36 Bones (Adverse effects) Flashcards
Calcium supplements
Constipation and modestly increased in MI
Vitamin D supplements
Hypercalcemia and hypercalciuria
Bisphosphonates
Esophageal erosion when given orally, GI-distress, Atypical femoral fractures (long-term use), and osteonecrosis of the jaw
Teriparatide
Increased risk of osteosarcoma
Denosumab
Musculoskeletal pain, increased risk of infections, hypocalcemia, and osteonecrosis of the jaw
Estrogens
Breast tenderness, headache, edema, changes in libido, hypertension, thromboembolic diseases, gallbladder disease, and increased risk of breast
Raloxifene
Hot flashes and increased risk of thromboembolic diseases
Sodium fluoride
Osteosclerosis, formation of demineralized bone and GI distress
Strontium ranelate
Minor GI distress and increased risk of thromboembolic diseases