Sexual differentiation SDL Flashcards
1
Q
What are the 3 levels of sexual dimorphism
A
Genetic
Gonadal
Phenotypic
2
Q
What about cell cause them to express female genes and inhibit male genes?
A
No SRY gene
3
Q
What process protects the female brain from the masculinising effects of oestradiol
A
Alpha-fetoprotein binds to oestradiol from the ovaries
This complex cannot cross the BBB so the surge centre can develop
4
Q
How does oestradiol masculinise the male brain?
A
Testosterone secreted into blood from testes crosses BBB and is converted to oestradiol and dihydrotestosterone which inhibits the development of the surge centre
5
Q
What is the role of thecal cells?
A
produce oestrogen
6
Q
A
