SODIUM BICARBONATE Flashcards
CLASS
ALKALINIZING AGENT
ACTION (2)
BINDS WITH H+ IONS TO FORM WATER AND CARBON DIOXIDE & WITH CO2 EXCRETED BY THE LUNGS DECREASES THE ACIDITY OF THE BLOOD
CAUSE POTASSIUM TO SHIFT INTO CELLS
INDICATIONS (6)
PATIENTS WITH KNOWN PERSISTING METABOLIC ACIDOSIS (DKA) IIa
HYPERKALEMIA I
TRICYCLIC ANTIDEPRESSANT OVERDOSE IIa
PHENOBARBITAL OVERDOSE
ALKALINIZE THE URINE IN DRUG OVERDOSES
AFTER PROTRACTED ARRESTS/LONG RESUSCITATION
DOSAGE/ ROUTE
SEE HAWAII SO AND FOLLOW ACLS ALGORITHM (tca overdose)
STANDARD PREP
50 mEq / 50 cc preloaded syringe
PEDS DOSE
SEE HAWAII SO AND FOLLOW PALS ALGORITHM
CONTRAINDICATION (2)
METABOLIC ALKALOSIS
RESPIRATORY ALKALOSIS
SIDE EFFECTS (5)
PARADOXICAL INTRACELLULAR / TISSUE ACIDOSIS DUE TO CO2 GENERATION AND INADEQUATE VENTILATIONS TO RID CO2 WHICH READILY DIFFUSES ACROSS CELL MEMBRANES
HYPERNATREMIA FROM LARGE SODIUM LOAD
HYPEROSMOLARITY FROM LARGE SODIUM LOAD
MAY SHIFT OXYHEMOGLOBIN DISSOCIATION CURVE TO THE LEFT WHICH CAUSES A DECREASE IN THE RELEASE OF 02 BY HGB TO THE TISSUES
METABOLIC ALKALOSIS
PRECAUTIONS
DOSING SHOULD IDEALLY BE GOVERNED BY ABG VALUES
BICARBONATE THERAPY SHOULD BE CONSIDERED ONLY AFTER DEFIB., CPR, ETT, VENTILATION AND TRIAL OF EPINEPHRINE
OVERLY AGGRESSIVE FIELD USE MAY RESULT IN METABOLIC ALKALOSIS
DO NOT MIX WITH CALCIUM CHLORIDE! PRECIPITATES IN LINE IF NOT FLUSHED WELL.