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Pharmacology > Anti-arrhythmic Drugs > Flashcards

Anti-arrhythmic Drugs Flashcards

1
Q

Examples of Class I anti-arrhythmic Drugs

A

Lidocaine, Flecainide

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2
Q

Mechanism of action of Class I anti-arrhythmic Drugs

A

Block Na channels, Slow conductance in phase 0 of cardiac action potential

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3
Q

ADRs of Class I anti-arrhythmic Drugs

A

Hypotension, Long QT, Dizziness, Confusion, Insomnia, Seizures, GI upset

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4
Q

Indications for Class I anti-arrhythmic Drug use

A

Rhythm control -AF

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5
Q

Examples of Class II anti-arrhythmic Drugs

A

Atenolol, Bisoprolol

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6
Q

Mechanism of action of Class II anti-arrhythmic Drugs

A

Beta blockers, Reduce SNS input slowing conduction through the AV node

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7
Q

ADRs of Class II anti-arrhythmic Drugs

A

Bronchospasm, Hypotension, Reduced contractility

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8
Q

Indication for Class II anti-arrhythmic Drug use

A

Rate control -SVT, Sinus tachycardia

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9
Q

Examples of Class III anti-arrhythmic Drugs

A

Amiodarone, Sotalol

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10
Q

Mechanism of action of Class III anti-arrhythmic Drugs

A

Block K channels preventing repolarisation increasing the refractory period

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11
Q

ADRs of Amiodarone

A

Arrhythmia, Pulmonary fibrosis, Photosensitivity, Thyroid disease, Liver damage

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12
Q

ADRs of Sotalol

A

Arrhythmia, Fatigue, Insomnia

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13
Q

Indications for Class III anti-arrhythmic Drug use

A

Rhythm control - most arrhythmias

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14
Q

Example of Class IV anti-arrhythmic Drugs

A

Verapamil

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15
Q

Mechanism of action of Class IV anti-arrhythmic Drugs

A

Block Ca channels, reducing influx of Ca in the cardiac and pacemaker potentials, slowing conductance through the AV node

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16
Q

ADRs of Verapamil

A

Hypotension, GI upset

17
Q

Indications for Class IV anti-arrhythmic Drug use

A

Rate control - SVT

18
Q

Mechanism of action of Adenosine

A

Activate alpha 1 receptors opening K channels, causes hyperpolarisation increasing the refractory period, slows conductance through the AV node

19
Q

ADRs of Adenosine

A

Nausea, Lightheadedness, Sense of impending doom

20
Q

Indications for Adenosine use

A

Acute management of SVT

Pharmacology (24 decks)

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