ADENOSINE (ADENOCARD)

Question 1

CLASS

Answer 1

ANTIARRTHYMIC (ANTIDYSRHYTHMIC)

Question 2

ACTION

Answer 2

ENDOGENOUS NUCLEOSIDE (FOUND IN ALL CELLS OF THE BODY AND IS FORMED FROM THE BREAKDOWN OF ATP) DEPRESSES AV NODE AND SINUS NODE ACTIVITY

DECREASE CONDUCTION THROUGH THE AV NODE AND INTERRUPTS AV NODAL REENTRY PATHWAYS THAT CAUSE SVT.

WORKS BOTH AT THE AV NODE AND IN ABERRANT CONDUCTION PATHWAYS
- WPW (WOLF-PARKINSON-WHITE) OR LGL (LOWN-GANONG-LEVINE

DOES NOT CONVERT ATRIAL FIBRILLATION/FLUTTER BUT MAY TRANSIENTLY INCREASE AV BLOCK AND UNMASK FLUTTER WAVES. CLEARED FROM PLASMA IN < 30 SECONDS. HALF LIFE IS 10 SECONDS. A BRIEF PERIOD OF ASYSTOLE MAY LAST UP TO 15 SECONDS.

Question 3

INDICATIONS

Answer 3

SVT’S THOUGHT TO BE DUE TO REENTRANT MECHANISMS.

Question 4

STANDARD PREP

Answer 4

6 MG/2CC VIAL

Question 5

CONTRAINDICATIONS

Answer 5

HYPERSENSITIVTY

2ND OR 3RD DEGREE HEART BLOCK, OR SICK SINUS SYNDROME UNLESS HAS A FUNCTIONING PACEMAKER.

Question 6

SIDE EFFECTS

Answer 6

FLUSHING

CHEST PAIN

DYSPNEA

METALLIC TASTE

ARRHYTHMIAS: PAC’S, 2ND OR 3RD DEGREE HEART BLOCK, ASYSTOLE, VENTRICULAR ECTOPY,

BRONCHOCONSTRICTION

*NOTE: HAS A HALF LIFE OF 10 SECONDS, SO SIDE EFFECT ARE USUALLY TRANSIENT AND RESOLVE WITHIN 1-2 MINUTES.

Question 7

PRECAUTIONS

Answer 7

PATIENTS TAKING THEOPHYLLINES, CAFFEINE, OR THEOBROMINE MAY NEED HIGHER DOSES.

SMALL DOSE FOR PATIENTS WITH TRANSPLANTED HEARTS

REACTIVE AIRWAY DISEASE- INCREASE BRONCHOCONSTRICTION.