swallowing and peristaltic wave Flashcards

1
Q

UES

A
  • neurogenic
  • skeletal muscle
  • constriction
  • primary peristaltic wave (swallowing)
  • anatomic sphincter that is anatomically controlled
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

LES

A
  • myogenic
  • smooth muscle
  • relaxation by VIP
  • not anatomically controlled
  • functional
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

LES

A
  • is sensitive to
  • nicotine
  • alcohol
  • chocolate
  • caffeine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

case:
joey chestnut
68 hotdogs in 10 minutes

A
  • LES
  • receptive relaxation (inhibited by atropine)
  • vagally mediated response (vagus nerve)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

case of hotdog eating contest

A
  • neostigmine
  • physostigmine
  • edrophonium (tensilon and elon)
    ALL INCREASES ACH, GI MOTILITY (receptive relaxation)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

swallowing

A
  • is a reflex controlled from the brain stem
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

case:

stroke patient damage to CN IX and X

A
  • aspiration pneumonia from loss of gag reflex

- difficulty swallowing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

basic electrical rhythm 3/min (BER)

A
  • pacemaker

- force increases not the frequency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PARASYMPATHETIC (vagal stimulation)

major force

A
  • ACh increase
  • GRP (gastrin releasing peptide) increase
  • causing distension/stretch
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

case of DM for 15 years

presented with bloating abdominal distention

A
  • diabetic gastroparesis
  • low ACh mechanism
  • parasympathetic
  • won’t feel the gastric distension/stretch due to neuropathy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

duodenum

A
  • fat (CCK) GIP
  • acid (Secretin)
  • distension
  • osmolarity (hyper)
    ALL CAUSE INHIBITS GASTRIC MOTILITY
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

stretch of duodenum

A
  • inhibits motility
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

leaves the stomach fastest

A
  • normal saline ( no fats, CHO, CHON, acid)
  • same osmolality as blood
  • normal osmolality
  • it won’t stretch the duodenum much
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

pills with gatorade gastric emptying time

A
  • 20 mins
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

gatorade vs water

A
  • water replacement can cause hypokalemic and hyponatremic

- leaves the stomach longer and take much energy to the athlete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

gatorade

A
  • has water with normal pH
  • with salt, K, Na, sugar
  • osmolality is closer to physiologic
  • leaves the stomach fast
  • rapidly absorbed
  • does not distend the stomach
17
Q

gastric motility stimulation

A
  • PARASYMPATHETIC
  • via ACh and gastrin release
  • local distension
  • DIABETIC GASTRICPARESIS INHIBITS THIS PROCESS
  • treatment METROCLOPROMIDE (reglan) increases GI motility and ERYTHROMYCIN side effect vomiting diarrhea too much motility increases GI motility
18
Q

gastric motility inhibition

A
  • low pH of the stomach inhibits release of gastrin

- feedback from duodenal overload (neuronal and hormonal)

19
Q

stomach emptying

A
  • normal saline > liquids > CHO > Protein > Fat (has a lot of calories)
20
Q

stretch of the cecum

A
  • closes the ileocecal valve
21
Q

stretch of the duodenum

A
  • closes the pyloric sphincter
22
Q

stretch of the ileum

A
  • opes the ileocecal valve
23
Q

half the volume of stool is (migrating myoelectric complex)

increase activity

A
  • GI epithelial cells
  • cleans every 5 days
  • irritable bowel syndrome (IBS)
24
Q

diabetic gastroparesis

A
  • too little activity of the migrating myoelectric activity
25
Q

case:

patient develops diarrhea abdominal pain constipation

A
  • IBS
  • hyperactivity of motilin
  • increase activity of migrating myoelectric activity
  • 90 - 120 mins
  • stopped by meal, interrupted by meals