NITROGLYCERINE (NITROSTAT)

Question 1

CLASS

Answer 1

NITRATE

ANTIANGINAL

Question 2

ACTIONS

Answer 2

RELAXES VASCULAR SMOOTH MUSCLE LEADING TO MARKED VENODILATION WHICH DECREASES PRELOAD WHICH IN TURN DECREASES INTRAMYOCARDIAL WALL TENSION, AND MILD TO MODERATE ARTERIAL DILATIONS WHICH DECREASES AFTERLOAD WHICH BOTH LEAD TO A DECREASE IN MYOCARDIAL OXYGEN DEMAND.

DILATES LARGE CORONARY ARTERIES, ANTAGONIZES VASOSPASM, AND INCREASES CORONARY COLLATERAL BLOOD FLOW TO ISCHEMIC MYOCARDIUM.

REDUCES SMOOTH MUSCLE SPASMS OF GI DISORDERS

Question 3

INDICATIONS

Answer 3

ANGINA PECTORIS

AMI

ACUTE HYPERTENSION

ACUTE PULMONARY EDEMA

Question 4

DOSAGE/ ROUTE

Answer 4

SEE HAWAII SO

ACLS- FOLLOW ALGORITHM

Question 5

STANDARD PREP

Answer 5

0.4 MG SL TABLETS, AEROSOL SPRAY DELIVERS 0.4 MG METERED DOSE

Question 6

CONTRAINDICATION

Answer 6

ALLERGY TO NITRATES

HYPOTENSION > 100 MM HG BEFORE NTG ADMINISTERED PER SO.

Question 7

SIDE EFFECTS

Answer 7

HEADACHE

DIZZINESS

FLUSHING

SYNCOPE

HYPOTENSION

RELEX TACHYCARDIA

STING UPON CONTACT WITH MUCOUS MEMBRANE

Question 8

PRECAUTIONS

Answer 8

MONITOR BP AND CHECK IF DRUG DISSOLVED SUBLINGUALLY

CAUTION TO EXPECT HA, DIZZINESS AND FLUSHING, A BURNING EFFECT UNDER TONGUE

IF POSSIBLE STORE IN DARK, COOL, DRY PLACE

ENVIRONMENTAL CONDTIONS MAY SHORTEN STATED EXPIRATIONS DATE

WHEN USING SPRAY, COACH PT. TO OPEN MOUTH WIDE AND LIFT TONGUE.

SIT UP PT. IF BP PERMITS IT AS YOU ADMINISTER NTG. SUPINE POSITION INCREASES PRELOAD AND OFFSETS BENEFITS

NITRATE-INDUCED HYPOTENSION RESPONDS WELL TO SUPINE POSITION THEN FLUID INFUSION PRN SINCE THERAPEUTIC EFFECTS ARE MORE A FUNCTION OF INTRAVASCULAR VOLUME STATUS THAN DOSE.