EXCITABLE TISSUE Flashcards
1
Q
potassium
A
- cation positive charges leaves negative
- concentration gradient forced potassium out of the cell
- the electrical gradient keeps potassium in (NaKATPase pump)
- efflux out of the cell is the normal conduction of K
- passive
- not energy dependent no ATP needed
- resting membrane potential is very sensitive to changes in the EXTRACELLULAR K+
- gives CARDIAC problems
2
Q
Na K ATPase
A
- needs energy
3
Q
membrane conductance
A
- ungated channels
- voltage gated channels
- ligand gated channels
4
Q
ungated channels
A
- concentration
5
Q
voltage gated channels
A
- positive (+) and negative (-) charges
- Cl-
- Na K +
6
Q
ligand gated
A
- protein transporter channel
7
Q
cell is
A
- NEGATIVE
- sodium and potassium is POSITIVE
8
Q
-70 mV
A
- keeps the potassium IN
9
Q
membrane potential
A
- -70 and - 90mV
10
Q
resting membrane potential
A
- INSIDE THE CELL -90mV more negative hyper polarization low Cl- high K + low Na + - OUTSIDE THE CELL high Cl- low K+ high Na+
11
Q
depolarization
A
- normally intracellular charge is NEGATIVE
- rapid influx of sodium INTO the cell
- fast
- increase K extracellularly influx
- cell BECOMES more POSITIVE
12
Q
repolarization
A
- based on the pump
13
Q
hyperpolarization
A
- potassium LEAVING the cell
- making THE CELL more NEGATIVE -70mV
14
Q
rhabdomyolysis
tumor lysis
hemolysis
A
- K levels in the blood is INCREASED
- INFLUX of the cell due to sudden increase in K
- depolarized the cell
- causing arrhythmia
15
Q
seizure most common cause of death
A
- hyperkalemia depolarizing the cell then death occurs
