Step 3 intoxi & medication Flashcards

1
Q

cyanide vs carbon monooxide?

A

Cyanide doesn’t respond to 100% O2

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2
Q

이거 왜 이렇고 언제 이렇지?

A

cyanide intoxication. “ Too much oxygen in the BLooD!”:

The tissue cannot use O2 in the blood. The blood become bright bright re

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3
Q

이거 뭐임? 급성중독시 치료?

A

methamphetamine 히로뽕 - lorazepam 으로 치료

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4
Q

카바카바 ??

A

KAVA is liver injury

리바까바 막까.

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5
Q

aspirin intoxication?

A

Hyperthermia, tinnitus, confusion, hepatotoxicity, Acidosis and compensating Hyperrespiration.

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6
Q

Tx for ethylen glycol?

A

mainly fomepizole,. IV ethanol

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7
Q

ethylene glycol 은 왜 쳐지게?

A

metabolic acidosis

anion gap acidosis 지

gap 이 있네. 고저차가

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8
Q

Acetylcholine 은 para or sympa?

A

모든 곳에 관여한다. 그래서

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9
Q

muscarinic 은 어느쪽? nicotinic 어느쪽?

A

nicotinic 은 para/sympa 모두지만 muscarinic 은 only para …. 마스크

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10
Q

organophophate 치료 제제와 제한 시간

A

atropine, 2PAM (Pralidoxime) 은 48시간이내
이틀 …

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11
Q

cyanide posioning tx?

A

Treatment involves first administering nitrites and following with thiosulfate, although hydroxycobalamin can also be used.

Exposure typically occurs via administration of nitroprusside (a cyanide

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12
Q

carbon monooxide poisioning tx

A

O2

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13
Q

5개쯤 이야기해봐라. snake 가 많네.

A

Primary snake- sclerosing cholangitis 는 UC 가 biliary 에 간거 (rusty canon)

Beads on a string bile duct MRCP

medieum size bile duct …ascending

P-ANCA

onion skinning bile duct lesion

ADEK diarrhea and malabsorption

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14
Q

atropine 은 기전? / 중독시 치료? / 언제 쓰나? /

A

anti-muscarinic/ physiostigmine 이 치료/ 아트로피카나/ bradycardia 치료

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15
Q

Para sympathetic vs sympathetic 증상

A

Para는 줄줄 싸고 눈물 흘리고 긴장 풀리고 소화하고 anal, urethral sphinter 가 relax

긴장해서 소변보고 싶은건 bowel sensory signal change이다. sympathetic direct 기전 아니다.

Sympathetic : 긴장: HR, BP 증가, 장운동 방광운동 억제, sphincter들은 모두 contact

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16
Q

Botulism toxin mchanism ?

A

콜라를 못꺼냄. Blocks acetylcholine release in presynaptic neurons

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17
Q

언제 쓰이는 약일까?

A

목돌아간 히드라. - diphenhydramine 은 acute dystonia 치료.

1st gen anti-histamine

18
Q

여기 콜라병이 왜이래 많노

A

Abundance of acetyl-cola / dumpster가 닫켜 있어서 콜라를 못버림.

Organophosphates** inhibits acetylcholinesterase** leading to acetylcholine excess

19
Q

TB drug and CYP 450?

A

Rifampin Induces CYP450 enzymes

20
Q

INH S/E

A

CYP를 못하게 하는 beer bong 이랜다… 그리고 pyramid … B6 pyridoxine def

21
Q

문제에 많이 나오는 CYP450 으로 metablize되서 약먹을때 조심해야하는 약들 ?

A

warfarin / OCP/theophylline

오C피
theoPhylline
와이파린

CYP 안에 다 있다.

22
Q

P450 Inducer
Griseofulvin
Phenytoin
Carbamazepine
Rifampin
Barbiturates
Chronic Alcohol Use
St. John’s Wort

술고래 존아저씨 카에 그리스칠하고 있고 차안에는 라이플, 담배피고 있지

Carbamazepine
phyenytowing 토잉하는
John’s wort
rifle rifampin
smoking
Griseofulvin - grease helps engines work = CYP450 inducer

cytochrome

A

P450 Inhibitors
Quinidine
Ciprofloxacin
Isoniazid
Grapefruit Juice
Acute Alcohol Use
Erythromycin (Macrolide)
Indinavir
Cimetidine
Sulfonamides
Ketoconazole
Amiodarone

23
Q

이제목이 뭐라고? hyponatremia …. primary polydipsia 에 있ㄴㅏ 없다?

A

Hyponatremia

primary polydipsia는 기본적으로 hyponatremia인거지.

24
Q

aminoglycoside 의 target?

A

aerobic Gram negative - 공기불어넣고 있고 벽이 벌겋네

25
Q

B6 는 뭔고

A

Bee stick B Six
피라미드 쌓고 있네

26
Q

thiamine은 B ?

A

Thigh …. Th1gh B1

27
Q

mean/ mode/ median

A

median은 그 이름 처럼 언제나 중간

28
Q

preclude

A

prevent from/ 안한다고

29
Q

RA medication tx

A

Meat stick - MTX 로 시작하는 DMARDs 해서 TNF alpha inhibitor 등

30
Q

타이레놀 과용량때 쓰는 NAC 의 mechanism?

A

Glut 머슬을 회복시켜주는 나쵸!!!

Glutathione 의 전구물질!! => 운동으로 glut머슬이 피곤할땐? 나쵸

31
Q

CYP inducer

A

존아저씨의

Carbamazepine
phyenytowing 토잉하는
John’s wort
rifle rifampin
smoking
Griseofulvin - grease helps engines work = CYP450 inducer

32
Q

CYP reducer

A

못가도록 바퀴빼버린 트럭 inhibitor

아미고다론
마크로 라이드
CCB
솔방울 zole
grapefruit juice
INH
cimetidine

33
Q

CYP 에 의해 metabolism 되는 약들

f

A

Beta blocker
Warfarin
OCP
Statin
theophyllin
anti psy

Contraceptions
Yfarin
psyctics

Statin
Theophylling
Beta blocker

34
Q

diphenhydramin? 은 왜 노인에서 안쓰나

A

마스크를 벗고 있어
1gen anti histamine은 Anti cholinergic effect가 있어서 노인에서 USMLE에서는 안쓰지

35
Q

ASD vs PTSD

A

달이 사이에 있네. 1달

36
Q

???

A

renal amyloidosis => nephrotic synd by chronic inflammatory dz (RA ) / or MM

armored lady on nephropathy

37
Q

tenofovir S/E

A
38
Q

anti psychotics 부작용

A

배나왔지. metabolic synd/ hyperprolactinemoia / agranulocytosis / neuroleptic malignancy syndrome

39
Q

serum sickness like synd vs serum sickness synd

A

Serum sickness-like reaction (SSLR) is an immune response that can cause a rash, fever, joint pain, and other symptoms. It’s often triggered by a drug, but can also be caused by an infection or vaccine. SSLR is similar to classic serum sickness, but SSLR is usually caused by drugs and doesn’t produce the same antigen-antibody complexes

40
Q

polyarteritis nodosa 는 어떤 환자에게 잘오나?

A

hePANtiis B