Histology of non-pregnant female Flashcards
Label the female repro system
What is the function of the ovaries?
production of female gametes/oocytes/eggs
Production of female sex steroids
Describe the anatomy of the ovaries
Cortex: outer parenchymatous zone containing follicle and corpus luteums
Medulla: inner vascular zone
Stroma: spindle-shaped cells that surround ovarian follicles
Label the ovarian histology
Describe the formation of an ovarian follicle
Follicle composed of an oocyte surrounded by specialised epithelial cells (granulosa/cumulus)
During follicular development, epithelial cells become surrounded by theca cells (Specialised stroma) and a fluid-filled cavity develops among epithelial cells
These layers are separated by a basement membrane
Describe the structure of a primordial follicle
Least developed and most numerous
Primary oocyte surrounded by simple squamous epithelial granulosa cells
Describe the structure of a primary follicle
The first developmental stage
primary oocyte surrounded by simple cuboidal epithelila granulosa cells
Describe the structure of a secondary follicle
Granulosa cells proliferate and form a stratified epithelium (multiple layers of granulosa cells)
Describe the structure of an early antral follicle
Characterised by a fluid-containing cavity (the antrum)
Theca cells differentiate into 2 layers (interna and externa)
Describe the structure of the antral/tertiary/Graafian follicle
The granulosa cells form a thickened mound (cumulus oophorus) which projects into the antrum
What stage of follicle development is this?
Primordial
What stage of follicle development is this?
Primary follicle
What stage of follicle development is this?
Secondary follicle
What stage of follicle development is this?
Early antral follicle
What stage of follicle development is this?
Antral/tertiary/Graafian follicle