Salbutomol

Question 1

What is the Pharmacology of Salbutomol

Answer 1

A synthetic Beta adrenergic stimulant with primary Beta 2 effects.
- Causes Bronchodilation

Question 2

What is the Presentation of Salbutomol and how is it Metabolized.

Answer 2

Presentation

• 5mg in 2.5ml
• pMDI (100mcg per/ actuation).

Metabolism
- by the liver and excreted by the kidneys.

Question 3

What are the Indications and Contraindication of Salbutomol

Answer 3

Indications (SOS-CA)

• Asthma
• COPD
• Oleo-resin (capsicum spray) exposure.
• Smoke inhalation
• Severe Allergic Reaction.

Contraindication
- Nil of Significance.

Question 4

What are the Side Effects and Precautions of Salbutomol

Answer 4

Side Effects

• Tachycardia
• Muscle Tremors

Precautions
- Large amounts of Salbutomol can cause intracellular metabolic acidosis.

Question 5

Route of Administration and Special Notes

Answer 5

Route of Administration

• Nebulised
• Actuation

Special Notes

• Although rare, Salbutomol infusions may be required for inter-hospital transfer for some women in premature labour. ( The dose is singed and prescribed by the referring hospital medical officer).
• Onset: 5 - 15 Minutes
• Peak: N/A
• Duration: 15 - 50 Minutes