Fluid therapy Flashcards

1
Q

What ways do we lose fluid?

A

Urine
Faeces/diarrhoea
Vomit
Blood loss
Third space loss
Inflammatory exudate
Insensible losses
Redistriubtion

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2
Q

Explain fluid loss via vomiting

A

Loss of acid (HCl) => metabolic alkalosis

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3
Q

Explain fluid loss via blood loss

A

Can be external or internal e.g., bleeding splenic haemangiosarcoma (tumour)
Loss of blood => loss of O2 supply => anareobic respiration => lactic acid formation => acidosis

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4
Q

Describe fluid loss via third space loss

A

Third space = body cavities e.g., abdomen
Fluid can be a transudate (low protein and cells), modified transudate (high protein, low cells) or exudate (high protein and cells) depending on disease
Loss of fluid +/- proteins => reduced blood volume => poor oxygen supply => anaerobic respiration => lactic acid formation => acidosis

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5
Q

Explain fluid loss via inflammatory exudate

A

Loss of fluid due to inflammation e.g., burns
Burns lead to fluid and protein loss from site

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6
Q

Explain fluid loss via insensible losses

A

e.g., sweating, breathing
can be significant e.g., sweating in exercising horses

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7
Q

Explain fluid loss via redistribution

A

a relative loss
Relates to hypovolaemia and distributive shock
In ‘distributive’ disease blood vessels dilate => more fluid needed to fill vessels back up
Peripheral vasodilation causes a relative hypovolaemia due to change in capacticance

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8
Q

Define dehydration

A

Loss of fluid from intracellular and interstitial compartments

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9
Q

Define hypovolaemia

A

loss of fluid from intravascular space

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10
Q

How can you check for hypovolaemia?

A

poor Pulse quality
pale Mucous membrane
long CRT
high Heart rate
low rectal temp
Blood parameters

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11
Q

What are the clinical signs of dehydration?

A

Prolonged skin tent
Tacky or dry mucous membranes
Sunken and dull eyes
Weight loss

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12
Q

what is shock?

A

Tissue hypoxia (low oxygen) due to:
- reduced O2 delivery
- excessive O2 demand/usage
- inadequate utilisation of O2

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13
Q

What are the 4 types of shock causing reduced delivery?

A

Hypovolaemic:
- e.g. haemorrhagic
- BP drops => reduced perfusion of tissues
Distributive:
- vasodilation => reduced ability of blood to fill vessels => reduced BP => reduced perfusion of tissues
Cardiogenic:
- ‘pump’ no longer working effectively => reduced BP => reduced perfusion of tissue
Obstructive:
- BV blocked or compressed so blood cannot reach tissues

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14
Q

How can you diagnose hypovolaemic shock?

A

same as hypovolaemia:
poor Pulse quality
pale Mucous membrane
long CRT
high Heart rate
low rectal temp
Blood parameters

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15
Q

How can distributive shock be diagnosed?

A

Dark pink/red mucous membranes
Quick capillary time
Normal or high temp
Reduced BP:
- weak pulse

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16
Q

Why does dehydration cause sunken eyes

A

Loss of fluid and cells from fat pad behind eyes

17
Q

What are the 3 types of fluids?

A

Crystalloids - isotonic, hypertonic, hypotonic
Colloids
Transfusion products

18
Q

Explain isotonic fluid uses

A

Used for fluid resuscitation for hypovolaemia and dehydration
Equilibrate across membranes to restore both intra and extra vascular spaces => intravascular volume expansion can be short lived

19
Q

Give examples of isotonic fluids

A

Hartmann’s:
- Contains Na, Cl, Ca, lactate, Mg
- Especially useful in metabolic acidosis
Sodium chloride:
- less balanced in terms of electrolytes
- quite acidifying
Dextrose solutions:
- glucose in it is rapidly metabolised leaving NaCl
- really a hypotonic fluid

20
Q

Explain the use of hypertonic fluids

A

Saline solutions (7.2%):
- IV
- draws fluid into intravascular space from interstitial space (do not use in dehydration)
- useful for hypovolaemic shock
- draws fluid from brain so useful in head trauma
- always follow with isotonic solutions

21
Q

Explain hypotonic fluid use

A

Saline solutions (0.45%):
- rarely used
- used in hypernatraemia (high Na in blood) to dilute it down
- if drop blood Na too fast => creates osmotic gradient into brain => floods brain => cerebral oedema

22
Q

Describe the use of colloid fluids

A

contain macromolecules which mimic albumin (protein) in the blood to provide oncotic pressure
Provide a constant buff to intravascular volume by helping to retain fluids
Have been shown to increase risk of death and acute kidney injury

23
Q

Describe the use of transfusion products

A

Used to replace what’s been lost
Whole blood for haemorrhage
Packed RBCs for anaemia
Fresh frozen plasma for loss of clotting factors
Risk of transfusion reaction so administer slowly

24
Q

What are the routes of fluid administration?

A

Intravenous:
- rapid and continuous
- useful for hypovolaemia and dehydration
Intraosseous:
- isotonic fluids only
Subcutaneous:
- relies of subcut blood supply to redistribute fluid
- only appropriate in mild dehydration
Oral:
- relies of functioning GIT
Rectal:
- for dehydration rather than hypovolaemia
Intraperitoneal:
- dependent on good peritoneal blood supply

25
Q

How do you calculate the rate to administer fluids in dehydration?

A

deficit + maintenance + ongoing losses

26
Q

What is front loading and conservative fluid rates?

A

Front loading - replace 1/2 deficit in 1-4 hrs, remainder over 24 hrs
Conservative - replace over 24 hrs

27
Q

what rates should be used for transfusions?

A

Slow initially - 0.25-0.5 ml/kg/hr for 30 mins
If no signs of reaction => 3-6ml/kg/hr for 3-4hrs

28
Q

What methods are there for setting rate of fluid therapy?

A

Burette:
- relies of gravity
Mechanical:
- drip pump
- syringe driver
- pressure bags

29
Q

how do we monitor fluid therapy?

A

Weight gain
blood pressure increase
Lactate reduces
Clinical signs cease
Urine output increases

30
Q

what are the signs of fluid overload

A

Weight increase in excess of target weight
Hypertension
Peripheral oedema
Effusions
Pulmonary oedema