Salmonella

Question 1

What type of bacteria is salmonella?

Answer 1

Gram negative
Facultative Anaerobes
Rod shaped
Foodborne zoonoses (eggs, milk, meat)

Question 2

What diseases can salmonella cause?

Answer 2

Enteritis

Typhoid

Question 3

What does inflammatory gastroentiritis lead to?

Answer 3

An influx of neutrophils

Question 4

Where abouts in the body does salmonella become pathological? What does it have to deal with?

Answer 4

Ileum

Acid ph, intestinal flow

Question 5

How does salmonella cause disease?

Answer 5

Secretes protein to alter host cell function
Innate immune system recognises bacterial PAMPs
Immune system initiates inflammatory response
Salmonella can survive in macrophages so travels through lymphatic system to spleen/liver
Undergoes intracellular replication

Question 6

If salmonella is uncontrolled, what does it lead to?

Answer 6

Septicaemia and death

Question 7

What are bacterial PAMPs? What are they for salmonella?

Answer 7

Bacterial pathogen associated molecular patterns

Flagella and lipopolysaccharides

Question 8

Which species of salmonella causes typhoid?

Answer 8

Salmonella paratyphoid