SPMSVR

Question 1

First line drug against complicated UTI in pregnanct women?

Answer 1

Amoxicillin

But also nitrofurantoin, ceftriaxone and imipenem

Question 2

Drugs effective against pseudomonas aeruginosa ?

Answer 2

Piperacillin, ticacillin, ceftriaxone, aztreonam, carbapenems, aminoglycosides, ciprofloxacin

Question 3

Antibiotics used for C.difficile superinfections?

Answer 3

Vancomycin, metronidazole, and fidaxomycin

Question 4

Antibiotics that MRSA is sensitive to?

Answer 4

Ceftaroline, vancomycin, clindamycin, linezolid, doxicycline, and daptomycin

Question 5

Administration of aminoglycosides?

Answer 5

IV, IM or subcutaneously but NOT ORALLY

Question 6

Antibiotics that work on the 30s and are bacteriostatic?

Answer 6

Tetracylines

Question 7

Antibiotics against against SIADH?

Answer 7

Demeclocycline

Question 8

First line drug against treponema pallidum?

Answer 8

Penicillin G

Question 9

First line drug against chlamydia infection?

Answer 9

Amoxicillin

Question 10

Drug that inhibits peptidyl transferase?

Answer 10

Macrolides, chloramphenicol and streptogramins

Question 11

Mechanism of action of cilastatin, probenecid and clavulonate?

Answer 11

Cilastatin->Inhibits dehydropeptidase, and thus inhibits renal metabolism of imipenem and increases the concentration of imipenem
Probenecid-> Inhibits renal excretion of several antibiotics (also increases excretion of uric acid)
Clavulonate-> Inhibits beta lactamases and makes the bacteria more sensitive to antibiotics

Question 12

Antibiotic that can be used in meningitis?

Answer 12

Chloramphenicol, penicillin G, ampicillin, and ceftriaxone

Question 13

Bacteriostatic antibiotic against TB?

Answer 13

Ethambutol

Question 14

Antibiotic against leigionnairs disease?

Answer 14

Azithromycin, erythromycin

Question 15

Drug against mycobacterium avium-intracellulare?

Answer 15

Azithromycin, clarithromycin, ethambutol, rifampin, and ciprofloxacin

Question 16

Antifungal antibiotics?

Answer 16

Nystatin and natamycin

Question 17

Antifungals used to treat cushings disease?

Answer 17

Fluconazole and ketoconazole (they inhibit cytochrome p450 and steroid synthesis)

Question 18

Antifungal that may treat vaginal candidiosis in 1 pill?

Answer 18

Fluconazole

Question 19

Drugs against systemic candidiasis (at least 3)?

Answer 19

Amphotericin B, fluconazole, voriconazole, caspofungin, and flucytosine

Question 20

Drugs against onychomycosis (at least 3)?

Answer 20

Itraconazole, naftifine, terbinafine and ciclopirox

Question 21

Antifungal that increases membrane permeability?

Answer 21

Polyene antibiotics (amphotericin B, natamycin, nystatin)

Question 22

Drugs for P. jeroveci?

Answer 22

Trimethoprim-sulfomethoxazole, atovaquone, pentamidine, dapsone, and prednisone