Blood Histology Flashcards

1
Q

What are the functions of blood plasma?

A

Carry nutrients, hormones and waste products
Maintain blood fluidity
Maintain oncotic pressure
Blood clotting

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2
Q

What is packed cell volume?

A

% of blood occupied by cells

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3
Q

How big are erythrocytes? How are they produced? Which hormone regulates this?

A

1/4 size of a normal cell
Haematopoiesis
Haematopoietin

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4
Q

Where does haematopoietin take place?

A
Bone marrow 
Yolk sac
Liver
Thymus
Spleen
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5
Q

Some species/breeds have nucleated RBCs. What affect does this have?

A

More rigid

Less haemoglobin

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6
Q

What are the precursors of erythrocytes? What do these then form? Describe their organelles.

A

Erythroblasts - contain nucleus

Reticulocyte - no nucleus, but organelles

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7
Q

Old cells are fragile and less flexible. Which cells recycle and remove these?

A

Macrophages

Type of phagocyte

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8
Q

What are the parts to the blood smear?

A

Head
Body
Monolayer
Feathered edge

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9
Q

Describe the structure of haemoglobin

A

4 polypeptide chains each with a haem group

Centred by an iron ion

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10
Q

Describe the polypeptide chains found in adult and foetal haemoglobin.

A

Adult - 2a, 2b

Foetal - 2a, 2 gamma

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11
Q

How is CO2 transported in blood?

A

Most chemically modified as carbonate
Some protein bound
Few dissolved in plasma

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12
Q

What are the two types of bone marrow?

A

Red marrow

Yellow marrow

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13
Q

Where is red marrow found?

A

Long, flat bones

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14
Q

Describe yellow marrow

A

High number o dat cells

Can be converted to haematopoietic tissue if needed

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15
Q

What is the function of leukocytes?

A

Immunity and inflammation

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16
Q

Where are leukocytes produced? What stimulates their maturation?

A

Bone marrow

Cytokines produced by damaged/inflamed tissue

17
Q

Which WBC is most common?

A

Neutrophil

18
Q

Name the 5 common leukocytes

A
Neutrophil
Basophil
Eosinophil
Monocyte
Lymphocyte
19
Q

What are granulocytes? Which WBCs are these?

A

WBC containing granules and polylobed nuclei

Neutrophil, basophil, eosinophil

20
Q

What do platelets do? What do non-mammals have instead? What is different about these?

A

Stop bleeding by adhering and aggregating

Thrombocytes (platelets with a nucleus)

21
Q

How are platelets produced? Which hormone regulates this?

A

Thrombopoiesis

Thrombopoietin

22
Q

How long is the life span of a platelet?

A

10 days

23
Q

Horses have 2 leukocytes which are different and lobulated looking. Which are these?

A

Eosinophil

Basophil