DIPHENHYDRAMINE ( BENADRYL )

Question 1

CLASS

Answer 1

ANTIHISTAMINE

H1 BLOCKER

Question 2

ACTIONS

Answer 2

BLOCKS HISTAMINE AT H1 RECEPTOR SITES ( COMPETES FOR THESE SITES ) WITH FOLLOWING EFFECTS IF SUCCESSFUL:

• REVERSAL OF HISTAMINE
• INDUCED VASODILATION
• REVERSAL OF HISTAMINE INDUCED INCREASED CAPIILARY PERMEABILITY

**NOTE: H1 RECEPTORS CAUSES BRONCHOCONS TRICTION AND CONTRACTION OF THE GUT

• REVERSES DRUG INDUCED EXTRAPYRAMIDAL REACTIONS (EPS) OF MUSCLE TREMOR AND RIGIDITY FROM PHENOTHIAZINES (TRILAFON, STELAZINE, COMPAZINE, PHENERGAN, THORAZINE, MELLARIL, PROLIXIN AND OTHERS) AND THE BUTYROPHENONES (HALDOL)

MILD SEDATIVE

Question 3

INDICATIONS

Answer 3

ALLERGIC REACTION

ANAPHYLAXIS, BENADRYL IS GIVEN AFTER EPINEPHRINE BECASE EPI CAUSES IMMEDIATE BRONCHODILATION OF ITS B2 EFFECTS AND VASOCONSTRICTION BY ITS ALPHA EFFECTS

ACUTE DYSTONIC REACTION (EPS)

Question 4

DOSAGE / ROUTE

Answer 4

SEE HAWAII SO

Question 5

STANDARD PREP

Answer 5

50 MG/ML

Question 6

PEDIATRIC DOSE

Answer 6

SEE HAWAII SO

Question 7

CONTRAINDICATIONS

Answer 7

HYPERSENSITIVITY

LOWER RESPIRATORY DISEASES SUCH AS ASTHMA ATTACKS

Question 8

SIDE EFFECTS

Answer 8

SEDATIONS

DRY MOUTH

THICKENING OF BRONCIAL SECRETIONS

HYPOTENSION (RARE)

Question 9

PRECAUTIONS

Answer 9

POTENTIATES EFFECTS OF ETOH / CNS DEPRESSION