Intro to Renal Function Flashcards
Low protein diet effects on BUN ….
lowers BUN
BUN
blood urea nitrogen
Upper GI bleed …
increases BUN
Hypotension w/ low renal perfusion …
high BUN
High dose corticosteriod …
increases BUN
(induces a catabolic state which breaks down protein into urea )
Tetracycline antibiotics
high BUN
induces a catabolic state
What is creatinine dependent on?
body mass
OCT
secretes creatinine into tubulues
How is creatinine formed?
formed from creatine
this is an anabolic process
Anabolic steroids effect on Cr
high Cr
LE amputation effect on Cr
lower Cr (less muscle mass)
OCT inhibitor
High Cr
(cannot secrete creatinine into tubule)
Creatine supplements lead to …
transient increases in creatinine
What is the best measure of kidney function?
GFR
When can you calculate GFR?
only when creatinine is in a steady state
do NOT calculate if creatinine has changed over past couple days