LUNG COMPLIANCE Flashcards

1
Q

COMPLIANCE

A
  • change in volume/ change in pressure
  • proportional to change in volume
  • is inverse to elasticity (recoil when stretched)
  • EQUAL to the slope of the curve
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2
Q

lung of a 1 y/o has a

A
  • greater elasticity (recoil) new lung

- elastin, alpha 1 antitrypsin

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3
Q

lung of a 60 y/o has a

A
  • greater compliance
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4
Q

recoil

A
  • surface tension force

- La Place law

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5
Q

emphysema

A
  • deficiency in alpha 1 anti trypsin

- problem in the elastin fiber in the lung

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6
Q

surface tension force

A
  • liquid air interface

- collapsing force

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7
Q

La place Law

A
  • pressure is inverse to radius
  • decrease radius increase pressure VIA
  • air will move from high pressure to low pressure causing collapse small alveoli
  • increasing surface tension
    natural lung is in the state of collapse
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8
Q

2-3 weeks before birth

A
  • type II pneumocytes synthesized surfactant
  • DEFICIENCY respiratory distress syndrome
  • dx L:S ratio
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9
Q

SURFACTANT

A
  • surfactant decreases surface tension force
  • surfactant increase compliance
  • surfactant opposes La Place law
  • surfactant decreases capillary filtration force
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10
Q

sigmoid graph

A

Left to right

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11
Q

to the LEFT

A
  • increases the slope/compliance
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12
Q

to the RIGHT

A
  • decreases the slope/compliance
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13
Q

normal aging

A
  • losing elasticity
  • compliance increase
  • to the LEFT
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14
Q

emphysema

A
  • lost in elasticity
  • increase in compliance
  • to the LEFT
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15
Q

RDS

A
  • loss of surfactant
  • increase in surface tension force
  • loss compliance
  • to the RIGHT
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16
Q

ATELECTASIS end stage of RDS

A
  • curve more to the RIGHT

- end stage of collapse

17
Q

airway resistance

A

flow is inverse to resistance is inverse to radius

18
Q

parasympathetic nerve stimulation

A
  • bronchoconstriction
19
Q

cathecholamines

A
  • bronchodilation
20
Q

airway resistance decreases during

A
  • inspiration

- increase flow

21
Q

more negative the intracellular pressure

A
  • the lower the resistance of the airways
22
Q

short force burst blow

A
  • emptying the conductive zone (dead space)
  • (+) reflex narrowing of the bronchus, decreasing the radius of the airways (dynamic compression of the airways)
  • the flow rate is independent of effort and dependent totally in radius
  • longer time underwater