Storing and Using Genetic Information Flashcards
Define phenotype
Outward physical manifeetwtion of an organism
Define genotype
Full hereditary info of an organism even if it’s not expressed
What does the function of protein depend on?
The sequence of amino acids
What are the two groves of the double helix?
Major and minor groove
Why do the base pairs come together?
Hydrogen bonding
What name is given to the mixture of DNA, proteins and RNA which packages DNA into the cell
Chromatin
Which two forms is chromatin divided into?
Heterochromatin
Euchromatic
Is heterochromatin the condensed or extended for of chromatin?
Condensed form
Is euchromatic the condensed or extended for of chromatin?
Extended form
What do the processes of transcription and replication need the strands of DNA to do?
Separate to allow the enzymes access to the DNA template
Which two mechanisms make chromatin more accessible?
Enzyme modification of histones
Displacement of histones by chromatin remodelling complexes
What can pose barriers to enzymes trying to assist w transcription/ replication?
Nucleosomes
Folding of chromatin
In which direction is DNA replicated?
5 to 3 direction
In which stage of replication are the chromosomes most visible?
Metaphase
What are exons?
Coding regions of DNA
What are introns?
Non-coding regions of DNA
Every three bases is known as a…?
Codon
What does each codon code for?
An amino acid
Four bases combine to give how many possible codons?
64
(4 to the power of 4)
In reality, how many codons are there?
Twenty as only twenty amino acids they can code for
What would a mutated haemoglobin gene cause?
Sickle cell anaemia
How is mRNA produced?
Transcribed from DNA
What does mRNA do?
Carry info for protein synthesis
How is DNA turned into mRNA?
Transcription
What process happens to mRNA
Alternative splicing
How does mRNA become a DNA sequence?
Translation
What is rRNA?
A component of ribosomes
Where is rRNA transported and what happens when it’s there?
Transported to the cytoplasm where it is combined with protein to produce ribosomes