Antiviral Drugs Flashcards
1
Q
Examples of M2 channel blockers
A
Amantidine, Rimantidine
2
Q
Mechanism of action of M2 channel blockers
A
Block M2 ion channel, preventing H influx, preventing uncoating
3
Q
ADRs of M2 channel blockers
A
GI upset, Dizziness, Hypotension, Confusion, Insomnia, Hallucinations
4
Q
Examples of neurominidase inhibitors
A
Zanamivir, Oseltamivir
5
Q
Mechanism of action of neurominidase inhibitors
A
Competitively bind to neurominidase, prevents new virons from budding off
6
Q
ADRs of neurominidase inhibitors
A
GI upset, Headaches, Nose bleeds, Resp depression, Bronchospasm
7
Q
When should treatment with neurominidase inhibitors should be started
A
Within 48hrs of symptoms
