Sex Steroid Drugs

Question 1

Example of a COCP

Answer 1

Microgynon

Question 2

Mechanism of action of COCPs

Answer 2

Feedback on hypothalamus to prevent ovulation, Some thickening of cervical mucus and thinning of endometrium

Question 3

ADRs of COCPs

Answer 3

Mood changes, Headaches, Gall stones, Nausea, Vomiting, Weight gain, Hypertension, Thrombosis, Breast cancer

Question 4

DDIs of COCPs

Answer 4

Effected by inducers and inhibitors

Question 5

Monitoring with COCPs

Answer 5

BP

Question 6

Example of POPs

Answer 6

Cerazette

Question 7

Mechanism of action of POPs

Answer 7

Thicken cervical mucus, Thin endometrium

Question 8

ADRs of POPs

Answer 8

Mood changes, Breast tenderness, Abdo cramps, Irregular periods, Heavy bleeding

Question 9

DDIs of POPs

Answer 9

Effected by inducers and inhibitors

Question 10

Natural methods of contraception

Answer 10

Rhythm, Coitus interuptus

Question 11

Barrier methods of contraception

Answer 11

Condom, Femidom, Diaphragm

Question 12

Medical methods of contraception

Answer 12

COCPs, POPs, Implants, IUDs, Emergency contraceptive pill

Question 13

Surgical methods of contraception

Answer 13

Vasectomy, Ligation of fallopian tubes

Question 14

Mechanism of action of HRT

Answer 14

Replace lost hormones

Question 15

ADRs of HRT

Answer 15

Endometrial cancer, Ovarian cancer, Breast cancer, Heart disease, Stroke, Thrombosis, Uterine bleeding

Question 16

Method to reduce risk of endometrial cancer with HRT

Answer 16

Oestrogen only or hysterectomy

Question 17

DDIs of HRT

Answer 17

Effected by inducers and inhibitors