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Heme boards > Splenic marginal zone lymphoma > Flashcards

Splenic marginal zone lymphoma Flashcards

1
Q

Morphology of lymphocytes on smear in splenic marginal zone lymphoma

A
  • villous projections
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2
Q

Management of splenic MZL

A

Watch and wait for most patients (indolent lymphoma management)
IF indication for treatment
BR
Single agent rituxan
Splenectomy w/ pre-op vaccinations

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3
Q

Clinical features

A

Splenomegaly + absence of lymphadenopathy

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4
Q

Splenic MZL immunophenotype

A

*similar to CLL
CD5+, CD10+, CD23+, CD103+, CD200 negative
CD19
**CD20 bright (as opposed to CLL)

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Heme boards (58 decks)

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