cascade which causes membrane damage and lysis
Manifestations are tissue dependent

Answer 11

Type II hypersensitivity

Question 12

antigen-antibody complexes formed in blood and deposited in vessel wall or extravascular tissue

Answer 12

Type III hypersensitivity

Question 13

mediated by T lymphocytes not antibodies

Answer 13

type IV hypersensitivity

Question 14

Type IV occurs through either

Answer 14

cytotoxic t lymphocytes or TH1 cells