Lignocaine

Question 1

What is the Pharmacology of Lignocaine

Answer 1

Local Anesthetic

• Sodium Channel Blocker.
• Interrupts impulse conduction in peripheral nerves and stabilizes excitable cell membranes.

Question 2

What is the Presentation of Lignocaine and how is it Metabolize.

Answer 2

Presentation
50mg in 5ml.

Metabolism

Question 3

What are the Indications and Contraindications of Lignocaine.

Answer 3

Indication 
Local Anesthetic to reduce pain with 
- Ceftrixone Administration 
- Chest Decompression in pts with GCS less than 10 (MICA) 
- IO Administration in conscious pts. 

Contraindications.
- Hypersensitivity to lidocaine or any relevant anesthetics (Bupivaccine, Levobupvacaine, Prilocane, Ropivacaine.)

Question 4

What are the Side Effects and Precautions of Lignocaine

Answer 4

Side Effects

• Allergic reaction are rare and may present with localized oedema, urticaria, bronchospasm, Anaphylaxis.
• Signs of Systemic toxicity
  
  • CNS: Tinnitus, Blurred Vision, Sudden change in conscious state, agitation and/ or convulsions.
  • CV: Hypotension, Bradycardia, Arrhythmia’s (Conduction blocks, Ventricular Tachyarrythmias)

Precautions

• IM: Inadvertent intravascular administration may result in systemic toxicity.
• IO: Impaired CV function (Hypotension, Bradycardia, poor perfusion, heart block and heart failure).

Question 5

Route of Administration and Special Notes

Answer 5

Route of Administration
IM, IO.

Special Notes

• Lidocaine and Lignocaine are the same medication.
• Onset: 1 - 5 minutes
• Duration: 1 - 1.5 Hours.