AMINOPHYLLINE (THEOPHYLLINE) Flashcards
CLASS (3)
BRONCHODILATOR
METHYLXANTHINE
PHOSPHODIESTERASE INHIBITOR
ACTIONS (6)
BRONCHODILATION VIA INHIBITION OF PHOSPHODIESTERASE WHICH IN TURN PREVENTS BREAKDOWN OF cAMP. THIS INCREASED LEVELS OF cAMP IN TURN HAS THE SAFE EFFECT AS STIMULATING B-RECEPTORS
RESPIRATORY STIMULANT
MILD VASODILATION
CARDIAC STIMULANT WHICH INCREASES RATE AND FORCE OF CONTRACTION
MILD DIURESIS
CNS STIMULANT
ACTIONS (6)
BRONCHODILATION VIA INHIBITION OF PHOSPHODIESTERASE WHICH IN TURN PREVENTS BREAKDOWN OF cAMP. THIS INCREASED LEVELS OF cAMP IN TURN HAS THE SAFE EFFECT AS STIMULATING B-RECEPTORS
RESPIRATORY STIMULANT
MILD VASODILATION
CARDIAC STIMULANT WHICH INCREASES RATE AND FORCE OF CONTRACTION
MILD DIURESIS
CNS STIMULANT
INDICATIONS (3)
SECOND LINE DRUG FOR THE FOLLOWING:
ASTHMA
CHF/ACUTE PULMONARY EDEMA
EXACERBATION OF COPD
CONTRAINDICATIONS (3)
HYPERSENSITIVITY/ TACHYDYSRHYTHMIAS
HYPOTENSION / HYPOVOLEMIA
ANURIA
SIDE EFFECTS (11)
TREMORS
ANXIETY
HEADACHE
DIZZINESS
INSOMNIA
SEIZURES
HYPOTENSION
N & V
TACHYCARDIA
PVC’S
VENTRICULAR FIBRILLATION