Support Tissues Flashcards
Give examples of liquid support tissues
Cells - blood cells
Extra cellular matrix - plasma and lymph
When observing liquid support tissues, most cells need a special stain to observe what. What do these release?
Cytoplasmic granules
Release histamine
What is the function of the basal membrane?
Cell adhesion
Diffusion barrier
Regulate growth
How is the basement membrane adhered to the basal lamina?
Hemidesmosomes
What are the functions of support tissue?
Provide mechanical stability
What is connective tissue made from?
Cells and extracellular matrix
What is mesenchyme?
Connective tissue found in the embryo
What is extracellular matrix? What does it do?
Fibrous proteins and extracellular molecules
Provide support to surrounding cells
Which cells synthesise ECM? What do they mature to and how are these different?
Fibroblast
Fibrocytes - dormant, reduced in volume, elongated
Extra cellular fluid is composed of..
Collagen fibres
GAGs - glucosaminoglycans
Collagen attracts acid stain. Why?
It is positively charged
What are the 2 main categories of ordinary connective tissue?
Loose
Dense
What are the 3 types of loose connective tissue?
Areolar
Adipose
Reticulum
What are the 3 types of dense connective tissue?
Regular
Irregular
Elastic
What does loose areolar connective tissue do? Where is it found?
Support epithelial lining of GI, respiratory and urinary tracts
Also found between cells of other organs
What are the 2 types of loose adipose connective tissue?
White fat - energy reserve or insulation
Brown fat - produces heat in neonates, many mitochondria
What is loose reticular connective tissue? What does it do?Where is it found?
Type of collagen
Acts as a filter
Liver and lymphatic system
Where is regular dense CT found? What does it do?
Tendons/ligaments
Runs in same direction as muscle to provide strength and support
What does dense irregular CT do?
Surrounds organs
What does dense elastic CT do? What is it composed of?
Allows stretching of areas e.g. lungs/arteries
Attaches tendons
Composed of protein elastin
What are specialised connective tissues? What are they produced by? What are the 3 types?
Cartilage
Produced by chondroblasts and chondrocytes
Fibrocartilage, hyaline cartilage, elastic cartilage
Give an example of where fibrocartilage is found. What does it do? What is it composed of?
Intervertebral disc
Allows support and flexibility
Lots of collagen
Where is hyaline cartilage found? What does it do? What shape are the cells?
Joints
Provides support where bone is not required, save weight
Round
Where is elastic cartilage found?
Flexible fibres e.g. pinna
What shapes can bones be? What is the shaft of a bone called? What about the ends?
Long or flat
Diaphysis
Epiphysis
Describe the cells involved with bone production and remodelling
Osteogenic cells Form osteoblasts (make new bone tissue and matrix) Form osteoclasts (maintain, reabsorbed and breakdown bone tissue)
What penetrates into compact bone? What is the bone cavity filled with?
Blood vessels
Nerves
Lymphatic vessels
Marrow
What does red marrow produce? Where is it found? What about yellow marrow?
RBCs in young animals
Adult animals, adipose tissue can be used for haematopoiesis
What is the Haversian system?
Functional units of compact bones - made of layers
Remodelled throughout life
What is bone derived from in the embryo? What are the two types of ossification called? (Both lead to same type of flat bone)
Mesenchyme
Intramembranous ossification
Endochondral ossification
Describe intramembranous ossification
Within the membrane
Mesenchymal cells differentiate into osteoblasts
Osteoblasts lay down osteoid which is calcified into bone
What is osteoid?
Bone matrix
Describe woven bone
No organised layers surrounding blood vessels
Weak
Describe endochondral ossification
Mainly long bones, develop inside cartilage
Bone first made of solid hyaline cartilage which enlarges as foetus grows
Woven bone remodelled into lamellar bone
Formation starts at ossification centres. Chondrocytes die and become hallow
Secondary centres of ossification lengthen the bone
What is appositional growth?
The growth of cartilage whilst bone grows, due to addition of more ECM