small intestine tumours Flashcards

1
Q

why is the small intestine protected against malignancy

A
  • high population of lymphoid tissue

- secretion of IgA

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2
Q

where is adenocarcinoma found

A

duodenum and jejunum

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3
Q

what is the most common tumour of the small intestine

A

adenocarcinoma

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4
Q

where are lymphomas found

A

ileum

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5
Q

what is the most common type of lymphoma

A

B cell type arising from MALT

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6
Q

what do most T cell lymphomas look like

A

ulcerated plaques or strictures in proximal small bowel

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7
Q

what are some factors that cause adenocarcinoma

A
  • coeliac

- crohns

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8
Q

what type of lymphoma does coeliac disease cause

A

T cell type

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9
Q

what does lymphoma present with

A
  • abdominal pain
  • diarrhoea
  • anorexia
  • weight loss
  • anaemia symptoms
  • palpable mass
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10
Q

what investigations can be done for lymphoma

A

ultrasound followed by MRI

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11
Q

what does ultrasound detect in lymphoma

A

mass lesion

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12
Q

treatment of adenocarcinoma

A

surgically remove the segmental resection

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13
Q

where do carcinoid tumours originate

A

enterochromaffin cells

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14
Q

where is the most common types of carcinoid tumours

A

appendix and terminal ileum

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15
Q

what is done for treatment of carcinoid tumour

A

surgery

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16
Q

what can carcinoids present with

A

liver enlargement due to metastases

17
Q

symptoms of carcinoid tumour

A
  • induced bluish-red flushing
  • abdominal pain
  • recurrent watery diarrhoea
18
Q

what do carcinoid tumours secrete

A
  • serotonin (5-HT)
  • bradykinin
  • histamine
  • prostaglandin
19
Q

what secreted by carcinoid tumours causes the diarrhoea and cardiac complications

A

5-HT

20
Q

what secreted by carcinoid tumours causes the blushing

A

bradykinin

21
Q

what is used to diagnose carcinoid tumour

A
  • ultrasound
  • urine
  • serum chromoganin A
22
Q

what is seen on ultrasound of carcinoid tumour

A

presence of liver secondary deposits

23
Q

what does urine show in carcinoid tumour

A

high concentration of 5-HT

24
Q

what is used to treat carcinoid tumour

A

ocreotide

alleviates flushing and diarrhoea

25
Q

what is Peutz-Jeghers syndrome

A

mucoocutaneous pigmentation and GI polyps

26
Q

what kind of inheritance is Peutz-Jeghers syndrome

A

autosomal dominant inheritance

27
Q

what is a characteristic is there of Peutz-Jeghers syndrome

A

brown buccal pigment

28
Q

where can Peutz-Jeghers syndrome occur

A

anywhere in GI tract mostly in small bowel

29
Q

what is treatment of Peutz-Jeghers syndrome

A

endoscopic polypectomy

30
Q

what may be necessary to reach the polyps in Peutz-Jeghers syndrome

A

balloon enteroscopy

31
Q

what is follow up for Peutz-Jeghers syndrome

A

yearly pan-endoscopy