Ceftriaxone Flashcards
1
Q
What is Ceftriaxone Pharmacology
A
Cephalosporin Antibiotic.
- Ceftriaxone selectively and irreversibly inhibits bacterial cell wall synthesis by binding to transpeptidases
2
Q
What is the Presentation of Ceftriaxone and how is it metabolized.
A
Excreted in Urine.
3
Q
What are the Indications and Contraindications
A
Indications
- Suspected Meningococcal Septicemia.
- Severe Sepsis (Consult only)
Contraindication
- Allergy to Cephalosporin Antibiotic
4
Q
What are the Precautions and Side Effects of Ceftriaxone
A
Side Effects.
- Nausea/ Vomiting
- Skin Rash
Precautions
- Allergy to Penicillin.
5
Q
Special Notes
A
Usual Dose:
- 1g for Adults
- 50mg/kg (Max 1g) for children.
Ceftriaxone IV
- Must be made up and diluted to 10ml using sterile water and Administered over 2 Minutes.
Ceftriaxone IM
- Must be made up to 4ml using 1% lignocaine and given in the lateral thigh.
