Skin infections Flashcards
Bifonazole
Azole antifungal
Impair biosynthesis of ergosterol for cytoplasmic membrane, inhibiting fungal growth; fungistatic.
Clotrimazole
Azole antifungal
Impair biosynthesis of ergosterol for cytoplasmic membrane, inhibiting fungal growth; fungistatic.
Econazole
Azole antifungal
Impair biosynthesis of ergosterol for cytoplasmic membrane, inhibiting fungal growth; fungistatic.
Ketoconazole
Azole antifungal
Impair biosynthesis of ergosterol for cytoplasmic membrane, inhibiting fungal growth; fungistatic.
Miconazole
Azole antifungal
Impair biosynthesis of ergosterol for cytoplasmic membrane, inhibiting fungal growth; fungistatic.
Amorolfine
Antifungal
Interferes with synthesis of sterols essential for function of fungal cell membranes.
Ciclopirox
Antifungal
Chelates iron resulting in fungistatic or fungicidal activity against a broad spectrum of fungi. Also has anti-inflammatory activity.
Terbinafine
Antifungal
Chelates iron resulting in fungistatic or fungicidal activity against a broad spectrum of fungi. Also has anti-inflammatory activity.
Tolnaftate
Antifungal
Inhibits the growth of dermatophytes and Malassezia furfur. Exact mode of action unknown, but distorts hyphae and stunts mycelial growth. Inactive against Candida spp.
Clindamycin
Lincosamide antibacterial
inhibits growth of Cutibacterium (Propionibacterium) acnes.
Mupirocin
Antibacterial
Inhibits bacterial protein synthesis; effective against Gram-positive aerobes and some Gram-negative aerobes.
Silver sulfadiazine
Sulfonamide
Bactericidal; binds to cell membranes; effective against many Gram-positive and Gram-negative bacteria.
Sodium fusidate/ Fusidic acid
Antibacterial
Staphylococcal skin infections (on specialist advice if other options unsuitable)
Aciclovir
Antiviral
Idoxuridine
Antiviral
