Sept. 11, 2019 Flashcards

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1
Q

In 1 sentance, describe INFLAMMATION

A

A localized VASCULAR response to INJURY

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2
Q

Is INFLAMMATION more geared towards defense or healing?

A

Both!

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3
Q

What makes up VASCULAR TISSUE?

A

BLOOD and BLOOD VESSELS

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4
Q

“itis” at the end of a word indicates what?

A

INFLAMMATION

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5
Q

Can a CELL become INFLAMED?

A

No

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6
Q

3 main aims of INFLAMMATION?

A

1) Localize injurious agents
2) Restrict and remove PATHOGENS
3) Assist w healing

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7
Q

Foreign agents, CELLS, and debris must be removed before ________ can take place.

A

Healing

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8
Q

Explain ACUTE INFLAMMATION

A

Has a quick/immediate onset, short duration, and precedes the immune response

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9
Q

Which GRANULOCYTE is predominantly involved in ACUTE INFLAMMATION?

A

NEUTROPHILS

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10
Q

Explain CHRONIC INFLAMMATION

A

Long term (could last for weeks or years), is self-maintaining

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11
Q

Which CELLS are predominantly involved in CHRONIC INFLAMMATION?

A

LYMPHOCYTES and MACROPHAGES

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12
Q

What is ANGIOGENESIS?

A

The formation of new BLOOD VESSELS (BV)

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13
Q

What is FIBROSIS?

A

The formation excess FIBROUS CONNECTIVE TISSUE (CT)

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14
Q

What is NECROSIS?

A

CELL death in an ORGAN or TISSUE caused by external factors

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15
Q

Which 2 responses are involved in ACUTE INFLAMMATION?

A

1) VASCULAR

2) CELLULAR

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16
Q

Does HEMOSTASIS happen quickly or slowly after an injury?

A

Quickly

17
Q

What is HEMOSTASIS?

A

The stoppage of bleeding

18
Q

When would VASOCONSTRICTION (VASOCON) occur following an injury?

A

Stat after injury to minimize B loss

19
Q

Which INFLAMMATORY MEDIATORS (INFLM MED) are released during an ACUTE response?

A

HISTAMINES and PROSTAGLANDINS

20
Q

Give 2 effects of INFLM MEDs

A

1) VASODILATION

2) Pain

21
Q

Explain the role of VASODILATION (VASODIL) in an INFLM response

A

VASODIL causes HYPEREMIA, ERYTHEMA, warmth, inc. PERMEABILITY

22
Q

What is HYPEREMIA?

A

An excess or increase of B

23
Q

What is ERYTHEMA?

A

Redness

24
Q

What effect does inc PERMEABILITY have on BVs?

A

More particles, referred to as EXUDATE, are able to leave the BV because of the inc PERMEABILITY

25
Q

What is in EXUDATE?

A

Fluid, CELLs, PROTEINS

26
Q

Swelling is a side effect of…

A

…inc PERMEABILITY

27
Q

What is a benefit of pain?

A

Pain will result in immobilization to reduce movement and therefore reduce the pain

28
Q

The ROULEAU formation of RBCs will cause what?

A

B flow to slow down

29
Q

Explain DIAPEDESIS

A

The process of EXUDATE leaving a BV d/t inc PERMEABLITY

30
Q

Explain TRANSMARGINATION

A

The process of EXUDATE leaving a BV d/t inc PERMEABLITY

31
Q

Explain EMIGRATION

A

The process of EXUDATE leaving a BV d/t inc PERMEABLITY

32
Q

What is the result of INFLM MEDs in the CELLULAR response?

A

Attracting NEUTROPHILS and othe WBCs to the site of INJURY using the process of CHEMOTAXIS

33
Q

The adhesion molecule SELECTIN aids in what process?

A

MARGINATION