Oct. 30, 2019 Flashcards
Where are NATRIURETIC PEPTIDES produced?
The HEART
What is NATRIURESIS?
Increased excretion of Na in urine
What happens to Na when H20 moves somewhere?
Na follows
Are NATRIURETICS dilatory or constricting?
VASODILATORY
The overall goal of NATRIURETIC PEPTIDES is to..?
Reducing the workload of the HEART
What effect do ENDOTHELINS have on BVs?
They cause VASOCON
What effect do ENDOTHELINS have on CARDIAC MUSCLE?
They cause CARDIAC HYPERTROPHY
What effect do ENDOTHELINS have on VASCULAR MUSCLE?
They cause proliferation
Increased workload on HEART results in..?
HYPERTROPHY
When the HEART is working harder, it requires more of what?
More o2 and ATP
What kind of failure occurs when the compensatory mechanisms fail?
UNCOMPENSATED FAILURE
Mnfts of UNCOM HF
There are several, those related to impaired pumping, those from the SNS
Diagnostics for UNCOM HF
This is complex
- Past history
- ECG
- Echo
- Labs
Which labs would you want specifically?
- Anemia
- Electrolytes
- Liver Fx
Abdom organ Fx
Before proceeding w treatment what has to happen?
pt needs to be stablized and cause of HF needs to be determined
What meds would you use for SYSTOLIC HF?
- ACEI
- Beta blocker
What does the EF generally look like for SYSTOLIC HF?
< 40%
What is the treatment if EF is equal to or greater than 40%
- First treat cause
- ACEI
- Beta blocker
- Angiotensin 2 receptor blocker if symptoms w activity
- inc med dose or add diuretic if symptoms at rest
Is HF ACUTE or CHRONIC?
Can be either
Is surgery ever an option for treating HF?
Sometimes
