Síndrome Poliglandular Autoimune Flashcards

1
Q

Definicao:

A

a

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2
Q

Classificacao:

A

SPA-1, 2, 3 e 4

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3
Q

Epidemiologia:

A

a

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4
Q

Etiologia:

A

SPA-1: Mutações do gene regulador autoimune AIRE

SPA-2: HLA-B8 e DR-3

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5
Q

Critérios Classificatórios da *SPA-1:

*Poliendocrinopatia autoimune-candidíase-distrofia ectodérmica

A

(2+):

Candidiase cronica, hipoparatireoidismo e Doenca de Addison

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6
Q

Criterios Classificatorios da *SPA-2:

*Sindrome de Schmidt

A

Doença de Addison + (Doença tireoidiana autoimune e/ou DM tipo 1)

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7
Q

Criterios Classificatorios da SPA-3:

A

Doenca tireoidiana autoimune + *outra doenca autoimune

*Exceto Doenca de Addison, Hipoparatireoidismo e candidiase cronica

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8
Q

Criterios Classificatorios da SPA-4:

A

2+ *doencas autoimunes orgao-especificas

*Exceto hipoparatireoidismo, candidiase mucocutanea cronica, doenca tireoidiana autoimune e DM tipo 1

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