Opioid Drugs Flashcards
1
Q
Examples of opioid drugs
A
Morphine, Codeine
2
Q
Mechanism of action of opioid drugs
A
Act on opioid receptors to reduce intracellular Ca in neurones reducing neurotransmitter release
3
Q
Effect of mew opioid receptors
A
Promote K efflux
4
Q
Effect of delta opioid receptors
A
Reduce cAMP
5
Q
Effect of kappa opioid receptors
A
Decrease Ca influx
6
Q
ADRs of opioid drugs
A
Resp depression, Nausea, Vomiting, Drowsiness, Constipation, Psychosis, Hypotension, Dependence, Constriction of pupils
7
Q
Treatment of opioid overdose
A
Naloxone