30 NSAIDs (Adverse effects) Flashcards
1
Q
Non-selective COX-2 inhibitors
A
GI bleeding, peptic ulcers, renal and hepatic dysfunction, lithium toxicity, hyperkalemia, platelet inhibition, and premature closure of ductus arteriosus
-Salicylates lead to Raye syndrome in virus infected children
2
Q
COX-3 Inhibitors
A
Fewer GI problems, but severe hepatic necrosis
3
Q
Selective COX-2 inhibitors
A
No GI toxicity, increased risk of cardiovascular events and rashes (SJS, TEN, EM)
4
Q
Uricosuric drugs
A
GI, renal and hematologic adverse effects
5
Q
Xanthine oxidase inhibitors
A
Hepatitis, and skin rashes
6
Q
Catabolic enzyme preparation
A
Life-threatening allergic reactions
