DOPAMINE (INTROPIN)

Question 1

CLASS

Answer 1

CATECHOLAMINE

SYMPATHOMIMETIC

Question 2

ACTIONS

Answer 2

DOSE DEPENDENT SYMPATHOMIMETIC

AT LOWER DRIP RATES OF 1-2 UG/KG/MIN, STIMULATE DOPAMINERGIC RECEPTORS TO PRODUCE CEREBRAL, RENAL, AND MESENTERIC VASODILATION

AT DRIP RATE OF 2-10 UG/KG/MIN, B1 EFFECTS PREDOMINATE (PREDOMINANTLY INOTROPIC EFFECT) WITH ALPHA EFFECTS BEGINNING (VASOCONSTRICTION)

AT DRIP RATES 10-20 UG/KG/MIN ALPHA EFFECTS PREDOMINATE WITH RENAL, MESENTERIC, AND PERIPHERAL ARTERIAL, AND VENOUS VASOCONSTRICTION WITH MARKED INCREASE IN SVR (SYSTEMIC VASCULAR RESISTANCE)

AT DRIP RATES > 20 UG/KG/MIN ALPHA EFFECTS SIMILAR TO NOREPINEPHRINE PREDOMINATE WITH MARKED PERIPHERAL VASOCONSTRICTION AND TACHYCARDIA

Question 3

INDICATIONS

Answer 3

CARDIOGENIC SHOCK

OTHER TYPES OF SHOCK AFTER ADEQUATE FLUID RESUSCITATION

SYMPTOMATIC BRADYCARDIA UNRESPONSIVE TO ATROPINE OR EXTERNAL PACEMAKER

Question 4

CONTRAINDICATIONS

Answer 4

HYPOVOLEMIA BEFORE FLUID RESUSCITATION

PTS. TAKING MONAMINE OXIDASE INHIBITORS

PHEOCHROMOCYTOMA (CAN PRECIPITATE HYPERTENSIVE CRISIS)

UNCORRECTED TACHYARRHYTHMIAS

Question 5

SIDE EFFECTS

Answer 5

TACHYARRHYTHMIAS

HTN

PRECIPITATE MYOCARDIAL ISCHEMIA

TISSUE NECROSIS WITH EXTRAVASTION (INFILTRATION)

Question 6

PRECAUTIONS

Answer 6

MONITOR VS AND EKG

STOP INFUSION IF DIASTOLIC PRESSURE RISES > 90 MM HG

INCOMPATIBLE WITH NaHCO3 SINCE ALKALINE ENVIRONMENT MAY INACTIVATE DOPAMINE

AVOID EXTRASATION WHICH WILL CAUSE TISSUE NECROSIS AND TISSUE SLOUGHING. INFORM ER RN OR MD SINCE LOCAL INJECTION OF RIGITINE WILL BE REQUIRED.

Question 7

STANDARD PREP

Answer 7

400 MG/250 CC ( PRE-MIXED)