ATROPINE SULFATE

Question 1

CLASS

Answer 1

• PARASYMPATHOLYTIC

- ANTICHOLINERGIC (VAGOLYTIC)

Question 2

ACTIONS

Answer 2

• BLOCKS EFFECTS OF PARASYMPATHETIC INNERVATION TO THE HEART WHICH ENHANCES BOTH SINUS NODE AUTOMATICITY AND AV CONDUCTION
• RELAXES SMOOTH MUSCLE IN BRONCHIAL TREE = BRONCHODILATION
• INHIBITS GLANDULAR SECRETION IN RESPIRATORY TRACT
• INHIBITS SECRETION FROM SWEAT AND SALIVARY GLANDS
• DECREASES GI MOTILITY

Question 3

INDICATIONS

Answer 3

• SYMPATOMATIC BRADYARRHYTMIAS
• SYMPTOMATIC CONDUCTION DEFECTS, IE. STOKES-ADAM SYNDROME
• CPA (ASYSTOLE, PEA ALGORITHM)
• ORGANOPHOSPHATE (CHOLINERGIC) POISONING
• STATUS ASTHMATICUS (AEROSOL NEBULIZER ROUTE)

Question 4

DOSAGES / ROUTE

Answer 4

• SEE HAWAII SO.
• ACLS: FOLLOW ACLS ALGORITHM FOR BRADYCARDIA AND PEA
• POISONING: LARGE DOSE IV
• OTHER RESP. DIFF. : 1.0 mg via nebulizer with beta 2 agonist for adults.
• usual route IV, ET

Question 5

STANDARD PREPS

Answer 5

1 mg/ 10 cc preloaded syringe

Question 6

PEDS DOSE

Answer 6

SEE HAWAII SO AND PALS ALGORITHM

POISONING: AS DIRECTED BY BASE STATION

Question 7

SIDE EFFECTS

Answer 7

ACUTE PSYCHOSIS
VASODILATION
DEHYDRATION
ELEVATED SURFACE TEMP.
MYDRIASIS
mad as a hatter, red as a beet, dry as a bone, hot as a hare, blind as a bat.

Question 8

PRECAUTIONS

Answer 8

• MONITOR VS. EKG & MENTAL STATUS
• MAY INCREASE MYOCARDIAL 02 DEMAND IN MI PATIENTS AND AGGRAVATE CHEST PAIN.
• TOO LOW A DOSE MAY CAUSE PARADOXICAL BRADYCARDIA
• EXACERBATION OF GLAUCOMA
• CAN CAUSE ACUTE URINARY RETENTION IN MALES WITH ENLAGRED PROSTATE

Question 9

NOTE:

Answer 9

ACLS: ATROPINE HAS BEEN REPORTED TO BE HARMFUL IN SOME PATIENTS WITH AV BLOCK AT THE HIS- PURKINJE LEVEL (TYPE II AV BLOCK AND THIRD DEGREE AV BLOCK WITH A NEW WIDE-QRS COMPLEX).

-ATROPINE MAY BE USED IN THESE SITUATIONS BUT WATCH CLOSELY FOR PARADOXICAL SLOWING.