SP4: Liver Diseases Flashcards
What are the right and left nodes of the liver separated by?
Falciform ligament
How many segments make up the liver?
8 segments
What does the hepatic artery bring to the liver?
Oxygenated blood
What does the hepatic portal vein bring to the liver?
Nutrients
How does the gallbladder connect to the common hepatic duct?
Via the cystic duct
What cell is liver tissue made up of?
Hepatocytes
What are sheets of hepatocytes separated by?
Sinusoids
What are the 3 main functions of the liver?
- Metabolic function
- Synthesis function
- Storage function
What are the 4 main symptoms of liver disease?
- Jaundice
- Oedema
- Ascites
- Cerebral dysfunction
What is jaundice?
Raised serum bilirubin, with bilirubin deposition in tissues
What are the 2 types of jaundice?
- Unconjugated
- Conjugated
Explain prehepatic jaundice? (3)
- Excess bilirubin production
- Internal bleeding
- Ineffective erythropoiesis
Explain intrahepatic jaundice? (3)
- Impaired conjugation
- Impaired excretion of bilirubin
- Reduction in bilirubin uptake
What can cause post hepatic jaundice?
Extrahepatic biliary obstruction
ie Gallstones, cancer etc
What are some hepatic causes of oedema? (2)
- Portal hypertension
- Hypoalbuminaemia