digestive process Flashcards

1
Q

protein has no taste

A
  • due no chymotrypsin, trypsin in saliva

- trypsin essential

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2
Q

essential in stomach is

A
  • intrinsic factor

- absorb B12 in the terminal ileum

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3
Q

pancreas

A
  • essential
  • lipase
  • amylase
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4
Q

gallbladder

A
  • bile and lipase for fat absorption

- starve to death

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5
Q

small bowel

A
  • disaccharidases (lactase, lactose intolerance; sucrase, sucrose intolerance; maltase 2 glucose breakdown, trehalase 3 glucose breakdown)
  • only MONOSACCHARIDES CAN BE ABSORBED by FACILITATED DIFFUSION
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6
Q

driving the entire absorption

A
  • NaKATPase (active transport splitting energy)
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7
Q

not dependent in sodium reabsorption

A
  • FRUCTOSE (independent of sodium reabsorption)
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8
Q

which of the following does not affect secondary active transport

A
  • INSULIN

- it does not affect glucose absorption in GUT and KIDNEY

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9
Q

INSULIN

A
  • affects transport in adipose tissue and resting muscles
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10
Q

AMINO ACIDS

A
  • are transported by SECONDARY ACTIVE TRANSPORT liked to SODIUM
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11
Q

absorption of lipids

TRIGYCERIDE

A
  • bile micelles (emulsify)

- pancreatic lipase will absorb it into 2 free fatty acids and position 2 monoglyceride

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12
Q

absorption of fats is by

A
  • diffusion

- chylomicrons brings the fat to thoracic duct for mixing

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13
Q

absorption of fats

lipase breaksdown

A
  • triglyceride
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14
Q

absorption of fats

cholesterol esterase

A
  • breaks up into cholesterol and free fatty acid

reesterified into chylomicron that goes into the lymph and dumps it into circulation by the process of DIFFUSION

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15
Q

ABSORPTION

duodenum

A
  • most divalent ions (Fe, Ca, Mg)
  • water soluble vitamins
  • Fe+
  • Mg+
  • Ca+
  • celiac disease (IRON DEFICIENCY)
  • chronic pancreatitis(NO IRON DEFICIENCY because the don’t need pancreatic enzymes)
  • stool are greasy, foul, floating etc.
  • malabsorption of fat soluble vitamins ADEK
  • weight loss due to fat malabsorption
  • osteoporosis Vit D malabsorption
  • easy bruising
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16
Q

CELIAC DISEASE vs CHRONIC PANCREATITIS

A
  • celiac disease (IRON DEFICIENCY)

- chronic pancreatitis (NO IRON DEFICIENCY because the don’t need pancreatic enzymes)

17
Q

JEJUNUM

A
  • overall
  • net absorption of water and electrolytes
  • site where HCO3 IS ABSORBED
18
Q

distal ILEUM

A
  • BILE SALTS ABSORPTION
  • VITAMIN B12 and INTRINSIC FACTOR ABSORPTION
  • ONLY IN ILEUM
19
Q

COLON

A
  • only site excrete 100% POTASSIUM; HCO3 (duodenum also excrete and absorb)
  • NO DIGESTION PROCESS/ENZYME
  • DIARRHEA
  • site of action for ALDOSTERONE
  • absorb most of the water
20
Q

case:

site of development of diarrhea where patient presents with low serum potassium and HCO3

A
  • COLON
21
Q

ALDOSTERONE works

A
  • on the COLON

- and DISTAL TUBULE

22
Q

case:

patient with HEMOCHROMATOSIS site of defect

A
  • DUODENUM
23
Q

case:
IRON OVERLOAD
HFe gene site of defect

A
  • DUODENUM
24
Q

case:

IRON deposition in the heart, liver, skin, gonads site of defect

A
  • DUODENUM
25
Q
case:
difference between 
CHRONIC PANCREATITIS 
vs
WHIPPLES DISEASE
TROPICAL SPRUE
CELIAC DISEASE
A
  • DUODENAL MALABSORPTION OF IRON