39 Protein synthesis inh. (Adverse effects)

Question 1

Aminoglycosides

Answer 1

Nephro and ototoxicity

Question 2

Tetracyclines

Answer 2

Discoloration of the teeth and hypoplasia of the enamel, severe nephro- and hepatotoxicity, photosensitivity, erythema and sunburn

Question 3

Macrolides

Answer 3

Stomatitis, heart and uncoordinated peristalsis

-Erythromycin->Tinnitus and hearing loss, thrombophlebitis

Question 4

Ketolide antibiotic (Telithromycin)

Answer 4

GI toxicity, Hepatotoxicity, Prolongation of QT, resp failure in pt with myasthenia gravis, visual disturbances and loss of consciousness

Question 5

Clindamycin

Answer 5

Superinfections of C.difficile

Question 6

Chloramphenicol

Answer 6

Gray baby syndrome (cyanosis, weakness, respiratory depression, shock), bone marrow suppression (dose dependent anemia, and rare aplastic anemia)

Question 7

Streptogramin drugs

Answer 7

Infusion site inflammation, arthralgia, and myalgia

Question 8

Linezolid

Answer 8

Hematologic toxicity