Other Flashcards
Management of acute GVHD affecting the GI tract
- nonabsorbable oral steroid (budesonide)
+ systemic glucocorticoid
Management of erythrocytosis in patient with transplanted kidney
ACE inhibitor
Most common mutations in CMML
- TET2
- SRSF2
- ASXL1
CMML treatment
IF high risk, HMA bridge to transplant
IF low risk, observation
Once needing treatment HMA vs. hydrea
Pathophysiology of cerebellar neurotoxicity with cytarabine
Widespread loss of purkinje fibers
clinical benefit of early vs. delayed transplant in myeloma
PFS alone
DOAC management perioperatively
- IF urgent surgery, reverse DOAC
- IF low/moderate bleeding risk, hold for one day before
- IF high bleeding risk, omit 2 days before
Definition of GVHD overlap syndrome
simultaneous features of both chronic and acute GVHD
Advanted of BuCy conditioning vs. BuFlu
- reduced time to t cell engraftment
Burr cells on peripheral smear
see photo
Burr cell differential
- ESRD
- Liver disease
- Pyruvate kinase deficiency
PKD inheritance
autosomal recessive
drug contrandicated with methotrexate
NSAIDS (reduce renal clearance)
Site of hematopoiesis in gestation at 5/6 months
l*iver
bone marrow
Peripheral smear of hereditary stomatocytosis
- see photo online
Management of patient on ganciclovir for CMV and levels are uptrending
Continue (takes 1-2 weeks for levels to decline after starting treatment)
Management of acquired VWF deficiency
recombinant VWF
What is idecabtagene?
idecabtagene vicleucel (ide-cel)
Least important antigen for hemolytic transfusion reaction
Lewis antigen
Etiology of CLL patient treated with FCR and presenting with dry cough, fever, hypoxia
PJP oneumonia
Other SE of IVIG to be aware of
aseptic meningitis
What to do if you’ve caused hyperviscosity in LPL patient with rituximab
PLEX
What to think with prolonged thrombin time
low fibrinogen
Gaucher disease treatment
IF cytopenias or significant splenomegaly, enzyme replacement therapy