STI Large Lecture

Question 1

2 causes of painless genital ulcer

Answer 1

clamydia L1-L3

primary syphilis

Question 1

What is the most prevalent cause of painful genital ulcer disease?

Answer 1

HSV

Question 2

Where does HSV establish latency?

Answer 2

in the dorsal root ganglia

Question 3

What is the empiric treatment for HSV?

Answer 3

acyclovir

*can use other cylcovirs

Question 4

How long do you administer clycovirs for?

Answer 4

7-10 days

Question 5

What is the first test performed for painful genital ulcer?

Answer 5

suspect herpes so perform swab for HSV PCR

*HSV PCR can determine between type 1 and 2

Question 6

Some overlap between chlamydia and gonorrhea

Answer 6

urethritis, PID, trachoma and cervicitis

Question 7

LGV

Answer 7

ulcerative disease of genital area most commonly caused by chlamydia L1-L3

Question 8

How do you test for N. gonorrhea?

Answer 8

NAAT testing

Question 9

What type of bacteria is N. gonorrhea?

Answer 9

gram negative diplococci

Question 10

treatment for gonorrhea

Answer 10

ceftriaxone

*also treat for chlamydia

Question 11

treatment for chlamydia

Answer 11

doxycycline (preferred)

macrolides (given during pregnancy)

Question 12

What is the hallmark symptom of syphilis?

Answer 12

maculopaplar rash on hands + feet

Question 13

How long does painless ulcer take to form in syphilis?

Answer 13

3-4 weeks

Question 14

When does neurosyphilis develop?

Answer 14

can develop at any point

Question 15

What is the treatment for syphilis?

Answer 15

penicillin

Question 16

Why do we not perform darkfield microscopy for syphilis?

Answer 16

requires biopsy

Question 17

VDRL + RPR

Answer 17

non-treponemal tests

tells you if a disease is active

Question 18

FTA-ABS

Answer 18

treponemal test

tells if you’ve ever been exposed to syphilis

Question 19

What test is always positive once exposed to syphilis?

Answer 19

FTA-ABS

Question 20

What should you do if someone has syphilis during pregnancy but is allergic to penicillin?

Answer 20

de-sensitive them

Question 21

How do -cyclovirs work?

Answer 21

competitive inhibitors of DNA polymerase by being a nucleoside analog

Question 22

Which drug is associated with thymidine kinase?

Answer 22

acyclovir